What is Toxicology?
What is a toxicant?
What is a dose?
Threshold Dose
Dosage rate
Therapeutic Index
Sources of variance in toxic response regarding the animal
Sources of variance in toxic response regarding the exposure
TD50
LD50
toxicokinetics
toxicodynamics
Stabilize CAB in that order
POISONED PATIENT.... ZOMG what do I do?
-On the phone
POISONED PATIENT.... ZOMG what do I do?
-At the hospital
Stabilizing/Supportive Care
•Respiratory
Stabilizing/Supportive Care
•Circulatory
Stabilizing/Supportive Care
•CNS
Stabilizing/Supportive Care
•Body Temp
POISONED PATIENT.... ZOMG what do I do?
-At the hospital decontamination
Induction of emesis at home
induction of emesis at the clinic in cats
Induction of emesis at the clinic in dogs
Gastric lavage
Activated Charcoal
Treatment
When is activated charcoal a good call?
When does activated charcoal perform poorly?
Cathartics
Cathartics- Mineral Oil
Gastrototomy/Endoscopy
Topical Toxins
Detoxification
Forced Dialysis/Diuresis
ion trapping
Antidotes
SLUDGE(M)
Acid Burns
Alkali Burns
General concepts about soaps, detergents, cleaning agents
Soaps
Non-ionic detergents
Anionic Detergents
Anionic Detergents
Tx
Cationic Detergents
General
Cationic Detergents
Symptoms
Cationic Detergents
Tx
Should you give acids to treat cationic detergent toxicity?
Acidic corrosive/caustic cleaning products
Alkali corrosive/caustic cleaning products general
Alkali corrosive/caustic cleaning products treatments
Alkali corrosive/caustic cleaning products symptoms