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( Melanin, Lipofuscin, Hemosiderin, Bile ) is Argentaffin and Schmorles positive, DiPAS negative and removed by H2O2 bleach. It is Long ZN negative, fat stain and Luxol Fast Blue negative. ( Lipofuscin, melanin, hemosiderin, bile ) on the other hand can be positive or negative Argentaffin and Schmorle's depending on timing, DiPAS positive, H2O2 bleach does not remove it, and positive for Long ZN, fat stains and Luxol fast blue.