DR is a 40-year-old man admitted for confusion and altered mental status. His physical exam is unremarkable. His vital signs are stable with a heart rate of 80 BPM, respiratory rate of 14 BPM, and blood pressure of 120/70 mm Hg. DR’s past medical history is includes only a long standing history of depression, currently treated with paroxitine controlled release 50 mg PO daily. DR weighs 82 kg. His admission labs show a Na 119 mEq/L (normal 136–146), K 3.6 mEq/L (normal 3.5–5.2), Cl 100 mEq/L (normal 100–110), CO2 32 mEq/L (normal 21–33), BUN 7 mg/dl (normal 7–23), glucose
80 mg/dl (normal 70–110), albumin 2.4 g/dl (normal 3.2–4.8), Ca 9.2 mEq/L (normal 8.8–10.5), magnesium 2.0 mEq/L (normal 1.6–2.2), Phos 4.1 mmol/L (normal 2.4–4.3). DR’s doctor orders additional labs to evaluate the hyponatremia. The results are as follows. A spot urine sodium is 22 mEq/L and urine osmolality is 180 mOsm/L. Which one of the following is the best initial treatment for DR’s hyponatremia?
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