Pathophysiolgy of Atheroclerosis

Risk Factors for atherosclerosis?

Layers of vessel wall?

Where is cholesterol synthesised?

Main reason for atherosclerosis formation is endothelial dysfunction, how does this happen?

Where does atherosclerosis mainly occur?

What lipoprotein carries cholesterol from the liver to the peripheral tissues?

What does the high density lipoprotein do?

When in excess LDL can go into the intima and become oxydised - what is the effect of this?

What does a macrophage become once it ingests lipid?

Function of cholesterol in the body?

When endothelial cell is damaged what does it release?

What causes the inflammation?

How does the fatty streak formation form?

What do the macrophages do?

Symptoms of atherosclerosis?