A&P: PULMONOLOGY

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The lungs are attached to the thoracic cavity at the and the . The parietal and visceral pleura meet at the to create a sheath for the mainstream bronchi, the pulmonary vessels, and the nerves. The apex rises slightly above the level of the clavicle. The base rests on the diaphragm.

The space between the lungs is the . It contains the heart, the great vessels, the esophagus, and the lymphatics.

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Pregunta 5 de 21

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Inspiration is an active process. The ( medulla, cervical plexus, phrenic nerve ) sends and impulse down the ( cervical plexus, medulla, phrenic nerve ) to the ( phrenic nerve, medulla, cervical plexus ), stimulating the diaphragm to contract. Because the ( phrenic nerve, medulla, cervical plexus ) receives impulses through the ( cervical plexus, medulla, phrenic nerve ) at the level of the fourth cervical nerve, spinal injury between the level of the 3rd and 5th cervical nerves will affect ventilatory function.

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Pregunta 6 de 21

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In expiration, the diaphragm relaxes and resumes its dome shape, pushing upward on the lungs. The lungs, chest wall, and abdomen recoil elastically, compressing the lungs and ejecting the air, similar to a balloon collapsing. The muscles help pull the ribs downward.

During forced expiration, coughing, physical exertion, or airway obstruction, expiration becomes and active process and requires recruitment of accessory muscles. Accessory muscles include the muscles and .

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Pregunta 7 de 21

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The upper airways consist of the trachea, nasal and oral cavities, pharynx, and larynx. No gas exchange occurs in the conducting (upper) airways.

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Pregunta 8 de 21

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The trachea is a hollow tube about in long and one inch in diameter. It starts at the cricoid cartilage and extends to the carina, where it bifurcates into the mainstem bronchi.

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Pregunta 9 de 21

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The alveoli comprises primarily type I and type II alveolar epithelial cells. Type I make up the majority of the alveolar surface which is where gas exchange takes places. Inhaled toxins easily injure Type I cells. Type II cells are small and numerous and move in when Type I are injured, eventually transforming into Type I cells. Type II cells produces, secrete and store pulmonary surfacant.

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alveolar sac

Type I cell

Type II cell

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Pia matter

spinal cord

subarachnoid space

dura mater

epidural space

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Pregunta 11 de 21

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Bronchial circulation does not participate in gas exchange. Once blood circulates through and delivers its oxygen load, most of it is returned to the right side of the heart. A small amount travels via the pulmonary veins to the LA where it mixes with the fully oxygenated blood. This anatomical shunt results in an oxygen saturation of 96-99%. For this reason, a person breathing room air will never register an arterial oxygen saturation of 100%.

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When the muscles of inspiration contract to create a larger space within the chest, the ( parietal pleura, visceral pleura, intrapleural space ) moves outward, increasing negative pressure in the ( intrapleural space, visceral pleura, parietal pleura ). Intrapleural pressure drops from a resting pressure of -4 cm H2O to -10 cm H2O. This negative pressure creates pull on the ( visceral pleura, parietal pleura, intrapleural space ) and the lungs expand. At this point, pressure inside the lungs is less than atmospheric pressure, so air moves into the lung.

During expiration, the muscles of the thorax relax, compressing the lungs and increasing intrapulmonary pressure. When intrapulmonary pressure becomes greater than atmospheric pressure, air moves out of the lungs.

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Pregunta 13 de 21

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Increased PCO2 in blood and CSF

Stimulates chemorecep in medulla

Increases RR

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Pregunta 14 de 21

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Label peripheral chemoreceptors:

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carotid sinus nerve

Left external carotid artery

carotid sinus receptors

Left internal carotid receptor

Left Common Carotid artery

Right Common Carotid artery

vagus nerve

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Pregunta 15 de 21

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During ventilation, central and peripheral chemoreceptors respond to changes in blood and other fluid chemistry. Additional sensors include juxtacapillary receptors (J-receptors), and receptors attuned to stretch and irritants.

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residual volume

tidal volume

inspiratory reserve

expiratory reserve

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Pregunta 17 de 21

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Any time alveoli are dysfunctional, gas exchange is impaired. When alveoli are not ventilated but blood is still perfusing the area, occurs.

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Alveoli may be ventilated, but have no corresponding blood flow to pick up oxygen, as in the case of pulmonary emboli. This is also known as alveolar dead space, or a ( high V/Q shunt, low V/Q shunt ).

Occurs when adequate blood flow surrounds underventilated alveoli. The clinical effect of ( low V/Q, high V/Q shunt ) is similar to shunting, and may result from similar pathology.

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Pregunta 19 de 21

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2,3 diphosphoglycerate (2,3 DPG) is an organic substance in red blood cells that affects the affinity of hemoglobin for oxygen. A dramatic increase in tissue oxygen requirements spurs an acute increase in 2,3 DPG production.

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Pregunta 20 de 21

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Carbon dioxide levels in the capillaries are lower than in the cells, allowing CO2 to move into the blood. Some carbon dioxide is carried dissolved in the plasma (indicated in the blood gas as PaCO2), some is bound to proteins including hemoglobin, but the majority is carried as HCO3 , the result of the formation and dissociation of carbonic acid.

As blood circulates back to the lungs, these compounds release the carbon dioxide, which then diffuses across the alveolar-capillary membrane into the alveoli in preparation for expiration.

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HCO3-

carbonic anhydrase

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Pregunta 21 de 21

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may be due to decreased blood pH, increased carbon dioxide (PaCO2), elevated temperature, and/or increased 2,3 DPG. When shifted right, oxygen is more easily detached from hemoglobin, enhancing delivery to tissues, even at lower oxygen saturation levels.

may be due to increased blood pH, decreased carbon dioxide, decreased temperature, and/or decreased 2,3 DPG. When the curve is shifted left, the bond between oxygen and hemoglobin is stronger and it is more difficult for hemoglobin to release oxygen to the tissue. Even if oxygen saturation is higher, tissue hypoxia may result.

	Creado por Narda Carrion-Hernandez hace más de 7 años

Fundamentals Test sobre A&P: PULMONOLOGY, creado por Narda Carrion-Hernandez el 11/07/2017.

A&P: PULMONOLOGY

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Pregunta 7 de 21

The upper airways consist of the trachea, nasal and oral cavities, pharynx, and larynx. No gas exchange occurs in the conducting (upper) airways.

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Explicación

Pregunta 8 de 21

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The trachea is a hollow tube about in long and one inch in diameter. It starts at the cricoid cartilage and extends to the carina, where it bifurcates into the mainstem bronchi.

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Pregunta 9 de 21

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Pregunta 10 de 21

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Pregunta 13 de 21

Label ventilation cycle:

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Pregunta 14 de 21

Label peripheral chemoreceptors:

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Explicación

Pregunta 15 de 21

During ventilation, central and peripheral chemoreceptors respond to changes in blood and other fluid chemistry. Additional sensors include juxtacapillary receptors (J-receptors), and receptors attuned to stretch and irritants.

Selecciona uno de los siguientes:

Explicación

Pregunta 16 de 21

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Pregunta 17 de 21

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Any time alveoli are dysfunctional, gas exchange is impaired. When alveoli are not ventilated but blood is still perfusing the area, occurs.

Explicación

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Pregunta 19 de 21

2,3 diphosphoglycerate (2,3 DPG) is an organic substance in red blood cells that affects the affinity of hemoglobin for oxygen. A dramatic increase in tissue oxygen requirements spurs an acute increase in 2,3 DPG production.

Selecciona uno de los siguientes:

Explicación

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