What is MHC?
Presents antigens to T-cell on antigen presenting cells
Receives antigens from T-cells to antigen presenting cells
TCR's- T Cell Receptors that detect antigens presented by antigen presenting cells
Presentation of antigens through MCH/TCR activates the T-cell
How to Superantigens work?
Increase the presentation of antigens by MHC, super-stimulating the T-cells
Allows MHC/TCR binding without antigen present, super-stimulating the T-cells
Prevents T cell activation by destroying TCR's
Why are Superantigens dangerous
They prevent T-Cell activation
The over-activate T-Cells
Which causes T-Cells to over-release cytokins, causing shock like symptoms
Exotoxins are secreted during cell lysis
Which of the following are capable of producing Endotoxins?
Gram +ve
Gram -ve
What happens to exotoxins?
They're secreted during cell lysis
They secreted during normal cell function
They're expressed on the cell surface
Exotoxins tend to be produced by Gram +ve bacteria
