Why enzyme used?

Ribozymes

Types of Enzyme

Prosthetic group

Cofactors

Coenzymes

How enzymes work

Transition state

Catalysis

Lock and key

Induced Fit

Rate depends on,,,

Km

Michaelis menten equation

Kd

K3

Kcat/Km

Notable Kcat

Linwever Burk Equation

Units of activity

How do enzymes work?

Features of enzymes

Lysozyme

Structure of peptidoglycan links

How lysozyme works

Amino acid action

Old mechanism

New mechanism

General principles of enzyme catalysis

Geometric effects

Nucleophilic attack

Acid catalysis

Electrostatic effects

Molecular recognition

Competitive inhibitors

Irreversible Inhibition

Other inhibitors

Reversible covalent modification

Genetic Control

Activation of zymogens

Allosteric Enzymes

Allosteric activators/ inhibitors

Phosphofructokinase

Cooperative binding

Compartmentation