The primary excitatory neurotransmitter is ______, and ______ is the primary inhibitory neurotransmitter.
GABA, Glutamate
Glutamate, GABA
Dopamine, Serotonin
Adrenaline, Opiate
An agonist is a drug that...
Is always less potent than an antagonist
Elicits a similar physiological response to that of a neurotransmitter
Will usually have depressant effects
All of the above
The anti-depression drug Fluoxetine (also known as Prozac) increases level of serotonin. It does this by...
increasing serotonin production
inhibiting serotonin deterioration
indirect stimulation of serotonic cells
blocking the reuptake of synaptic serotonin
An increase in _____ for a drug would cause that drug to more rapidly reach the brain.
Metabolism of the drug via the liver
Lipid solubility
Water solubility
Kidney excretion
One mechanism for the tolerance produced by repeated drug administration is...
A decreased metabolism of the drug
An increased plasma level of the drug
An increased number of receptors for the drug
A reduced number of receptors for the drug
Caffeine acts to...
Block adenosine receptors
Stimulate adenosine receptors
Block noradrenaline receptors
Block acetylcholine receptors
The psychoactive constituent of the drug cannabis (THC) probably acts on the same receptors as...
Adenosine
Anandamide
Adenylate cyclase
Arachidonic cannabinol
Naloxone would be effective at reversing the effects of...
Dextro-amphetamine
LSD
Morphine
Both LSD and Morphine
Repeated administration of barbiturates/opiates may cause no increase in level of sedation/pain relief but an increasing effect on respiratory depression. Why might this be?
The drug begins to act as a placebo
The drug has an increased margin of safety over time
The drug has more than one site of action
The drug binds with an ionotropic receptor
Drugs that are postsynaptic receptor antagonists...
Increase neural inhibition only
Reduce neural inhibition only
Increase or reduce neural inhibition depending on the typical action of the neurotransmitter
Increase neural inhibition only when bound to a metabotropic receptor
A drug which prevents the storage of a neurotransmitter within synaptic vesicles would be...
An agonist
An antagonist
Either an agonist or an antagonist
An agonist only when calcium channels are open
If a drug blocks pre-synaptic transporter reuptake molecules, then it is...
An agonist only when sodium channels are open
Repeated stimulation of the mesolimbic system can lead to drug abuse. This is because...
This system projects to the prefrontal cortex
This system is important for reinforcement
This is an important part of the basal ganglia
This system is important in the control of the mood
GABA receptors are complex, but it is known that alcohol will act as...
An agonist to these receptors
An antagonist to these receptors
Either an agonist or an antagonist to these receptors
An agonist but only if steroid molecules are also bound to the receptor
Why might terahydrocannabinol (THC), the active ingredient in marijuana) be used by people taking certain drugs for cancer?
It reduces anxiety produced by cancer drugs
It acts as an antagonist for the neurotransmitter anandamide
It reduces nausea produced by cancer drugs
