Calcium and Phosphate balance

What are the main functions of calcium in the body? (6)

In which forms does phosphate exist in the body?

What are the functions of Pi? (5)

How is calcium distributed in the body?

What is the distribution of phosphate in the body?

Which processes determine the net balance of calcium and phosphate in the body? (4)

What is 'corrected calcium' on a blood test?

The bones act as a __________ of calcium

What causes the storage of calcium/phosphate in bones and what causes its removal from bone?

What causes osteoclasts to be differentiated from stem cells?

What are the general actions of PTH? (2)

How does PTH work to increase calcium release from bone?

How is secretion of PTH contolled? (2)

Where else can calcium sensing receptors (CaSRs) be found and what is their action? (2)

What is the main function of vitamin D?

How does vitamin D achieve this?

In bone, there are VDRs on _______________, which stimulate the _____________ of calcium to the bone for ________________.

What other 2 actions does vitamin D have?

What does FGF-23 do?

What is the name of the endogenous, inactive form of vitamin D and where is it found?

How is it made?

What happens to the cholecalciferol next?

What happens to 25-hydroxyvitamin D3?

What controls the synthesis of vitamin D? (3)

What are the consequences of vitamin D deficiency? (3)

What is calcitonin?