Haemolytic Anaemia

Life span of RBCs:

Reasons for reduced red cell survival in the circulation:

Marrow responds with increased production of RBCs, resulting in:

Main tests for haemolysis:

Other tests for haemolysis:

Inherited haemolytic anaemia categories:

Glucose-6-phosphate dehydrogenase deficiency:
Pathophysiology:
Clinical effects:
Blood film results:

Spleen the filter:
Channel types:

Thalassaemia:
Pathophysiology of haemolysis:

Autoimmune haemolytic anaemia:
Pathophysiology:
Test:
Treatment options:

Hereditary spherocytosis:
Pathophysiology:
Long term consequences:
Treatment:

Intravascular haemolysis:
Causes:

Thrombotic thrombocytopenic purpura (TTP):
Features:
Pathophysiology:
Mortality:
Treatment:

Haemolytic uraemic syndrome (HUS):
Main age group affected:
Causative agent:
Pathophysiology:
Consequences:
Treatment:

HELLP syndrome:
Features:
Pathophysiology:
Consequences:

Heart valve-mechanical haemolysis:
Causes:
Effect on urine:

Paroxysmal nocturnal haemoglobinuria:
Pathophysiology:
Patients suffer from:
Treatment: