Breast Pathology II

Pregunta 1 de 37

1

Breast Carcinoma is considered to be which type of carcinoma?

Selecciona una de las siguientes respuestas posibles:

Adenocarcinoma
Basal cell carcinoma
Squamous cell carcinoma
Transitional cell carcinoma

Explicación

Pregunta 2 de 37

1

Breast Adenocarcinoma commonly occurs in the epithelial cells of which breast structure?

Selecciona una de las siguientes respuestas posibles:

Terminal Duct Lobular Units
Lactiferous Ducts
Areola
Lactiferous Sinus
Breast Vascular Tissues

Explicación

Pregunta 3 de 37

1

Rellena los espacios en blanco para completar el texto.

A carcinoma which hasn't yet breached basement membrane is known as an carcinoma
A carcinoma which has breached the basement membrane is known as an carcinoma

Explicación

Pregunta 4 de 37

1

Lobular neoplasias:
❌ = >50% of lobule involved
❌ = <50% of lobule involved
❌ = Typically >50% of lobule involved & breach of basement membrane

Arrastra y suelta para completar el texto.

Invasive Carcinoma

Atypical Lobular Hyperplasia

Lobular Carcinoma in situ

Atypical Lobular Hypertrophy

Explicación

Pregunta 5 de 37

1

Rellena el espacio en blanco para completar el texto.

Lobular neoplasms typically grow in response to which hormone?

Explicación

Pregunta 6 de 37

1

The red dots show tumours in a breast. Which shows a multifocal cancer and which shows a multicentric cancer?

Arrastra la opción correcta a cada uno de los puntos naranjas

multifocal

multicentric

Explicación

Pregunta 7 de 37

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

Description of a Lobular In Situ Neoplasia:
Frequently ( multifocal, multicentric, unifocal ) and ( bilateral, unilateral )
Incidence ( decreases, increases ) following menopause
( Is not, Is ) typically palpable
Usually ( incidental, non-incidental ) finding

Explicación

Pregunta 8 de 37

1

How are lobular neoplasms typically managed?

Selecciona una de las siguientes respuestas posibles:

Excision following diagnosis
Reassurance and watchful waiting

Explicación

Pregunta 9 de 37

1

A woman has a routine mammography scan conducted as part of the breast screening program. Three small lesions are noticed in the upper outer quadrant of her right breast. If you were to suggest a biopsy of these lesions, which 2 of the following might you consider?

Selecciona una o más de las siguientes respuestas posibles:

Core Needle Biopsy
Vacuum Needle Biopsy
Fine Needle Aspiration
Immediate Surgical Excision of Lesions

Explicación

Pregunta 10 de 37

1

In which breast structures do Ductal Carcinoma In Situ originate?

Selecciona una de las siguientes respuestas posibles:

Terminal Duct Lobular Unit
Lactiferous Duct
Lactiferous Sinus
Sub-areolar structures
Breast Vasculature

Explicación

Pregunta 11 de 37

1

Ductal carcinoma in situ is typically ❌

Arrastra y suelta para completar el texto.

unicentric (affects single duct system)

multicentric (multiple duct systems)

Explicación

Pregunta 12 de 37

1

❌ = Confined within the basement membrane of the duct
❌ = Breached the basement membrane of the duct

Arrastra y suelta para completar el texto.

Invasive Ductal Carcinoma

Ductal Carcinoma in situ

Explicación

Pregunta 13 de 37

1

Rellena el espacio en blanco para completar el texto.

Observe the picture. Which condition are you worried about in this woman?
of the breast

Explicación

Pregunta 14 de 37

1

Selecciona la opción correcta del menú desplegable para completar el texto.

Paget's Disease of the Breast is typically indicative of an underlying ( Ductal Carcinoma In Situ, Invasive Ductal Carcinoma )

Explicación

Pregunta 15 de 37

1

Which of the following are typical signs of Paget's Disease of the Breast?

Selecciona una o más de las siguientes respuestas posibles:

Involuted nipple
Straw-coloured/bloody discharge from nipple
Burning pain sensation in nipple
Eczema on the nipple
Low hanging breast on affected side

Explicación

Pregunta 16 de 37

1

Rellena el espacio en blanco para completar el texto.

In the case of high grade ductal neoplasms such as DCIS, growth of the tumour can outpace the development of the blood supply thus leading to the entire duct becoming plugged with cancerous cells which typically become necrosed. This is known as necrosis.

Explicación

Pregunta 17 de 37

1

How is Ductal Carcinoma In Situ typically managed?

Selecciona una de las siguientes respuestas posibles:

Surgical excision +/- radiotherapy
Reassurance & watchful waiting
Core Needle/Vacuum Biopsy to exclude invasive carcinoma then radiotherapy only

Explicación

Pregunta 18 de 37

1

Rellena el espacio en blanco para completar el texto.

Which structure is breached in invasive carcinomas?
The

Explicación

Pregunta 19 de 37

1

Breast cancer is the most commonly diagnosed cancer in females

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 20 de 37

1

Rellena el espacio en blanco para completar el texto.

Which cancer most commonly affects males?
cancer

Explicación

Pregunta 21 de 37

1

Having a child which a woman subsequently breast feeds significantly reduces her risk of developing breast cancer at a later age.

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 22 de 37

1

Nulliparous women are less likely to develop breast cancer

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 23 de 37

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

Risk Factors for Breast Cancer Development:
( Early, Late ) menarche
( Late, Early ) menopause

Explicación

Pregunta 24 de 37

1

Hormone therapies such as HRT and the Oral Contraceptive Pill have negligible effects on the risk of breast cancer development

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 25 de 37

1

Women in Western Europe have the highest incidence of breast cancer of any geographical region in the world.

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 26 de 37

1

Which of the following has a greater impact on the risk of breast cancer development?

Selecciona una de las siguientes respuestas posibles:

Cigarette Smoking
High Alcohol Consumption

Explicación

Pregunta 27 de 37

1

Selecciona la opción correcta del menú desplegable para completar el texto.

Which genetic mutations are the most common indicators of breast cancer risk in women?
( BRCA, BCRF, BCAG ) mutations 1 and 2

Explicación

Pregunta 28 de 37

1

Selecciona la opción correcta del menú desplegable para completar el texto.

Statistically, 1 in every ( 8, 6, 12, 20 ) women will develop breast cancer at some point in their lifetime.

Explicación

Pregunta 29 de 37

1

Which of the following is the most common invasive breast carcinoma?

Selecciona una de las siguientes respuestas posibles:

Ductal
Lobular
Tubular
Mucinous
Medullary

Explicación

Pregunta 30 de 37

1

Which of the following is the second most common invasive breast carcinoma?

Selecciona una de las siguientes respuestas posibles:

Ductal
Lobular
Mucinous
Tubular
Medullary

Explicación

Pregunta 31 de 37

1

Which lymph nodes do breast carcinomas typically metastasize to?

Selecciona una de las siguientes respuestas posibles:

Axillary
Para-aortic
Abdominal
Internal Mammary
Supraclavicular

Explicación

Pregunta 32 de 37

1

Rellena el espacio en blanco para completar el texto.

The lymph node is the hypothetical first lymph node or group of nodes in which a tumour drains.

Explicación

Pregunta 33 de 37

1

The more hormone receptors an invasive carcinoma has, the better its prognosis.

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 34 de 37

1

In terms of hormone receptors, 80% of invasive breast carcinomas are positive for ❌ receptors and 67% are positive for ❌ receptors

Arrastra y suelta para completar el texto.

progesterone

oestrogen

Explicación

Pregunta 35 de 37

1

Rellena el espacio en blanco para completar el texto.

is an anti-oestrogen prodrug which when given gives rise to compounds which act as oestrogen receptor antagonists, thus preventing the growth and proliferation of cancer cells.

Explicación

Pregunta 36 de 37

1

Tamoxifen should not be given to those with non-invasive breast cancer (e.g. DCIS)

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 37 de 37

1

The primary treatment for invasive breast cancers such as Invasive Ductal Carcinoma is hormone adjuvant therapy

Selecciona uno de los siguientes:

VERDADERO
FALSO

	Creado por Matthew Coulson hace casi 6 años

Breast apthology II lecture given on the morning of tuesday 8th January

Breast Pathology II

Breast Pathology II

Pregunta 1 de 37

Breast Carcinoma is considered to be which type of carcinoma?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 2 de 37

Breast Adenocarcinoma commonly occurs in the epithelial cells of which breast structure?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 3 de 37

Rellena los espacios en blanco para completar el texto.

A carcinoma which hasn't yet breached basement membrane is known as an carcinoma A carcinoma which has breached the basement membrane is known as an carcinoma

Explicación

Pregunta 4 de 37

Lobular neoplasias: ❌ = >50% of lobule involved ❌ = <50% of lobule involved ❌ = Typically >50% of lobule involved & breach of basement membrane

Arrastra y suelta para completar el texto.

Explicación

Pregunta 5 de 37

Rellena el espacio en blanco para completar el texto.

Lobular neoplasms typically grow in response to which hormone?

Explicación

Pregunta 6 de 37

The red dots show tumours in a breast. Which shows a multifocal cancer and which shows a multicentric cancer?

Arrastra la opción correcta a cada uno de los puntos naranjas

Explicación

Pregunta 7 de 37

Selecciona la opción correcta de los menús desplegables para completar el texto.

Explicación

Pregunta 8 de 37

How are lobular neoplasms typically managed?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 9 de 37

A woman has a routine mammography scan conducted as part of the breast screening program. Three small lesions are noticed in the upper outer quadrant of her right breast. If you were to suggest a biopsy of these lesions, which 2 of the following might you consider?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 10 de 37

In which breast structures do Ductal Carcinoma In Situ originate?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 11 de 37

Ductal carcinoma in situ is typically ❌

Arrastra y suelta para completar el texto.

Explicación

Pregunta 12 de 37

❌ = Confined within the basement membrane of the duct ❌ = Breached the basement membrane of the duct

Arrastra y suelta para completar el texto.

Explicación

Pregunta 13 de 37

Rellena el espacio en blanco para completar el texto.

Observe the picture. Which condition are you worried about in this woman? of the breast

Explicación

Pregunta 14 de 37

Selecciona la opción correcta del menú desplegable para completar el texto.

Paget's Disease of the Breast is typically indicative of an underlying Ductal Carcinoma In Situ Invasive Ductal Carcinoma( Ductal Carcinoma In Situ, Invasive Ductal Carcinoma )

Explicación

Pregunta 15 de 37

Which of the following are typical signs of Paget's Disease of the Breast?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 16 de 37

Rellena el espacio en blanco para completar el texto.

In the case of high grade ductal neoplasms such as DCIS, growth of the tumour can outpace the development of the blood supply thus leading to the entire duct becoming plugged with cancerous cells which typically become necrosed. This is known as necrosis.

Explicación

Pregunta 17 de 37

How is Ductal Carcinoma In Situ typically managed?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 18 de 37

Rellena el espacio en blanco para completar el texto.

Which structure is breached in invasive carcinomas? The

Explicación

Pregunta 19 de 37

Breast cancer is the most commonly diagnosed cancer in females

Selecciona uno de los siguientes:

Explicación

Pregunta 20 de 37

Rellena el espacio en blanco para completar el texto.

A carcinoma which hasn't yet breached basement membrane is known as an carcinoma
A carcinoma which has breached the basement membrane is known as an carcinoma

Lobular neoplasias:
❌ = >50% of lobule involved
❌ = <50% of lobule involved
❌ = Typically >50% of lobule involved & breach of basement membrane

❌ = Confined within the basement membrane of the duct
❌ = Breached the basement membrane of the duct

Observe the picture. Which condition are you worried about in this woman?
of the breast

Paget's Disease of the Breast is typically indicative of an underlying ( Ductal Carcinoma In Situ, Invasive Ductal Carcinoma )

Which structure is breached in invasive carcinomas?
The

Which cancer most commonly affects males?
cancer

Risk Factors for Breast Cancer Development:
( Early, Late ) menarche
( Late, Early ) menopause

Which genetic mutations are the most common indicators of breast cancer risk in women?
( BRCA, BCRF, BCAG ) mutations 1 and 2

Statistically, 1 in every ( 8, 6, 12, 20 ) women will develop breast cancer at some point in their lifetime.