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Hormones involved with body mass
Hormones involved with Linear growth
Where is GH secreted from?
What are the forms of GH?
Hormones homologous to GH?
Where is GHRH released from?
General GH Pathway
When is GH secretion increased?
When is GH secretion downregulated?
Maturation of GH protein
GH Secretion pattern?
GH signals by which pathway?
Effects of GH on target tissue
Effect of GH on the bones
Ghrelin and GH
Somatostatin
IGF interplay with GH
Indirect effects of IGF-1
IGF-1 is similar to what hormone in terms of receptor structure/activation?
IGF release in Aging
IGF-2
When is IGF-2 more predominant?
Describe Insulin, IGF-1, and IGF-2 receptors
Insulin Signaling Path
IGF-1 Signaling pathway
IGF-2 signaling
De-regulation or imbalance of IGF binding proteins leads to what?
Macrosomy
Leprochaunism
Factors that decrease growth
Factors increasing GH
Decreases in HGH
Dwarfism
Gigantism
Acromegaly
How does replacement therapy with GH affect the body?
Signs of GH deficiency?
Clinical manifestations of GH Deficiency
