Mer Scott
Test por , creado hace más de 1 año

• Outline the sequence of events that results in the secretion of growth hormone. • Describe the metabolic effects of growth hormone on each type of target cell. • Describe the effects of growth hormone on human growth (during the growth years and after skeletal fusion) • Explain what occurs when there is too much or too little growth hormone secreted during childhood.

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Mer Scott
Creado por Mer Scott hace alrededor de 7 años
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L35: Growth Hormone

L35: Growth Hormone

Pregunta 1 de 18

1

What percent of cells in the anterior pituitary are somatotrophs, which produce growth hormone?

Selecciona una de las siguientes respuestas posibles:

  • 50%

  • 20%

  • 70%

  • 95%

Explicación

Pregunta 2 de 18

1

Choose the incorrect statements.

Selecciona una o más de las siguientes respuestas posibles:

  • 20% of the cells in the anterior pituitary gland are mammotrophs.

  • 20% of the cells in the anterior pituitary gland are corticotrophs.

  • 50% of the cells in the anterior pituitary gland are thyrotrophs.

  • 5% of the cells in the anterior pituitary gland are somatotrophs.

Explicación

Pregunta 3 de 18

1

SS stands for:

Selecciona una de las siguientes respuestas posibles:

  • Somatostatin

  • Somastatin

  • Somatostatic

Explicación

Pregunta 4 de 18

1

Somatotrophin is another name for growth hormone.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 5 de 18

1

Growth hormone has been able to be produced in vitro since 1979.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 6 de 18

1

Selecciona la opción correcta de los menús desplegables para completar el texto.

Growth hormone is a ( peptide, protein ) hormone. It is ( small, long ) (191 amino acids). The secretion of GH is ( pulsatile, continuous ) and has a ( daily, hourly ) rhythm which differs between males and females.

Explicación

Pregunta 7 de 18

1

Growth hormone's half life in the blood is 20-25 minutes.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 8 de 18

1

Growth hormone is an exception for hormones because it travels in the .

Arrastra y suelta para completar el texto.

    peptide
    protein
    blood bound to a protein carrier
    without a protein carrier

Explicación

Pregunta 9 de 18

1

Growth hormone releasing hormone neurons (GHRH neurons) in the are excited and release into the anterior pituitary gland where it stimulates to release growth hormone (GH). GH is released into the bloodstream where it stimulates production in the .
IGF-1 feeds back to the hypothalamus where it more release of GHRH and stimulates to inhibit release of by the anterior pituitary gland.

Arrastra y suelta para completar el texto.

    hypothalamus
    GHRH
    somatotrophs
    insulin-like growth factor (IGF-1)
    liver
    inhibits
    somatostatin (SS)
    GH

Explicación

Pregunta 10 de 18

1

Choose the correct statements.

Selecciona una o más de las siguientes respuestas posibles:

  • Growth hormone release peaks during the night and settles down during the day, but is constantly spiking.

  • The growth hormone secretion peak is less pronounced for males.

  • Release of GH increases with age until it peaks at puberty.

  • The puberty peak of GH release occurs earlier for females than males.

Explicación

Pregunta 11 de 18

1

Growth hormone is essential for until around age 8, rapid growth of in two separate periods, and growth of around puberty.

Arrastra y suelta para completar el texto.

    brain development
    height
    reproductive organs

Explicación

Pregunta 12 de 18

1

Growth hormone receptor is a single molecule found in the membrane that does not require activation.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 13 de 18

1

Which of these is not a long term effect of growth hormone?

Selecciona una de las siguientes respuestas posibles:

  • Stimulation of bone and muscle growth

  • Stimulation of mitogenesis (cell division) via IGF-1

  • Stimulation of protein synthesis (in liver)

Explicación

Pregunta 14 de 18

1

Stimulation of mitogenesis via IGF-1 is a direct effect of growth hormone.
Stimulation of protein synthesis in muscle by is an indirect effect of growth hormone.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 15 de 18

1

Short term effects of growth hormone are always direct.

Selecciona uno de los siguientes:

  • VERDADERO
  • FALSO

Explicación

Pregunta 16 de 18

1

Choose the correct effects of GH on metabolism(short term effects).

Selecciona una o más de las siguientes respuestas posibles:

  • Increase in blood glucose by stimulating glucose synthesis (in
    liver)

  • Increase in blood glucose by stimulating cellular uptake of glucose

  • Decrease in triglyceride breakdown in adipose tissue

  • Free fatty acid mobilisation in adipose tissue

Explicación

Pregunta 17 de 18

1

Other hormones important for are thyroid hormones, insulin, cortisol, and estrogen/testosterone.
Thyroid hormone the basal metabolic rate and is essential for development.
Insulin and increase metabolism.
Estrogen/testosterone are essential during .

Arrastra y suelta para completar el texto.

    growth
    increases
    nervous system
    glucose
    puberty
    cortisol

Explicación

Pregunta 18 de 18

1

Endocrine disorders can be due to too little GH () or too much GH ().
An of GH can cause gigantism or acromegaly. Acromegaly is an excess of GH in which leads to thickening of , and of soft tissues in the hands, feet and face. A can cause dwarfism.
Endocrine disorders can also result from an issue in the GH . Hyposensitive receptors to GH and the effects are similar to hyposecretion. Hypersensitive receptors to GH and have similar effects to hypersecretion.

Arrastra y suelta para completar el texto.

    hyposecretion
    hypersecretion
    excess
    adulthood
    childhood
    bones
    muscles
    deficiency
    receptors
    give little or no response
    overreact

Explicación

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