Pregnancy and Lactation

Pregunta 1 de 58

1

How many weeks constitute a term pregnancy?

Selecciona una de las siguientes respuestas posibles:

24-30 weeks
30-35 weeks
37-42 weeks
44-46 weeks

Explicación

Pregunta 2 de 58

1

Haz click en los puntos naranjas y selecciona una respuesta correcta para cada uno de ellos

Fill the table below with the appropriate Physiologic/Pharmacokinetic changes

{"33.241_17.9211":[{"id":12658975,"answer":"increase in hepatic metabolism","x":33.241,"y":17.9211},{"id":12658976,"answer":"decrease in hepatic metabolism","x":33.241,"y":17.9211}],"33.5321_39.0739":[{"id":12658977,"answer":"thinning of barrier","x":33.5321,"y":39.0739},{"id":12658978,"answer":"thickening of barrier","x":33.5321,"y":39.0739}],"60.4624_17.8285":[{"id":12658991,"answer":"increase metabolism","x":60.4624,"y":17.8285},{"id":12658992,"answer":"decreased metabolism","x":60.4624,"y":17.8285}],"33.1555_58.7321":[{"id":12658979,"answer":"increased renal blood flow","x":33.1555,"y":58.7321},{"id":12658980,"answer":"decreased renal blood flow","x":33.1555,"y":58.7321}],"61.2157_36.2656":[{"id":12658993,"answer":"increased distribution","x":61.2157,"y":36.2656},{"id":12658994,"answer":"decreased distribution","x":61.2157,"y":36.2656}],"24.675_75.2728":[{"id":12658981,"answer":"increased blood volume","x":24.675,"y":75.2728},{"id":12658982,"answer":"decreased blood volume","x":24.675,"y":75.2728}],"55.7517_57.1438":[{"id":12658995,"answer":"increased GFR","x":55.7517,"y":57.1438},{"id":12658996,"answer":"decreased GFR","x":55.7517,"y":57.1438}],"80.2365_32.9689":[{"id":12659007,"answer":"increased maternal concentration","x":80.2365,"y":32.9689},{"id":12659008,"answer":"decreased maternal concentration","x":80.2365,"y":32.9689}],"42.76_76.1008":[{"id":12658983,"answer":"increased albumin concentration","x":42.76,"y":76.1008},{"id":12658984,"answer":"decreased albumin concentration","x":42.76,"y":76.1008}],"86.6395_18.6527":[{"id":12659005,"answer":"increased concentration","x":86.6395,"y":18.6527},{"id":12659006,"answer":"decreased concentration","x":86.6395,"y":18.6527}],"68.7487_58.2437":[{"id":12658997,"answer":"increased elimination","x":68.7487,"y":58.2437},{"id":12658998,"answer":"decreased elimination","x":68.7487,"y":58.2437}],"54.6244_76.4061":[{"id":12658999,"answer":"increased distribution","x":54.6244,"y":76.4061},{"id":12659000,"answer":"decreased distribution","x":54.6244,"y":76.4061}],"24.1159_90.936":[{"id":12658985,"answer":"decrease motility","x":24.1159,"y":90.936},{"id":12658986,"answer":"increased motility","x":24.1159,"y":90.936}],"32.9632_90.9312":[{"id":12658987,"answer":"increased intestinal blood flow","x":32.9632,"y":90.9312},{"id":12658988,"answer":"decreased intestinal blood flow","x":32.9632,"y":90.9312}],"43.1366_92.5843":[{"id":12658989,"answer":"increased gastric pH","x":43.1366,"y":92.5843},{"id":12658990,"answer":"decreased gastric pH","x":43.1366,"y":92.5843}],"68.5604_76.4061":[{"id":12659001,"answer":"increased protein binding","x":68.5604,"y":76.4061},{"id":12659002,"answer":"decreased protein binding","x":68.5604,"y":76.4061}],"92.8541_43.958":[{"id":12659009,"answer":"increased fetal concentration","x":92.8541,"y":43.958},{"id":12659010,"answer":"decreased fetal concentration","x":92.8541,"y":43.958}],"86.2628_56.87":[{"id":12659011,"answer":"increased concentration","x":86.2628,"y":56.87},{"id":12659012,"answer":"decreased concentration","x":86.2628,"y":56.87}],"55.9427_92.0654":[{"id":12659003,"answer":"increased absorption","x":55.9427,"y":92.0654},{"id":12659004,"answer":"decreased absorption","x":55.9427,"y":92.0654}],"80.6098_75.8499":[{"id":12659013,"answer":"increase concentration","x":80.6098,"y":75.8499},{"id":12659014,"answer":"decrease concentration","x":80.6098,"y":75.8499}],"95.679_76.1313":[{"id":12659015,"answer":"increased free drug concentration","x":95.679,"y":76.1313},{"id":12659016,"answer":"decreased free drug concentration","x":95.679,"y":76.1313}],"86.8278_93.1643":[{"id":12659017,"answer":"increased concentration","x":86.8278,"y":93.1643},{"id":12659018,"answer":"decreased concentration","x":86.8278,"y":93.1643}]}

Explicación

Pregunta 3 de 58

1

Which of the following are true in regards to medication use in pregnancy? (select all that apply)

Selecciona una o más de las siguientes respuestas posibles:

eliminate nonessential drugs
discourage self-medication
minimize exposure to harmful medications
adjust doses for use during pregnancy

Explicación

Pregunta 4 de 58

1

What vaccinations should be administered during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Inactivated influenza vaccine
Tdap ( @ 27-36 weeks)
Hepatitis B
Hepatitis A
Meningitis

Explicación

Pregunta 5 de 58

1

Why are multivitamins used during pregnancy?

Selecciona una de las siguientes respuestas posibles:

fetal bone development
maternal and fetal erythropoiesis
prevent neural tube defect

Explicación

Pregunta 6 de 58

1

Why is calcium used during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

maternal and fetal erythropoiesis
fetal bone development
prevent neural tube defect
prevention of HTN

Explicación

Pregunta 7 de 58

1

Rellena el espacio en blanco para completar el texto.

is used during pregnancy to prevent neural tube defects

Explicación

Pregunta 8 de 58

1

Rellena el espacio en blanco para completar el texto.

Drugs with a molecular weight of less than daltons readily cross the placenta barrier.

Explicación

Pregunta 9 de 58

1

Lipophilic drugs will cross the placental barrier more than hydrophilic drugs

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 10 de 58

1

Which albumin levels are higher, fetal or maternal?

Selecciona una de las siguientes respuestas posibles:

fetal
maternal

Explicación

Pregunta 11 de 58

1

Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 12 de 58

1

Rellena el espacio en blanco para completar el texto.

Only drugs can cross placental membranes

Explicación

Pregunta 13 de 58

1

Rellena el espacio en blanco para completar el texto.

Blood flow to impacts drug transfer to fetus

Explicación

Pregunta 14 de 58

1

What is the drug of choice for the treatment of hyperemesis gravidarum?

Selecciona una de las siguientes respuestas posibles:

ondansetron
pyridoxine
doxylamine
phosphoric acid

Explicación

Pregunta 15 de 58

1

Selecciona la opción correcta del menú desplegable para completar el texto.

The treatment of choice for nausea and vomiting during pregnancy is ( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

Explicación

Pregunta 16 de 58

1

What is the first line or drug of choice for nausea and vomiting during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

pyridoxine
doxylamine
phosphoric acid
metoclopramide

Explicación

Pregunta 17 de 58

1

Selecciona la opción correcta del menú desplegable para completar el texto.

For nausea and vomiting during pregnancy, ( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Explicación

Pregunta 18 de 58

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

Nausea and Vomiting
2nd line therapy is ( metoclopramide, ondansetron, doxylamine, promethazine )
3rd line therapy is ( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

Explicación

Pregunta 19 de 58

1

Rellena los espacios en blanco para completar el texto.

First line line treatment for constipation during pregnancy is incerase and intake

Explicación

Pregunta 20 de 58

1

What drugs should not be used to treat constipation during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

osmotic laxatives
docusate
castor oil
mineral oil
senna
bsicodyl

Explicación

Pregunta 21 de 58

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

GERD/Heartburn

1st line: ( Lifestyle Modifications, antacids or sucralfate, metoclopramide, PPIs )
2nd line: ( antacids or sucralfate, sodium bicarbonate, Ranitidine, PPIs )

Explicación

Pregunta 22 de 58

1

Which of the following treatment can be used to treat Hemorrhoids during a pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Higher fiber intake
increase oral fluid intake
use sitz baths
Topical anesthetics, protectants, and astringents
tylenol

Explicación

Pregunta 23 de 58

1

Bulk forming agents should be utilized to treat diarrhea during pregnancy, what drugs should be avoided?

Selecciona una o más de las siguientes respuestas posibles:

Diphenoxylate/atropine
paregoric
bismuth subsalicylate
psyllium/fiber

Explicación

Pregunta 24 de 58

1

Saline nasal spray/drops are safe to use during pregnancy in the treatment of cough, colds, and allergies

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 25 de 58

1

What is the drug of choice to treat cold , cough, and allergies during pregnancy?

Selecciona una de las siguientes respuestas posibles:

chlorpheniramine
diphenhydramine
loratidine
budesonide

Explicación

Pregunta 26 de 58

1

What drugs are recommended during the 2nd and 3rd trimesters in the treatment of cough, cold, and allergies during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

diphenhydramine
loratidine
cetirizine
beclomethasone

Explicación

Pregunta 27 de 58

1

What nasal steroids are recommended for chronic allergies during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Budesonide (Rhinocort)
Beclomethasone (Beconase AQ)
Advair

Explicación

Pregunta 28 de 58

1

Selecciona la opción correcta del menú desplegable para completar el texto.

( Acetaminophen, opioids, NSAIDs, aspirin ) is the drug of choice for acute pain managment during pregnancy

Explicación

Pregunta 29 de 58

1

What is the drug of choice in the treatment of HTN and severe eclampsia?

Selecciona una de las siguientes respuestas posibles:

labetalol
hydralazine
IV magnesium

Explicación

Pregunta 30 de 58

1

Rellena el espacio en blanco para completar el texto.

IV is used for seizure protection and treatment

Explicación

Pregunta 31 de 58

1

Rellena los espacios en blanco para completar el texto.

Pharmacological treatment for gestational HTN should be started if the systolic BP is greater than OR the diastolic is greater than

Explicación

Pregunta 32 de 58

1

Rellena los espacios en blanco para completar el texto.

Essential/Gestational HTN

1st line (DOC):
2nd line:

Explicación

Pregunta 33 de 58

1

Coagulation Disorders

You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 34 de 58

1

Rellena los espacios en blanco para completar el texto.

Coagulation Disorders

1st line:
2nd line:

Treatment is to be contiuned through pregnancy and weeks after delivery (including breastfeeding)

Explicación

Pregunta 35 de 58

1

Which of the following drugs are contraindicated in the treatment of UTIs during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Cephalexin
Ampicillin
SMX-TMP
Fluoroquinolines
Tetracyclines

Explicación

Pregunta 36 de 58

1

What are the top drug choices in the treatment of UTIs during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Cephalexin
Ampicillin
Nitrofurantoin
Tetracyclines

Explicación

Pregunta 37 de 58

1

What drugs are utilized in the treatment of pyelonephritis?

Selecciona una o más de las siguientes respuestas posibles:

Ceftriaxone
Ampicillin plus gentamicin
Ampicillin-sulbactam
nitrofurantoin
cephalexin

Explicación

Pregunta 38 de 58

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

STI's

Drug of choice syphillis: ( penicillin G, ceftriaxone, amoxicillin, erythromycin )
Drug of choice for gonorrhea: ( ceftriaxone, penicillin G, amoxicillin, erythromycin )
Durg of choice for chlamydia: ( amoxicillin, ceftriaxone, penicillin G, erythromycin ) ; 2nd line: ( erythromycin, amoxicillin, ceftriaxone, penicillin G )

Explicación

Pregunta 39 de 58

1

Acyclovir/valacyclovir is used in the treatment of genital herpes during pregnancy

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 40 de 58

1

Rellena el espacio en blanco para completar el texto.

is the treatment of choice for bacterial vaginosis, and the alternative treatment is clindaymcin

Explicación

Pregunta 41 de 58

1

Rellena los espacios en blanco para completar el texto.

Asthma

is the short acting beta agonist of choice and is the inhaled corticosteriod of choice during preganancy

Explicación

Pregunta 42 de 58

1

During pregnancy, changing agents to minimize risk is NOT recommended for the treatment of epilepsy

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 43 de 58

1

What drugs are the safest to use to treat epilepsy during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

lamotrigine
levetiracetam
valproic acid
carbamazepine

Explicación

Pregunta 44 de 58

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

HIV during pregnancy

New diagnosed: ( HAART, Zidovudine, efavirenz, clindamycin )
( Zidovudine, HAART, efavirenz, clindamycin ) is the mainstay of antiretroviral therapy
Avoid ( efavirenz, Zidovudine, HAART, clindamycin )

Explicación

Pregunta 45 de 58

1

Treatment of schizophrenia, bipolar disorder, depression usually needs to be continued during pregnancy and breastfeeding; high relapse rates if discontinued

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 46 de 58

1

What are the most preferred agents in the treatment of mental health issues in pregnant women?

Selecciona una o más de las siguientes respuestas posibles:

fluoxetine
citalopram
escitalopram
levetiracetam

Explicación

Pregunta 47 de 58

1

Nortriptyline and desipramine are TCAs of choice in the treatment of mental health issues during pregnancy

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 48 de 58

1

Rellena los espacios en blanco para completar el texto.

Treatment of choice for HYPOthryoridism:
Treatment of choice for HYPERthryroidism: or

Explicación

Pregunta 49 de 58

1

Rellena el espacio en blanco para completar el texto.

is the prcoess of stopping contractions

Explicación

Pregunta 50 de 58

1

What drugs are utilized in pre-term labor and tocolysis?

Selecciona una o más de las siguientes respuestas posibles:

IV magnesium
terbutaline
nifedipine
promethazine

Explicación

Pregunta 51 de 58

1

What drugs are needed for cervical ripening?

Cervical ripening: in order to dilate, collagen must loosen and separate; moisture necessary; occurs naturally in women who spontaneously enter labor

Selecciona una o más de las siguientes respuestas posibles:

misoprostol
dinoprostone
oxytocin
methylergonovine

Explicación

Pregunta 52 de 58

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

Labor induction

1st line: ( oxytocin, Methylergonovine, misoprostol, dinoprostone )
2nd line: ( methylergonovine, dinoprostone, misoprostol, Oxytocin )

Explicación

Pregunta 53 de 58

1

Rellena el espacio en blanco para completar el texto.

If mother colonized with Group B Streptococcus:

Explicación

Pregunta 54 de 58

1

Analgesia can prolong the 1st and 2nd stages of labor

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 55 de 58

1

Rellena el espacio en blanco para completar el texto.

analgesia has better profile than parenteral opioids (poor maternal pain relief and less vigorous neonates)

Explicación

Pregunta 56 de 58

1

Rellena los espacios en blanco para completar el texto.

Drug FactorsGeneral Guidelines

Most drugs appear in breast milk to some degree. Most common mechanism of transfer is passive diffusion.

Levels of most drugs in breast milk do not usually exceed 1% to 2% of ingested maternal dosage

If the milk/plasma ratio of drug and active metabolites is less than , it is usually safe to breastfeed

RID: If infant dose is less than % of maternal dose (weight adjusted), it is usually safe to breastfeed

Explicación

Pregunta 57 de 58

1

Depression

Sertraline and paroxetine are most frequently prescribed with few reported adverse effects,

Selecciona uno de los siguientes:

VERDADERO
FALSO

Explicación

Pregunta 58 de 58

1

breast milk is more acidic; weak bases are more likely to stay trapped in breast milk “ion trapping:

Selecciona uno de los siguientes:

VERDADERO
FALSO

	Creado por Mark W. hace alrededor de 8 años

NAPLEX (Endo) Pharmacy Test sobre Pregnancy and Lactation, creado por Mark W. el 14/12/2016.

Pregnancy and Lactation

Pregunta 1 de 58

How many weeks constitute a term pregnancy?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 2 de 58

Haz click en los puntos naranjas y selecciona una respuesta correcta para cada uno de ellos

Fill the table below with the appropriate Physiologic/Pharmacokinetic changes

Explicación

Pregunta 3 de 58

Which of the following are true in regards to medication use in pregnancy? (select all that apply)

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 4 de 58

What vaccinations should be administered during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 5 de 58

Why are multivitamins used during pregnancy?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 6 de 58

Why is calcium used during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 7 de 58

Rellena el espacio en blanco para completar el texto.

is used during pregnancy to prevent neural tube defects

Explicación

Pregunta 8 de 58

Rellena el espacio en blanco para completar el texto.

Drugs with a molecular weight of less than daltons readily cross the placenta barrier.

Explicación

Pregunta 9 de 58

Lipophilic drugs will cross the placental barrier more than hydrophilic drugs

Selecciona uno de los siguientes:

Explicación

Pregunta 10 de 58

Which albumin levels are higher, fetal or maternal?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 11 de 58

Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier

Selecciona uno de los siguientes:

Explicación

Pregunta 12 de 58

Rellena el espacio en blanco para completar el texto.

Only drugs can cross placental membranes

Explicación

Pregunta 13 de 58

Rellena el espacio en blanco para completar el texto.

Blood flow to impacts drug transfer to fetus

Explicación

Pregunta 14 de 58

What is the drug of choice for the treatment of hyperemesis gravidarum?

Selecciona una de las siguientes respuestas posibles:

Explicación

Pregunta 15 de 58

Selecciona la opción correcta del menú desplegable para completar el texto.

The treatment of choice for nausea and vomiting during pregnancy is nonpharmacological treatment pyridoximine and doxylamine emetrol( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

Explicación

Pregunta 16 de 58

What is the first line or drug of choice for nausea and vomiting during pregnancy?

Selecciona una o más de las siguientes respuestas posibles:

Explicación

Pregunta 17 de 58

Selecciona la opción correcta del menú desplegable para completar el texto.

For nausea and vomiting during pregnancy, phosphoric acid metoclopramide dopamine diclegis( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Explicación

Pregunta 18 de 58

Selecciona la opción correcta de los menús desplegables para completar el texto.

Nausea and Vomiting 2nd line therapy is metoclopramide ondansetron doxylamine promethazine( metoclopramide, ondansetron, doxylamine, promethazine ) 3rd line therapy is dopamine antagonist dicelgis ondansetron methylprednisone( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

Explicación

Pregunta 19 de 58

Rellena los espacios en blanco para completar el texto.

First line line treatment for constipation during pregnancy is incerase and intake

Explicación

Pregunta 20 de 58

What drugs should not be used to treat constipation during pregnancy?

The treatment of choice for nausea and vomiting during pregnancy is ( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

For nausea and vomiting during pregnancy, ( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Nausea and Vomiting
2nd line therapy is ( metoclopramide, ondansetron, doxylamine, promethazine )
3rd line therapy is ( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

GERD/Heartburn

1st line: ( Lifestyle Modifications, antacids or sucralfate, metoclopramide, PPIs )
2nd line: ( antacids or sucralfate, sodium bicarbonate, Ranitidine, PPIs )

( Acetaminophen, opioids, NSAIDs, aspirin ) is the drug of choice for acute pain managment during pregnancy

Essential/Gestational HTN

1st line (DOC):
2nd line:

Coagulation Disorders

You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies

Coagulation Disorders

1st line:
2nd line:

Treatment is to be contiuned through pregnancy and weeks after delivery (including breastfeeding)