|
Creado por Ifeoma Ezepue
hace casi 9 años
|
|
Define the term pharmacology
How do substances interact with living things?
Define the term drug
Define the term poison
Define the term toxins
Define the term receptor
Define the term agonist
What is the difference between agonists and antagonists?
What happens when the ligand leaves the receptor?
Define the term partial agonist
Define the term efficacy
Define the term affinity
What sort of affinity do partial agonists have for the receptor? Explain the effects of this
Describe how a partial agonist binds to and activates the receptor
Define the term pharmacologic antagonist
State the names of the four different types of pharmacologic antagonist
How does a competitive antagonist work?
How does a non-competitive antagonist work?
How does a chemical antagonist work?
What is a physiologic antagonist?
What are the two ways drugs can be administered?
What two processes follow the distribution of drugs in the body?
Define the terms enteric and efflux
Define the terms intravascular and extravascular
What do drugs tend to be?
What is the difference between the dissociated and un-dissociated form of a drug?
What is meant by the term 'weak' acid? Use aspirin as an example
What is meant by the term pKa?
What are other terms for fat-soluble and water-soluble?
What is TCA? What sort of acid is it? What are two damaging effects of TCA overdose?
What should be done in the event of TCA overdose?
What is activated charcoal?
How can amphetamine excretion be speeded up?
Explain what is meant by drug specificity
Explain what is meant by drug selectivity
What are receptors responsible for - specificity or selectivity of drug action?
Drugs interact with receptors by means of chemical forces or bonds. What are the four different types? Comment on their relative strength also
What is pharmacodynamics?
What is pharmacokinetics?
Explain the shape of a standard dose response curve
What is half of a maximum response?
What's the difference between the shape of a dose response curve with a competitive and non-competitive antagonist?
What is meant by the term potency?
Explain what is meant by 'spare receptors'
What are two functional benefits of spare receptors?
How are spare receptors useful with competitive antagonists?