BioChemistry

Alanine , Valine , Leucine and Isoleucine interact in a special way within proteins

The secondary amino(imino) group of proline residues

Having aromatic side chains helps you do what, Name amino acids with them

The importance of Tyrosine in enzymes

What role do Disulfide Groups play in polypeptide structures ?

Which amino have a significant positive charge at ph 7.0

Which amino acids have a R group with a net negative charge

Name a derivative of proline and where they are found

What is Collagen

Name 4 examples of connective tissue

Name an uncommon Amino Acid derived from lysine and where it is found

Name a derivative of lysine found in myosin and say what myosin is

Name a derivative of Glutamate and its use

The derivative of Four lysine residues and its function

What is Circular Dichroism

What are Chromophores and how do they act in the chiral Envronment

What did Anfisens experiment show

What conformation are favored by proteins

How can proteins fold so fast

Two classes of molecular chaperons

What are Heat Shot Proteins and what do they do

What catalyzes interchange or shuffling of s-s bonds

What catalyzes the interconversion of the cic and trans isomers of proline

What is the characteristic of proteins containing proline

What are Amyloidoses and what are they caused by

Name Amyloid diseases

Name some of these diseases

What is Parkinsons disease

What is Huntington's disease

What is Prion ?

Name some Prions Disease

What is Proteostasis

What are the two major classes of proteins

What is Keratin and is it found

Name two anticoagulants

What is the major difference between Plasma and Serum

Name plasma proteins

What are the two types of Immune systemes

How does the Cellular immune system work

How does the Humoral Immune system work

What are Antigens and Antibodies and how do they relate

What is a epiotope and how does it relate to the immune system

How can Proteins High specifity be explained

What are they complementary in

How can we make Glycoproteins and proteoglycans

What are carbohydrates

What are the three classes of carbohydrates

What are Epimeres

What is the actual function of a buffer system such as acetate/acetic acid

What two weak interactions are most important in the formation of a cluster of lipid molecules in an aqueous solution

How many of the 20 common amino acids have rings in their structures and which ones are they

What results from a condensation reaction between two amino acides, such as Glycine and Alanine

What is the average weight of an amino acide

Which amino acid would most likely be found in the interior of a globular protein

Which functional group is used to form Disulfide bonds

Which type of weak interaction is more important for cohesiveness and strength between beta-strands in beta-sheets

What is the highest level of protein structure in human insulin,

Which amino acid would most likely be found in the interior of a globular protein

Protein folding to a native conformation is highly dependent upon what

What are the four main steps of sequencing a protein

There are two main ways of breaking disulfide bonds name them and the resultant residues

Name the four Reagents for fragmenting polypeptide chains and where do they fragment

Name two sequencing methods

What is the difference between the Edman degradation method and the Sanger's method

Describe the Edmans degradation for peptide sequencing

Name the four favorable interactions within a protein

Why is rotation around the C-N bond restricted for planar peptide groups in polypeptide chain

Why are nearly all peptide groups in proteins in trans conformation

What are dihedral angles

Name four functions filled by Carbohydrates

Is it true that L and D glucose have different solubility levels

Most Hexoses in living organisms are L steriomeres

What are Diastereoisomeres

Name the three D aldoses seen in class and say if they have the same level of solubility

Draw the two glucose epimers seen in class

What compound is found in self tanner lotion and how is it made

Draw Ribose, glucose, galactose, Mannose and Fructose

Between Aldehydes, Ketone carbons and Alcohol oxygens which are nucleophilic and which are electrophilic

What are Hemiacetals and Hemiketals and how are they formed

what are six membered oxygen containing rings called and draw three

What are five membered oxygen containing rings called

What can carbohydrates be covalently bonded with ?

Give an example of a dissacharide that is 1. A Ketone 2. A polyhydroxyl aldehyde

How can bonds between carbohydrates be 1. Broken 2. synthesized

Name three 3 common disaccharides

Name important Haxose Derivatives 6 in the course

Glycosidic bonds in carbohydrates are between

In gycosidic linkages which elements are reducing or non reducing

Where in nature can trehalose be found in nature and what disease in humans could it be used to treat

Name two oligosaccharides that are components of antibiotics

Natural carbohydrates can be found as polymers, these polysaccharides can be of different types. Which ones

Name three heteropolysaccharides

What type of polysaccharide is glycogen