17928021
Description
Flashcards by Michelle Zanette, updated more than 1 year ago
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Created by Michelle Zanette
over 5 years ago
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| Question | Answer |
| Samuel Hahneman | - diseases viewed as an invader fought with whatever method in favour at the time - tx Cinchoria on his body & "drug picture" mirrored symptoms of Malaria - "proving" |
| Cinchoria | Peruvian bark with anti-malaria properties - gives the drug: Quinidine |
| Materia Medica | written by Dr. Cullen - all drug pictures - homeopathy |
| homeopathy | substance that causes symptoms of disease in healthy ppl would cure similar symptoms in sick people |
| main principles of homeopathy | like cures like minimal dose single remedy |
| SARCODES | microbial culture (homeopathy) |
| NOSODES | bodily samples (homeopathy) |
| extraction (homeostasis) | mother tincture = 1:3, material:alcohol/water solids: titration w lactose - titivate given or powder, or a MT |
| Chagra | beside the maloca, a garden where food and medical plants are cultivated - surrounded by primary jungle |
| Paiki | fam Rubiaceae - solidarity tree - carnivorous ants mutualism "the pharmacy" |
| Catarijano | basket |
| Yew | taxus bachata - planted on holy sites - tree of eternal youth |
| Coca | aka Mambe - toast + pulverise - combine w Yarumo - makes it a "free base" - fat soluble due to the alkali |
| Yarumo | - burned to dry - added to Coca to make Mambe |
| Tabacco | - add veg salt (fruit of Palma real turned to ash and boiled) - to make Ambil (black syrup) - protect against negative energies |
| Ambil | defense gifts "pay" balance energy invite to dance test for elders powers, or an energy |
| Yaje | hallucinogenic communicate with gods + for rituals "journey" to look for cure alkaloids attack neurotransmitters (DMT, serotonin) illegal in UK |
| Brugmansia sp | hallucinogen from solanaceae sacred, magical, healing powers journeys + initiate shaman "Flor Del Inca" "Trumpet of Angels" template for useful medicines |
| Plant Solanaceae | atropine (racemic, (-)-hycoscamine) scopolamine ((-)-hycosine) "truth drug" |
| Belladonna | Atropine Hycosine |
| Achiote | (seed) body paint + insect repellant (fruit) tx skin infection + protect annatto food colourant Bixa sp. dyes related to carotenoids + vit A |
| Paullinia Yoco | Fungi caffeine + theobromine similar to tryptamine Gurana drink - prepared from the fruit |
| Plant Sap | hallucinogenic properties tx infections, cancer compare to large acid - cytotoxic - aromatic - taspine |
| Bejucos de agua | water vines anti-microbial tx diarrhea quercetin aromatic compounds |
| fungi | tx mouth infections, antibiotic effects cinnabarin alkaloid responsible for activity use: red, young dont use: black (toxic) |
| Pymoporus sangurieus | fungi act on HIV |
| chuchuguasa | indigenous tx arthritis west tx cancer east side of tree @ 5 am Maytasine = cytotoxic compound disrupts cell division |
| Sacho Ajo | vine keep (-) energy away + witch craft saebedor use tobacco for protection during collection - garlic smell lapachone type compounds allicin: anti-bacterial/viral |
| garlic | (allium satvium) amazon: (-) energies allicin: anti-bacterial/viral ajoene: anti-thrombic/fungal cis(7)ajoene: anti-tumor |
| Pilocarpus Jaborandi | eye drops mimic Ach, parasymmp tx: glaucoma traditionally: tx power salvation + sweating activity |
| Amazon Healing Process | Diagnosis Location Collection Preparation Conjuration |
| Conjuration | Labiatae: cleanse + remove "bad air" Sentilla: bathe pt bring pt back to balance with community w a dance |
| Kodurio | tree bark, liquid tx: skin + ear infection + sunburn ellagic acid derivative like taspine |
| Rubicaceace fam | common wound healing indoid glucosides (sugar units) root bark used more |
| Labiatae | remove negative energies during conjuration cleanse + remove "bad air" |
| Sentilla | attract positive energies in conjuration used to bathe pt |
| Bathysa cuspidata | Rubicaecae fam paeonol: active constituent for womb healing (phenolic compound) |
| Nettle | Urera sp aka Ortiga use for hair + pain tx: bruises + diuretic active constituent: histamine |
| Barbasco | poisonous chemical compound roots used for fishing as insecticide constituent: rotenone |
| Incense | saebador in mambeadero - purify maloca collected from tree bark - resin |
| frankincense | boswella acid anti-microbial |
| Renin | Injury creates resin seals and hardens - prevent tree infection (defence) lipid soluble anti-fungal activity - iguana triterpene (similar to fusidic acid) freeze, open, collet larvae b4 transport |
| Flower Remedies | spring water + sunlight = make fluids tx: emotional stress Bach Rescue Remedy |
| Aromatherapy | topical: dilute w veg oil internal: medical supervision externally: hot water + towel, or on pillow citrus als: increase sensitivity to sunlight seizures in epileptics (sage, rosemary, fennel, hyssop) |
| Gattefossé | aromatherapy tx: burns + infected wounds |
| Traditional Chinese Medicine - practices | CHM acupuncture acupressure meditation Tai Chi |
| Yin | cold, dark |
| Yang | heat, light |
| Yinyang | balence |
| Qi | Energy |
| Indian Ayuvedic Medicine | nutrition yoga mediation oil massage herbal teas for physical/emotional harmony |
| vata/pitta/kapha | lean/muscular/stocky |
| Ayuvedic | veda: self-knowledge Ayu: of life |
| Traditional Herbal Regulatory Scheme | HM accessed info ab safe use efficacy based on traditional use evidence of efficacy? = full product lisence |
| MHRA | Regulatory Agency for Herbal Medicines |
| maceration | soften using fluid |
| infusion | pour hot water on top |
| decoction | boil herbal material |
| percolation | filtering |
| Aristolochia | prohibited HM! kidney failure + cancer |
| Kava Kava | restricted HM! external use only |
| Senecio | Prohibited HM! |
| Ginseng | Prohibited HM! Foetal skeletal malformation |
| Anecdotal evidence | not scientific |
| preliminary | too little research for definite conclusion |
| inconclusive | inconsistent/contraindicative |
| conclusive | consistant in large group meta analysis (only a few HPs) |
| Ginkgo biloba | claim: increase cerebral + peripheral blood PRELIM: prevent/reduce memory deterioration GI problems, allergic skin rxn w aspirin = risk of excessive bleeding |
| Echinacea Purpurea | SCI EVI: IS, anti-viral/inflam/microbial, wound healing PRELIM: improve symptoms shorten duration INCONC: reduce frequency of other infections |
| Hypericum Perforatium (St. Johns Wort) | dried flowering plants - "natural Prozac" SCI: anti-dep/viral/bacterial PRELIM: reduce SE, increase efficacy mod/mild depression compared to Prozac induce metabolic enzymes = reduce therapeutic effect reinforce Prozac (lethargy, anxiety, nausea) |
| Hit identification | NP screened for activity against selective target "Hits" = bioactive compounds |
| High throughput screening (HTS_ | assays automated robotics biochem target - screen - identify hits - inspiration for leads |
| semi-synthesis | extract intermediate precursor, convert to final product bc isolating NPs can be costly, sustainable and ecological challenge intermediate could be easier to extract |
| total synthesis | synthesize given NP |
| "Hit-to-Lead" optimization | hits with desired effect are modified to optimize potency + reduce toxicity |
| pharmodynamics | drug does to body |
| pharmokinetics | body does to drug |
| Natural Product Discovery | extraction - organic solvents exploit solubilities in NPs complex matrices, TLC Separation - automated, precipitation, crystallization, chromatography Structure ID - optimization - production |
| Taxanes | anti-cancer yew, ex. paclitaxel, pocetaxel bind + inhibit tululin = microtubule network stops moving inhibit cell division @ disassembly |
| Vinca Alkaloids | anti-cancer anti-diabetic ex. periwinkle tubular, inhibit polermisation and ASSEMBLY |
| Etoposide | May apple plant purgative to burn off skin tumors |
| Irenotecan, Topotecan | anti-cancer TCM ling + colon |
| analgesics/anti-tussive | morphine oppium poppy |
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