THE CELL CYCLE, MITOSIS AND CANCER BIOL2

What are the two main stages of cell division?

What are the two types of nuclear division?

What is the name given to the method of DNA replication that is universally accepted?

What are the 4 requirements for semi-conservative replication to take place?

In the semi-conservative method, which enzyme acts first and what does it do?

What does this result in?

What do these polynucleotide strands than act as?

What is required to activate these free nucleotides?

How are the activated nucleotides jointed to their complementary base pair?

What does this form?

So, what do each of the new DNA molecules contain?

Which two scientists conducted an experiment to test the hypothesis of the semi-conservative method?

Which three facts did they base their work on?

They reasoned that bacteria growing on a medium containing 14N would be _______than bacteria grown on a medium containing 15N

They labelled the 'old' DNA by _______ __ __ _ _______ __ ____

Where did they then transfer the bacteria and what did they allow it to do?

What would the mass of each new DNA molecule depend on?

How did they separate the different DNA types?

Where did the ligher DNA collect and where did the heavier DNA collect?

What is the definition of mitosis?

In which rare event may the daughter cells NOT have identical DNA to the parent cell?

What is name given to the period of time before mitosis in which the cell is not dividing?

What important process occurs during interphase?

Mitosis is continuous process but it can be divided into 4 stages. What are these four stages?

What happens during prophase?

What happens during metaphase?

What happens during anaphase?

What reforms during telophase?

And then what follows?

What are the three main reasons mitosis is important?

What are the three stages of the cell cycle?

Interphase occupies most of the cell cycle. What are the three parts of interphase?

What is G1?

What happens during S phase?

What happens during G2 phase?

What happens during nuclear division?

By what process does the nucleus divide into 2?

How many does the nucleus divide into during meiosis?

What is cancer?

Cancer is result of damage to what?

What does this lead to?

How do drugs used to treat cancer (chemotherapy) disrupt the cell cycle?

What drugs can be used to prevent DNA from replicating?

What drug can be used to inhibit metaphase by interfering with spindle formation?

What is the problem with such drugs?

However why are cancer cells damaged to a greater degree than normal cells?