Biomaterials - Introduction (wk. 1)

Fingerjoint

Breast Implant

Heart Valve

Hip Joint

Artificial Heart

Intraocular Lens
(IOL)

Applications of Biomaterials:
Sutures
Name 5 advantages

Intraocular Lens - name
a) materials
b) 3 properties

Name as many medical device examples as you can.
There are 12 on the slides

Which are Biomaterials? why?
a) contact lens
b) splinter
c) vascular graft
d) clutches

Biomaterial

Biomaterials Science

biocompatibility

Reasoning Biocompatibility

Biocompatibility responses:
1) temporal
2) other

Bioimplants trigger....

biocompatibility testing

biocompatibility testing agencies

biocompatibility testing steps

New testing required for
a) new devices
b) new materials
c) both new devices and materials

amount of testing depends on

Types of biomaterials

Cobalt-chromium alloys:
Co-Cr
Applications (3)

Au, Pt
Gold & Platinum

Silver-tin-copper alloys
Ag-Sn-Cu

Stainless steel

Titanium alloys

Ceramics:
aluminum oxide
Al2O3

Ceramics:
Bioactive glasses

Ceramics:
Calcium Phosphates

Natural Polymers

Collagen

Fibrin

Chitosan

Synthetic polymers

Natural vs. Synthetic Polymers

Which class(es) of biomaterials for an artificial tendon? why?

[hint: a tissue that must sustain substantial deformation at low forces and return rapidly to its original dimensions upon release of stress]

a) metals
b) ceramics
c) polymers

Important properties of biomaterials:
The selection of biomaterials for a given application is determined by:
(3)

Biodegradable

Medical Applications of Biodegradable Poolymers

What are the 4 layers of a biomaterial interfacing with a biological system?

Importance: Surface properties

chemical vs physical characteristics (surface property)

Would a hydrophobic or hydrophilic polymer be more appropriate for a contact lens application? Why?

Would a melting temperature of the polymer above or below 37 degrees be better? why?

importance: Bulk properties

mechanical, physical, chemical properties
(bulk property)

spectroscopy

chromatography