Neuromuscular Blockade

Pregunta 1 de 16

1

Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:

Selecciona una de las siguientes respuestas posibles:

80 y.o. female patient 2 days after 40% body surface area burn
18 y. o. male one week after spinal cord transection injury
12 y.o. with Duchene’s muscular dystrophy
22 y. o. with evolving respiratory failure secondary to Guillian-Barre’
27 y. o. female with myasthenia gravis

Explicación

Pregunta 2 de 16

1

A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:

Selecciona una de las siguientes respuestas posibles:

Quinidine
Phenytoin
Cyclophosphamide
Aminoglycosides
Magnesium

Explicación

Pregunta 3 de 16

1

The MOST important parameter that determines the speed of onset for NMB drugs is:

Selecciona una de las siguientes respuestas posibles:

Potency
Lipophilicity
Ionization
Plasma clearance
E. Receptor affinity

Explicación

Pregunta 4 de 16

1

A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:

Selecciona una de las siguientes respuestas posibles:

Significant histamine release after a bolus injection
Vagolysis producing tachycardia
Hofmann elimination
Deacetylation in the liver
Production of laudanosine as the primary metabolite

Explicación

Pregunta 5 de 16

1

Selecciona la opción correcta del menú desplegable para completar el texto.

Clinical data support that when the TOFR exceeds ( 0.4, 0.2, 0.7, 0.9 ),
anesthesia providers have trouble assessing the presence
of fade

Explicación

Pregunta 6 de 16

1

Selecciona la opción correcta del menú desplegable para completar el texto.

TOF count of 3 would equate to a twitch suppression of ( 55, 75, 85, 90 )%

Explicación

Pregunta 7 de 16

1

Selecciona la opción correcta del menú desplegable para completar el texto.

Once the TOF ratio exceeds ( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively

Explicación

Pregunta 8 de 16

1

What is true about Tetanic stimulation (TET)?

Selecciona una de las siguientes respuestas posibles:

During partial depolarizing block, fade is not observed in response to tetanic stimulation
Tetanic stimulation is not painful
Muscular fatigue usually develop at a stimulation frequency of 50 Hz
Fade is thought to be an effect of a depolarizing agent on the presynaptic nerve membrane

Explicación

Pregunta 9 de 16

1

Which statement about posttetanic count is NOT correct?

Selecciona una de las siguientes respuestas posibles:

The number of posttetanic count twitches is inversely related to time until the first regular TOF twitch returns
Posttetanic count used when TOF or DBS is absent to estimate recovery time
Posttetanic count uses tetany followed by TOF at frequency of 1 Hz
The main use of posttetanic count is when profound neuromuscular block is not required

Explicación

Pregunta 10 de 16

1

Correct statements about objective monitoring techniques include:

Selecciona una de las siguientes respuestas posibles:

Mechanomyography (MMG) measures isotonic contraction of peripheral muscles in response to nerve stimulation
Acceleromyography (AMG) calculates the force of contraction of a muscle using a miniature piezoelectric transducer
Electromyography (EMG) measures the electrical activity (compound muscle action potential) of a stimulated muscle
Kinemyography (KMG) detects the acceleration of the thumb contraction in response to electrical stimulation of a nerve

Explicación

Pregunta 11 de 16

1

All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:

Selecciona una de las siguientes respuestas posibles:

D-tubocurarine
Atracurium
Mivacurium
Pancuronium
Cisatracurium

Explicación

Pregunta 12 de 16

1

Train-of-four (TOF) has all of the following characteristics, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

TOF consists of four ST stimuli at a frequency of 4 Hz
TOF does not require a “baseline” or “control” muscle response
TOF “fade” is defined as a weaker fourth twitch than the first twitch
TOF is delivered every 15-20 sec to prevent potentiation of subsequent responses
TOF ratios >0.40 cannot be reliably detected subjectively (visually or tactilely)

Explicación

Pregunta 13 de 16

1

Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

The two mini-tetanic bursts are separated by 0.5 sec
DBS is delivered no more frequently than every 20 sec to prevent subsequent response potentiation
In DBS, similar to TOF pattern, no control (“baseline”) muscle response is needed
DBS ratios >0.60 cannot be reliably detected by subjective (tactile, visual) means
In awakening patients, DBS is more painful than TOF, but less so than tetanic stimulation

Explicación

Pregunta 14 de 16

1

Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

Myalgia
Tachycardia
Anaphylaxis
Hyperkalemia

Explicación

Pregunta 15 de 16

1

Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 16 de 16

1

When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:

Selecciona una de las siguientes respuestas posibles:

Verapamil
Dexamethasone
Ranitidine
Odansetron

	Creado por Mike Ru hace alrededor de 6 años

Diplomat of ABA (Fundamental Topics in Anesthesiology) Medicine Test sobre Neuromuscular Blockade, creado por Mike Ru el 28/04/2018.

Neuromuscular Blockade

Neuromuscular Blockade

Pregunta 1 de 16

Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 2 de 16

A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 3 de 16

The MOST important parameter that determines the speed of onset for NMB drugs is:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 4 de 16

A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 5 de 16

Selecciona la opción correcta del menú desplegable para completar el texto.

Clinical data support that when the TOFR exceeds 0.4 0.2 0.7 0.9( 0.4, 0.2, 0.7, 0.9 ), anesthesia providers have trouble assessing the presence of fade

Explicación

Pregunta 6 de 16

Selecciona la opción correcta del menú desplegable para completar el texto.

TOF count of 3 would equate to a twitch suppression of 55 75 85 90( 55, 75, 85, 90 )%

Explicación

Pregunta 7 de 16

Selecciona la opción correcta del menú desplegable para completar el texto.

Once the TOF ratio exceeds 0.60 0.40 0.70 0.85( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively

Explicación

Pregunta 8 de 16

What is true about Tetanic stimulation (TET)?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 9 de 16

Which statement about posttetanic count is NOT correct?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 10 de 16

Correct statements about objective monitoring techniques include:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 11 de 16

All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 12 de 16

Train-of-four (TOF) has all of the following characteristics, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 13 de 16

Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 14 de 16

Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 15 de 16

Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.

Selecciona uno de los siguientes:

Explicación

Pregunta 16 de 16

When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:

Selecciona una de las siguientes respuestas posibles:

Explicación

Clinical data support that when the TOFR exceeds ( 0.4, 0.2, 0.7, 0.9 ),
anesthesia providers have trouble assessing the presence
of fade

TOF count of 3 would equate to a twitch suppression of ( 55, 75, 85, 90 )%

Once the TOF ratio exceeds ( 0.60, 0.40, 0.70, 0.85 ), fade to DBS generally cannot be detected subjectively