Increased cholesterol and LDLs is a risk factor for CAD
Statins lower LDL's for both primary and secondary prevention
Which of the following is NOT a sign of high cholesterol
Corneal Acrhus
Tendon Xantheromas
Lactescent Plasma
Lipidemia Retinalis
Xantheolisma
Most people won't show signs of hyperlipidemia
Many with Cardiac Infarctions will have normal cholesterol
Ebitamide stops cholesterol absorption
Which of the following are atherogenic?
Chylomicrons/chylomicron remnants
LDLs
HDLs
VLDLs
What causes the actual blockage of the artery?
Plaque grows until artery is clogged
Lipid leakage causes clot to form
High HDLs are important because
They remove lipids from the artery
They prevent inflammation and LDL oxidation
Milano HDLs are caused by a genetic mutation and can be used to treat atheroma if infused
What is the supposed role of fibrates? (Since they don't actually work)
Dec TAGs and inflammation
Inc Reversed cholesterol transport, HDL synthesis and LDL particle size
Why was Torcetrapib withdrawn?
People on it did worse
People on it did worse and it increased blood pressiure
It increased blood pressure
HDL type is more important than quantity
