Enzyme Inhibition

What are the 2 types of enzyme inhibitors?

How do competitive inhibitors work?

What happens to competitive inhibition when the concentration of substrates increases?

How do non-competitive inhibitors work?

What happens to non-competitive inhibition when the concentration of substrates increases?

Enzymes inhibitors can either be reversible or non-reversible. What does this depend on?

How do covalent bonds between the enzyme and inhibitor affect inhibition?

How do hydrogen/ionic bonds between the enzyme and inhibitor affect inhibition?

What is a metabolic pathway?

How are metabolic pathways regulated?

What is end-product inhibition?

Complete the sentences:
End-product inhibition is ____________, so when the level of the end-product drops, _________drops and so more product can be made. This is a good way of ___________ the pathway and controlling the amount of ______-___________ that gets made. This is a ___________ ___________ mechanism.

What do metabolic poisons do?

Give examples of metabolic poisons

TRUE OR FALSE:
Some medicinal drugs are enzyme inhibitors

Name examples of medicinal drugs which act as enzyme inhibitors

How does aspirin act as an enzyme inhibitor?

How do ATPase inhibitors act as enzyme inhibitors?

How do ACE inhibitors act as enzyme inhibitors?

How do protease inhibitors act as enzyme inhibitors?

How do nucleoside reverse transcriptase inhibitors act as enzyme inhibitors?