Matthew Coulson
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Neurobiology of Addiction lecture given on 05/10/2018

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Matthew Coulson
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Neurobiology of Addiction

Pregunta 1 de 9

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Rellena los espacios en blanco para completar el texto.

The reward pathway, in the most basic sense, begins in the floor of the midbrain at the (clue: VTA), which then projects to the . This structure then projects finally to the cortex.

Explicación

Pregunta 2 de 9

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The reward pathway is also known as the

Selecciona una de las siguientes respuestas posibles:

  • Mesolimbic Pathway

  • Mesocortical Pathway

  • Nigrostriatal Pathway

  • Tuberoinfundibular Pathway

Explicación

Pregunta 3 de 9

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The mesolimbic pathway is one of the four ...

Selecciona una de las siguientes respuestas posibles:

  • Dopaminergic Pathways

  • Adrenergic Pathways

  • Glutamatergic Pathways

Explicación

Pregunta 4 de 9

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In terms of the nucleus accumbens, overexpression of which gene transcription factor is thought to be the main influencer of addiction?

Selecciona una de las siguientes respuestas posibles:

  • ΔFosB

  • ΔJunD

  • cAMP

  • CREB

  • NFκB

Explicación

Pregunta 5 de 9

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Patients showing addictive behaviours tend to have a preserved insight; they know they are unwell.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 6 de 9

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Dopamine release usually has the ability to update info and set new goals in the prefrontal cortex, thus having the ability to avoid compulsive repetition of a behaviour. Addictive drugs provide a potent dopamine signal which disrupts the normal dopamine learning pathway in the prefrontal cortex.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 7 de 9

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On average, those who start experimenting with drugs earlier in life tend to have a shorter relationship with drugs.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 8 de 9

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Which part of the frontal cortex concerns the following:
Emotion and reward in decision making; hyperactivity of this area during addiction behaviour represents craving

Selecciona una de las siguientes respuestas posibles:

  • Orbitofrontal Cortex

  • ‎Ventrolateral Prefrontal Cortex

  • ‎Dorsolateral Prefrontal Cortex

Explicación

Pregunta 9 de 9

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Selecciona la opción correcta de los menús desplegables para completar el texto.

In ( non-addicted, addicted ) brains, areas such as the Anterior Cingulate Gyrus send inhibitory signals to the orbitofrontal cortex and thus the sensation of craving ( does not, does ) occur.
In ( addicted, non-addicted ) brains, the nucleus accumbens sends inhibitory signals to areas such as the Anterior Cingulate Gyrus so that the inhibitory signals are not sent to the Orbitofrontal cortex and thus the sensation of craving ( does, does not ) occur

Explicación