GEGE2001 Week 03 (L05 & L06)

Pregunta 1 de 15

2

(from end of L05 slides)
In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

Selecciona una de las siguientes respuestas posibles:

Polymerase *probs* removes it, often via 3' exonuclease activity
Polymerase *probs* removes it, often via 5' exonuclease activity
Polymerase *probs* removes it, often via 3' endonuclease activity
Polymerase *probs* removes it, often via 5' endonuclease activity

Explicación

Pregunta 2 de 15

2

(from end of L05 slides)
How does a frameshift mutation differ from a missense mutation?

Selecciona una de las siguientes respuestas posibles:

Missense affects many codons; Frameshift mutation does not.
Frameshift affects many codons; Missense mutation does not.
Frameshift affects many codons; Missense mutation only affects 3.
Missense affects many codons; Frameshift mutation only affects 3.

Explicación

Pregunta 3 de 15

2

(from end of L05 slides)
Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain here, but be ready to)

Selecciona una de las siguientes respuestas posibles:

No.
Yes.

Explicación

Pregunta 4 de 15

1

DNA is replicated in:

Selecciona una de las siguientes respuestas posibles:

S phase
M phase
G phase
Cytokinesis
Telekinesis

Explicación

Pregunta 5 de 15

2

UV:

Selecciona una o más de las siguientes respuestas posibles:

light has HIGH energy
light has LOW energy
damage forms a join between two adjacent bases, usually Thymine (forming a Thymine dimer)
damage forms a join between two adjacent bases, usually Cytosine (forming a Cytosine dimer)
damage forms a join between two adjacent bases, usually Adenosine (forming a Adenosine dimer)
damage forms a join between two adjacent bases, usually Guanine (forming a Guanine dimer)
damage forms a join between two adjacent bases, usually Adenine (forming a Adenine dimer)

Explicación

Pregunta 6 de 15

1

Which of the following is NOT a type of DNA mutation (necessarily)?

Selecciona una o más de las siguientes respuestas posibles:

Indels
Incels
Transitions
Transversions

Explicación

Pregunta 7 de 15

2

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks:
Silent mutation: ❌;
Missense mutation: ❌;
Nonsense mutation: ❌;
Frameshift ❌.

Arrastra y suelta para completar el texto.

bp change, NO amino acid sequence change

bp change, amino acid change

bp change, early stop codon

1bp+ indel, alters reading frame

Explicación

Pregunta 8 de 15

1

UV repair in humans is through:

Selecciona una o más de las siguientes respuestas posibles:

Nucleotide excision repair
Enzyme photolyase

Explicación

Pregunta 9 de 15

1

A mutation resulting in COPY NUMBER VARIATION can vary between identical twins. Therefore it happens during:

Selecciona una de las siguientes respuestas posibles:

Mitosis
Meiosis
Both of the above
None of the above

Explicación

Pregunta 10 de 15

1

What does the image above show?

Selecciona una o más de las siguientes respuestas posibles:

Gene expression of different members of a gene family varying in different parts of the same plant
Gene expression of different members of a gene family varying in different stages of the same plant's development

Explicación

Pregunta 11 de 15

2

(from end of L06 slides)
Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

Selecciona una o más de las siguientes respuestas posibles:

promoters
introns
5’-UTR
3’-UTR
exons
5’-URT
3’-URT

Explicación

Pregunta 12 de 15

1

Blonde vs brown-hair is an example of variation in:

Selecciona una de las siguientes respuestas posibles:

gene expression
aa sequence
gene splicing

Explicación

Pregunta 13 de 15

2

(from end of L06 slides)
Define a gene family:

Selecciona una de las siguientes respuestas posibles:

A set of several similar genes, formed by duplication of a single original gene
A set of several copies of identical genes, responsible for varying levels of a single trait

Explicación

Pregunta 14 de 15

1

(from end of L06 slides)
What is a pseudogene?

Selecciona una o más de las siguientes respuestas posibles:

A non-functional copy of a gene including a regulatory mutation that prevents its expression
A non-functional copy of a gene including a premature stop codon within the gene that prevents its expression

Explicación

Pregunta 15 de 15

2

(from end of L06 slides)
What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)

Selecciona una o más de las siguientes respuestas posibles:

Variation in amino acid sequences
Regulatory sequences
Variation in gene number
Variation in splicing
Novel genes

	Creado por Michael Jardine hace alrededor de 6 años

L05 - Mutation and repair: - Errors and repair; - Types of mutations; - Consequences of mutation L06 - Mutation and phenotypic variation: - Phenotypic differences can be obtained by: * Adding sequences to the genome; * Changing sequences or gene expression; * Changing the environment

GEGE2001 Week 03 (L05 & L06)

Pregunta 1 de 15

(from end of L05 slides) In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 2 de 15

(from end of L05 slides) How does a frameshift mutation differ from a missense mutation?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 3 de 15

(from end of L05 slides) Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain *here*, but be ready to)

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 4 de 15

DNA is replicated in:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 5 de 15

UV:

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 6 de 15

Which of the following is NOT a type of DNA mutation (necessarily)?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 7 de 15

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks: Silent mutation: ❌; Missense mutation: ❌; Nonsense mutation: ❌; Frameshift ❌.

Arrastra y suelta para completar el texto.

Explicación

Pregunta 8 de 15

UV repair in humans is through:

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 9 de 15

A mutation resulting in COPY NUMBER VARIATION can vary between identical twins. Therefore it happens during:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 10 de 15

What does the image above show?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 11 de 15

(from end of L06 slides) Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 12 de 15

Blonde vs brown-hair is an example of variation in:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 13 de 15

(from end of L06 slides) Define a gene family:

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 14 de 15

(from end of L06 slides) What is a pseudogene?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 15 de 15

(from end of L06 slides) What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)

Selecciona una o más de las siguientes respuestas posibles:

Explicación

(from end of L05 slides)
In a particular cell, a non Watson-Crick base pair (T-G) is formed during DNA replication. What is likely to happen next?

(from end of L05 slides)
How does a frameshift mutation differ from a missense mutation?

(from end of L05 slides)
Did the fluctuation test show that bacterial cells induce mutation upon exposure to the selective agent (viral infection)? Explain. (well, don’t explain here, but be ready to)

Types of mutations AT THE PROTEIN-CODING LEVEL. Fill in the blanks:
Silent mutation: ❌;
Missense mutation: ❌;
Nonsense mutation: ❌;
Frameshift ❌.

(from end of L06 slides)
Variation in gene regulation = mutations that alter the amount of protein product, without a chance in the amino acid sequence. Basically a regulatory mutation. This can be in which of the following:

(from end of L06 slides)
Define a gene family:

(from end of L06 slides)
What is a pseudogene?

(from end of L06 slides)
What are the 2 most likely sources of phenotypic and genomic variation between individuals within a species? (…excluding environmental factors for some reason)