Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Pregunta 1 de 20

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There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

Explicación

Pregunta 2 de 20

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The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

Explicación

Pregunta 3 de 20

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Na flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Ca flows inwards, causing ( depolarisation, hyperpolarisation ) which is ( excitatory, inhibitory )
Cl flows inwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )
K flows outwards, causing ( hyperpolarisation, depolarisation ) which is ( inhibitory, excitatory )

Explicación

Pregunta 4 de 20

1

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Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

Explicación

Pregunta 5 de 20

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Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

Explicación

Pregunta 6 de 20

1

Events at the Synapse are mostly mediated by means of ..

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Calcium Channels
Sodium Channels
Potassium Channels
Chlorine Channels

Explicación

Pregunta 7 de 20

1

There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

Arrastra y suelta para completar el texto.

Ionotropic Receptor

Metabotropic Receptor

Synapotropic Receptor

Explicación

Pregunta 8 de 20

1

Label the receptor types shown in the diagram below.

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Ionotropic Receptors

Synapotropic Receptors

Metabotropic Receptors

Explicación

Pregunta 9 de 20

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The major excitatory neurotransmitter is ...

Selecciona una de las siguientes respuestas posibles:

GABA
Glutamate
Glycine
Dopamine

Explicación

Pregunta 10 de 20

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However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

Explicación

Pregunta 11 de 20

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Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

Explicación

Pregunta 12 de 20

1

The major inhibitory neurotransmitter is ...

Selecciona una de las siguientes respuestas posibles:

Glutamine
GABA
Glycine
Dopamine

Explicación

Pregunta 13 de 20

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As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Explicación

Pregunta 14 de 20

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Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

Explicación

Pregunta 15 de 20

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❌ Receptors are faster and act simply as 'on-off' switches for channels

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Ionotropic

Metabotropic

Explicación

Pregunta 16 de 20

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❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

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Excitatory Post-Synaptic Potential (EPSP

Inhibitory Post-Synaptic Potential (IPSP

Explicación

Pregunta 17 de 20

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A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Selecciona una de las siguientes respuestas posibles:

An Almost There Potential
A Graded Potential
A Median Potential
A Charted Potential

Explicación

Pregunta 18 de 20

1

Rellena el espacio en blanco para completar el texto.

Which neurotransmitter are excitatory neurons most likely to release?

Explicación

Pregunta 19 de 20

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Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )

Explicación

Pregunta 20 de 20

1

Label the diagram below relating to cells of the cerebellum.

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Mossy Fibre

Granule Cell

Stellate Cell

Purkinje Cell

Basket Cell

Parallel Fibres

Climbing Fibre

	Creado por Matthew Coulson hace casi 6 años

Excitatory and Inhibitory Neurotransmission in the CNS given on 4/9/2018

Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Physiology III: Excitatory and Inhibitory Neurotransmission in the CNS

Pregunta 1 de 20

Selecciona la opción correcta de los menús desplegables para completar el texto.

There is a higher concentration of sodium potassium( sodium, potassium ) on the outside of the cell and potassium sodium( potassium, sodium ) inside the cell

Explicación

Pregunta 2 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

The is a significantly higher lower( higher, lower ) concentration of Calcium extracellularly.

Explicación

Pregunta 3 de 20

Selecciona la opción correcta de los menús desplegables para completar el texto.

Explicación

Pregunta 4 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory? Inhibitory Excitatory Neither( Inhibitory, Excitatory, Neither )

Explicación

Pregunta 5 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory? Excitatory Inhibitory( Excitatory, Inhibitory )

Explicación

Pregunta 6 de 20

Events at the Synapse are mostly mediated by means of ..

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 7 de 20

There are two types of receptors upon which neurotransmitters can act. ❌: Direct gating, whereby the receptor is an integral part of the channel it controls ❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

Arrastra y suelta para completar el texto.

Explicación

Pregunta 8 de 20

Label the receptor types shown in the diagram below.

Arrastra la opción correcta a cada uno de los puntos naranjas

Explicación

Pregunta 9 de 20

The major excitatory neurotransmitter is ...

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 10 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

However, Glutamate can sometimes also elicit inhibitory effects via metabotropic ionotropic( metabotropic, ionotropic ) glutamate receptors

Explicación

Pregunta 11 de 20

Selecciona la opción correcta de los menús desplegables para completar el texto.

Ionotropic Glutamate Receptors: NMDA receptors mediate slow fast( slow, fast ) excitatory synaptic transmission in the CNS Non-NMDA receptors mediate fast slow( fast, slow ) excitatory synaptic transmission in the CNS

Explicación

Pregunta 12 de 20

The major inhibitory neurotransmitter is ...

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 13 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions. Potassium & Chlorine Potassium & Sodium Sodium & Chlorine Sodium & Calcium( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Explicación

Pregunta 14 de 20

Selecciona la opción correcta de los menús desplegables para completar el texto.

Ionotropic GABA receptors tend to mediate Chlorine channels Potassium channels( Chlorine channels, Potassium channels ) Metabotropic GABA receptors tend to mediate Potassium channels Chlorine channels( Potassium channels, Chlorine channels )

Explicación

Pregunta 15 de 20

❌ Receptors are faster and act simply as 'on-off' switches for channels

Arrastra y suelta para completar el texto.

Explicación

Pregunta 16 de 20

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters. ❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Arrastra y suelta para completar el texto.

Explicación

Pregunta 17 de 20

A change in resting membrane potential caused by EPSP or IPSP that is not of sufficient magnitude to cross the threshold for an action potential is called ...

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 18 de 20

Rellena el espacio en blanco para completar el texto.

Which neurotransmitter are excitatory neurons most likely to release?

Explicación

Pregunta 19 de 20

Selecciona la opción correcta del menú desplegable para completar el texto.

Neurotransmitters are released in discrete packages called Quanta Bundles Quota( Quanta, Bundles, Quota )

Explicación

Pregunta 20 de 20

Label the diagram below relating to cells of the cerebellum.

There is a higher concentration of ( sodium, potassium ) on the outside of the cell and ( potassium, sodium ) inside the cell

The is a significantly ( higher, lower ) concentration of Calcium extracellularly.

Based on the previous question, will a drug that acts as a Na channel antagonist be excitatory or inhibitory?
( Inhibitory, Excitatory, Neither )

Based on the previous question, will a drug that acts as a Potassium channel antagonist be excitatory or inhibitory?
( Excitatory, Inhibitory )

There are two types of receptors upon which neurotransmitters can act.
❌: Direct gating, whereby the receptor is an integral part of the channel it controls
❌: Indirect gating, whereby the receptor and the channel it controls are distinct from one another.

However, Glutamate can sometimes also elicit inhibitory effects via ( metabotropic, ionotropic ) glutamate receptors

Ionotropic Glutamate Receptors:
NMDA receptors mediate ( slow, fast ) excitatory synaptic transmission in the CNS
Non-NMDA receptors mediate ( fast, slow ) excitatory synaptic transmission in the CNS

As GABA is an inhibitory Neurotransmitter, it tends to mediate which of the following ions.
( Potassium & Chlorine, Potassium & Sodium, Sodium & Chlorine, Sodium & Calcium )

Ionotropic GABA receptors tend to mediate ( Chlorine channels, Potassium channels )
Metabotropic GABA receptors tend to mediate ( Potassium channels, Chlorine channels )

❌): Depolarising change in resting membrane potential caused by actions of neurotransmitters.
❌): Hyperpolarising change change in resting potential caused by actions of neurotransmitters.

Neurotransmitters are released in discrete packages called ( Quanta, Bundles, Quota )