BIOCHEMISTRY: Intermediate metabolism

1

A low level of carbon dioxide labeled with 14C is accidentally released into the atmosphere surrounding industrial workers as they resume work following the lunch hour. Unknowingly, they breathe the contaminated air for 1 hour. Which of the following compounds will be radioactively labeled?

1

A teenager, concerned about his weight, attempts to maintain a fat-free diet for a period of several weeks. If his ability to synthesize various lipids were examined, he would be found to be most deficient in his ability to synthesize:

1

A 44-year-old man displayed elevated cholesterol levels and was prescribed a statin to reduce such levels. Statin treatment has the potential to interfere with the synthesis of which of the following?

1

A 12-year-old female presented with severe abdominal pain and was found to have a markedly elevated plasma triglyceride concentration (750 mg/dL). A lipoprotein analysis revealed elevated levels of chylomicrons and VLDL and reduced levels of HDL. Which protein might be defective in this patient?

1

Statins are ineffective in lowering cholesterol levels in individuals with homozygous familial hypercholesterolemia due to which of the following?

1

An adult male should have HDL levels equal to or greater than 40 mg/dL. A necessary enzyme contributing to HDL’s protective effect is which of the following?

1

You have placed a patient on Pravachol pravastatin to reduce her cholesterol. This class of drugs is effective due to a direct inhibition of which of the following?

1

A child has been diagnosed with Tay–Sachs disease, in which a particular lipid accumulates within the lysosomes. The component of this lipid which cannot be removed in the lysosome is which of the following?

1

Glutathione is a constituent of

1

Cyclo-oxygenase is involved in the synthesis of

1

Esters of fatty acids with higher alcohols other than glycerol are said to be

1

Carnitine is synthesized from

1

A patient has been diagnosed with abetalipoproteinemia. A possible deficiency in which of the following vitamins could occur in this patient?

1

Which one of the fatty acids listed below can be synthesized by humans?

1

You are treating a patient with a fat malabsorption problem, and you suggest that the patient switch his or her diet to one that contains which of the following?

1

Treatment of dyslipidemia may involve giving the patient one of these

1

The above prescription works by

1

The exchange of cholestrol esters for triacylglycerols between HDLs and VLDLs is catalysed by

1

Tay-Sachs is to hexosaminidase as Gaucher is to__________

1

Non-liver and Non-intestine cells get cholesterol from the plasma, rather than synthesizing it de novo from LDL

Comprehensive Review questions compiled by turknO_ for leggomed

BIOCHEMISTRY: Intermediate metabolism

A low level of carbon dioxide labeled with 14C is accidentally released into the atmosphere surrounding industrial workers as they resume work following the lunch hour. Unknowingly, they breathe the contaminated air for 1 hour. Which of the following compounds will be radioactively labeled?

A teenager, concerned about his weight, attempts to maintain a fat-free diet for a period of several weeks. If his ability to synthesize various lipids were examined, he would be found to be most deficient in his ability to synthesize:

A 44-year-old man displayed elevated cholesterol levels and was prescribed a statin to reduce such levels. Statin treatment has the potential to interfere with the synthesis of which of the following?

A 12-year-old female presented with severe abdominal pain and was found to have a markedly elevated plasma triglyceride concentration (750 mg/dL). A lipoprotein analysis revealed elevated levels of chylomicrons and VLDL and reduced levels of HDL. Which protein might be defective in this patient?

Statins are ineffective in lowering cholesterol levels in individuals with homozygous familial hypercholesterolemia due to which of the following?

An adult male should have HDL levels equal to or greater than 40 mg/dL. A necessary enzyme contributing to HDL’s protective effect is which of the following?

You have placed a patient on Pravachol pravastatin to reduce her cholesterol. This class of drugs is effective due to a direct inhibition of which of the following?

A child has been diagnosed with Tay–Sachs disease, in which a particular lipid accumulates within the lysosomes. The component of this lipid which cannot be removed in the lysosome is which of the following?

Glutathione is a constituent of

Cyclo-oxygenase is involved in the synthesis of

Esters of fatty acids with higher alcohols other than glycerol are said to be

Carnitine is synthesized from

A patient has been diagnosed with abetalipoproteinemia. A possible deficiency in which of the following vitamins could occur in this patient?

Which one of the fatty acids listed below can be synthesized by humans?

You are treating a patient with a fat malabsorption problem, and you suggest that the patient switch his or her diet to one that contains which of the following?

Treatment of dyslipidemia may involve giving the patient one of these

The above prescription works by

The exchange of cholestrol esters for triacylglycerols between HDLs and VLDLs is catalysed by

Tay-Sachs is to hexosaminidase as Gaucher is to__________

Non-liver and Non-intestine cells get cholesterol from the plasma, rather than synthesizing it de novo from LDL