Generally speaking, everything shrinks in the elderly except the prostate. People also get more brittle and stiff.

The elderly tend to have difficulty seeing at night due to reductions in pupil reflex and thinning of the lens itself. An amber tint will also develop.

Only 1/3 of aging is inevitable but we have some control over the other 2/3rds. We lose a base of 1% organ reserve per year after completion of development.

Which of the following is false?

Blood vessels in the brain thin with aging. Generally speaking cognitive ability of the brain doesn't decline in function as readily as other organ systems and loss of individual neurons begins at a more advanced age (~60).

Generally speaking aging includes slowed reflexes and responses to stimuli somewhere between 30-70%. This includes baroreceptor sensitivity resulting in hypotension on standing because of impaired blood pressure response and hypertrophy of the left ventricular wall.

APOE e4 is the gene associated with Alzheimer's disease. Diabetes and Athersclerosis have also been associated with steeper than expected declines in cognitive ability.

Serum creatinine concentration is not affected by aging. Creatinine production decreases with age.

Which of the following does not change with age?

Which of the following has the greatest deleterious velocity of change in aging?