Antimicrobial Concepts

What are the four quadrants of spectrum?

What is the mechanism of action of bacteriostatic drugs?

How do bacteriostatic drugs react with other drugs?

What is the mechanism of action of bactericidal drugs?

Why can bactericidals cause superinfections?

What is the process of a Kirby Bauer test?

Why might a 96-well Format Microtiter Plate be a better test than Kirby Bauer when determining sensitivity?

Explain the use and process of an E-test

What data is needed to establish a a breakpoint?

What are reasons an organism may be intrinsically resistant to a drug?

Why might an antimicrobial be placed into group D?

List the 6 basics of antibiogram design

What is the value of MIC90 Tables?

What 3 types of antimicrobial
agents work by inhibiting
cell wall synthesis?

What are narrow spectrum
penicillins?

What are common
aminopenicillins?

What are common penicillinase-resistant / antistaphylococcal
penicillins?

What are common extended
spectrum penicillins?

What are common
B-lactamase inhibitors?

What is a common carbapenem?

What is a common monobactem?

What is the MoA of penicillin?

Are B-lactams bacteriostatic or bactericidal?

Why are B-lactamase inhibitors combined with penicillin?

What is the MoA of Carbapenems?

When are monobactams used?

Give common 1st and 3rd generation cephalosporins

How do cephalosdporins compare to penicillins?

What drugs are inhibitors of ribosomal 30s subunit?

What drugs are inhibitors of ribosomal 50S subunit?

What are common macrolides?

Are macrolides bacteriostatic or bactericidal?

What are common types of Lincosamides?