Circulatory Systems VII

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Flashcards on Circulatory Systems VII, created by J yadonknow on 25/04/2018.
J yadonknow
Flashcards by J yadonknow, updated more than 1 year ago
J yadonknow
Created by J yadonknow over 6 years ago
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Question Answer
What is vasomotion? spontaneous oscillation in tone of blood vessel walls, independent of heart beat, innervation or respiration
Microcirculation capillary BV Small arterioles - smooth muscle w/ symp. innervation. Term. arterioles - Controlled by local metabolites Pre-capillary sphincters
Diagram of capillary network (6) terminal arteriole Pre-capillary spincters metarterioles true capillaries thoroughfare channels postcapillary venule
What is a thoroughfare channel? Direct connection of metarteriole to venule (skips capillary)
Function of pericytes Stabilise newly formed capillary Maintain BBB Regulate cerebral BF at level of individual capillary
What does BBB control? Movement of ions/solutes btw. continuous capillaries and choroid plexus
How do they do this? Have TJ which prevent movement of hydrophilic solutes Specialised transporters which allow controlled movement across capillary wall
Tissues that capillary types found in Cont. - muscle Fen. - Endocrine gland Discontinous - bone marrow
Why can CO2/O2 cross continuous cap? As they're lipophilic
Show a diagram of CO2 X in capillaries Bicarbonate formation accounts for most of the difference btw. total[CO2] and dissolved [CO2].
What are the four starling forces? cHSP/iHSP BCOP/ICOP
How is bCOP formed? Colloid proteins, especially albumin, insoluble and too large to cross endothelium Accounts for reabsorption of H2O
What happens when edema? Low protein content BCOP low Excess fluid drained from cap. Leads to excess build-up in tissues
Describe fluid movement at arterial side of capillary cHSP>> iHSF cHSP>>BCOP Net filtration as fluid forced against walls of capillary
Why cHSP>> iHSF? Lymphatic vessels constantly drained into subclavian veins of the neck Low protein content so low HSP
What happens at venous side of capillary? BCOP>cHSP Water drawn in
Which is larger, net. filtration or net absorption? Net absorption, as cHSP > BCOP so inevitable that more fluid will be forced out than drawn back in
Transcytosis Exocytosis of large lipid insoluble compounds into a lipid vesicle by endothelial cells
Bulk Flow Small lipid-insoluble solutes in H2O Direction depends on net filtration pressure derived from 4 Starling Forces
What transport do capillaries of BBB use? Transcellular Transport
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