20121832
Description
Flashcards by Sam Adeyiga, updated more than 1 year ago
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Created by Sam Adeyiga
about 5 years ago
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| Question | Answer |
| Atorvastatin Brand | Lipitor |
| Atorvastatin Dosage form | Tablets 10, 20, 40, 80 mg QD |
| Atorvastatin AE | Myopathy, dyspepsia Constipation, diarrhea |
| Atorvastatin Counseling | Avoid overexposure to sunlight due to possibility of photosensitivity. Use sunscreen and appropriate cloth till level of sensitivity is determined |
| Atorvastatin Monitor | LFT Lipid Panel |
| Atorvastatin Prego category | Category X |
| Ezetimibe Brand | Zetia |
| Ezetimibe Dosage Form | Tablet 10 mg (* only available Conc) QD |
| Ezetimibe AE | Myopathy/rhabdomyolysis Myalgia, Increased CPK, Hepatitis, Increased liver transaminases Arthralgia, urticaria, thrombocytopenica |
| Atorvastatin DDI | 1. May increase DIGOXIN 2. Lipitor level may be REDUCED in the body when use w/ gemfibozil, GRAPEFRUIT, clarithromycin, antifungal, HIV drugs and CYCLOSPORINE |
| Ezetimibe DDI | 1. Zetia level in the body will increase w/ gemfibrozil and fenofibrate use 2. Zetia level will DECREASE in the body with the use of Cholestryamine |
| Ezetimibe counseling | 1. Take 2 hrs before or 4 hrs after taking Cholestryramine |
| Ezetimibe monitoring | Lipid panel |
| Ezetimibe prego category | category C |
| Fenofibrate Brand | Tricor Lipofen |
| Fenofibrate Dosage form | Tablets: 54 mg and 160 mg Capsule: 134mg and 200 mg (red capsule) *Recommended: 134 - 200 mg PO QD |
| Fenofibrate DDI | 1. Lipofen may increase effect of WARFARIN 2. Cholestyramine may decrease the effect of absorption of lipofen 3. avoid use w/ STATINs bc of an increase risk of rhabdomyolysis |
| Fenofibrate AE | 1. Muscle pain, rash, tenderness or weakness 2. Pain: resp disorder, abdominal pain, back pain and headache |
| Fenofibrate counseling | 1. Take w/ meal to increase absorption |
| Fenofibrate monitoring | LFT RFT Lipid panel |
| Fenofibrate prego category | Avoid in pregnancy and lactation/nursing |
| Gemfibrozil Brand | Lopid |
| Gemfibrozil Dosage Form | 1. Tablet: 600 mg (only) * RD 737 and Lopid written on it 2. 600 mg PO BID (30 mins b4 a.m. and p.m. meal) |
| Gemfibrozil DDI | 1. May enhance anticoagulant meds (Warfarin, DOACs, UFH and LMWH) 2. Administration w/ LOVASTATIN may cause severe myopathy or rhabdomyolysis |
| Gemfibrozil AE | 1. Dyspepsia, abdominal pain 2. diarrhea, nausea, fatigue |
| Gemfibrozil counseling | 1. May cause dizziness 2. May cause blurred vision |
| Gemfibrozil monitor | Lipid panel LFT FBG |
| Gemfibrozil prego category | Category B |
| Fenofibrate (nanocrystallized) Brand | Tricor |
| Fenofibrate (nanocrystallized) Dosage forms | Tablets: 48 mg (peach color and has F1 written on it); 145 mg (white color and has F0 written on it) *Recommended dosage: 145 mg PO QD w/ meal ** Renal impairment: Initial dose = 48 mg PO QD w/ meal |
| Fenofibrate (nanocrystallized) monitor | LFT RFT Lipid panel |
| Fenofibrate (nanocrystallized) prego category | Category C |
| Lovastatin Brand | Mevacor |
| Lovastatin Dosage Form | Tablets: 10 mg (peach color, MSD 730) 20 mg (purple color, MSD 731) 40 mg (green color, MSD 732) * Recommended dosage: 20 mg PO QD w/ evening meal ** Increase dosage @ 4 wk interval for max response. |
| Lovastatin DDI | 1. Avoid coadministrtaion w/ GEMFIBROZIL due to severe myopathy and rhabdomyolysis. 2. Avoid GRAPEFRUIT juice, it increases mevacor level in the body |
| Lovastatin AE | 1. Myalgia, blurred vision 2. dyspepsia, abdominal cramps, constipation, diarrhea, heartburn, nausea, headache, rash/pruritus, flatus |
| Lovastatin counseling | 1. take med w/ meal 2. Avoid exposure to sunlight. |
| Lovastatin monitor | LFT Lipid panel |
| Lovastatin prego category | Category X |
| Niacin (ER) Brand | Niaspan |
| Niacin (ER) Dosage Form | Tablets ER: 500 mg (500 written on it) 750 mg (750 written on it) 1000 mg (1000 written on it) * Start w/ 500 mg at bedtime for 4 wks |
| Niacin (ER) DDI | 1. Rare cases of rhabdomyolysis has occurred in Niacin + Statins dual therapy 2. Cholestyramine may decrease the effect of absorption of niacin, give a minimum of 4 hrs b4 or after administration of Cholestyramine |
| Niacin (ER) AE | 1. Flushing 2. Pruritus (itching) and rash. |
| Niacin (ER) counseling | 1. take at bedtime w/ a low fat snack 2. Do not take on empty stomach 3. Flushing subsides after a few weeks 4. ASA or NSAIDs taken shortly b4 bedtime may reduce flushing 5. Avoid taking OTC supplement w/ Niacin w/o 1st checking w/ your prescriber 6. Swallow tablet whole and do not break, crush or chew |
| Omega-3-Acid Brand | Lovaza |
| Omega-3-Acid Dosage Form | Liquid-Filled Gel Capsule: 1000 mg capsule contains 900 mg ethyl esters of Omega-3 fatty acid (including ~ 465 mg EPA and 375 mg DHA) * Takes 4 capsules (4000 mg) either QD or divided two doses w/ meal |
| Omega-3-Acid DDI | May increase bleeding time w/ anticoagulants (Warfarin, DOACs, UFH, LMWH) |
| Omega-3-Acid AE | 1. Angina 2. Back pain 3. Dyspepsia 4. belching 5. rash 6. Miscellaneous infection 7. Taste perversion 8. Flu-like snxs |
| Omega-3-Acid counseling | 1. Take w/ food 2. Store away from sunlight and children |
| Omega-3-Acid monitor | Lipid panel |
| Omega-3-Acid prego category | Category C |
| Pravastatin Brand | Pravachol |
| Pravastatin Dosage Form | Tablets 10 mg (peach color, 10 on the tab) 20 mg (yellow color, 20 on the tab) 40 mg (green color, 40 on the tab) 80 mg (orange color, 80 on the tab) * Start w/ 10-20 mg PO QD HS |
| Pravastatin DDI | 1. Coadministration of pravachol w/ Cholestyramines or colestipol = decrease of pravachol. Give pravachol 1 hr b4 or 4 hrs after Cholestyramines or colestipol. 2. Not affected by GRAPEFRUIT juice |
| Pravachol AE | 1. Muscle pain 2. dyspepsia, headache, rash, Flu |
| Pravastatin counseling | 1. Do not become pregnant during therapy 2. Avoid sunlight 3. Limit alcohol intake |
| Pravastatin monitor | LFT Lipid panel |
| Pravastatin prego category | Category X |
| Rosuvastatin Brand | Crestor |
| Rosuvastatin Dosage Form | Tablets: 5 mg (orange color) 10, 20, 40 mg (peach color) * Maintenance dose: 5 - 40 mg PO QD |
| Rosuvastatin DDI | 1. Avoid using the same time as CYSLOSPORINE, it increased crestor level by 7 - 11 folds 2. Use w/ warfarin = rise in INR 3. Use w/ gemfibrozil = increase crestor by 2 X 4. Use w/ ANTACIDS w/n 2 hrs = decrease crestor plasma levels |
| Rosuvastatin AE | 1. Myalgia 2. asthenia 3. Abd pain, nausea |
| Rosuvastatin counseling | Same as Statins * avoid exposure to sunlight * No pregnancy during therapy * limit alcohol use |
| Rosuvastatin monitor | LFT Lipid panel |
| Rosuvastatin prego category | Category X |
| Simvastatin Brand | Zocor |
| Simvastatin Dosage Form | Tablets 5, 10, 20, 40, 80 mg * Ususal dose is 10 - 40 mg PO QD |
| Simvastatin DDI | 1. May increase Warfarin or digoxin levels 2. Contraindicated in pt taking gemfibrozil, immunosuppressive agents, itraconazole, ketoconazole, HIV drugs, GRAPEFRUIT juice, nefazodone 3. Do not exceed 10 mg daily when used w/ verapamil or diltiazem. 4. Do not exceed 20 mg daily when used w/ Amiodrone, Amlodipine or ranolazine |
| Simvastatin AE | 1. May cause optic nerve degeneration 2. Muscle pain 3. dyspepsia 4. Constipation |
| Simvastatin counseling | Just like other statins 1. Avoid overexposure to sunlight 2. Limit alcohol intake 3. No pregnancy during this therapy |
| Simvastatin monitor | LFT Lipid panel |
| Simvastatin prego category | Category X |
| Bumetanide Brand | Bumex |
| Bumetanide Dosage Form | Tablet: 0.5, 1, 2 mg **** Injection: 0.25 mg/mL **** * Oral: Give 0.5 - 2 mg daily in one or two doses |
| Bumetanide DDI | 1. Do not use w/ Aminoglycosides (Gentamicin, neomycin etc) or cisplatin (chemo drug) bc it could increase the risk of auditory toxicity 2. Be careful in pt w/ hypersensitivity to sulfonamides |
| Bumetanide AE | 1. Dizziness 2. Hypotension 3. Muscle cramps 4. Impaired hearing 5. Hypokalemia 6. hyperuricemia 7. hypochloremia 8. hyponatremia 9. Hyperglacemia 10. Azotemia |
| Bumetanide counseling | 1. May be taken w/ food or milk if GI upset occurs 2. Usual take med in the morning bc of diuresis 3. May cause orthostatic hypotension - use care when standing |
| Bumetanide monitor | K |
| Bumetanide prego category | Category C |
| Clorthalidone Brand | Hygroton |
| Clorthalidone Dosage Form | Tablets: 25 and 50 mg only |
| Clorthalidone DDI | 1. May increase lithium serum level 2. May decrease sulfonylurea hypoglycemia 3. Use w/ diazoxide may cause hyperglycemia 4. electrolyte disturbances may cause DIGI-TALIS-induced arrhythmias |
| Clorthalidone AE | 1. Dry mouth 2. Muscle cramps 3. N and V 4. Anemia 5. Weakness 6. dizziness 7. Orthostatic hypotension 8. Anorexia 9. GI distress 10. Constipation 11. Hyperglycemia 12. Photosensitivity 13. rash 14. transient blurred vision |
| Clorthalidone counseling | 1. May be taken w/ food or milk for if GI upset occurs 2. Avoid excessive exposure to sunlight 3. Usually given in the morning bc of diuresis |
| Clorthalidone monitor | N/A |
| Clorthalidone prego category | Category B |
| Furosemide Brand | Lasix |
| Furosemide Dosage Form | Tablet: 20, 40, 80 mg Oral solution: 10 mg/mL, 40 mg/5mL Injection: 10m |
| Furosemide DDI | 1. Do not use w/ Aminoglycosides (Gentamicin, neomycin etc) or cisplatin (chemo drug) bc it could increase the risk of auditory toxicity 2. electrolyte disturbances may cause DIGITALIS-induced arrhythmias 3. Additive hypokalemia effect may occur w/ other K-depleted drugs. |
| Furosemide AE | 1. Dizziness 2. Orthostatic hypotension 3. dry mouth 4. Hearing loss 5. nausea 6. vomiting 7. Weakness 8. Muscle cramps 9. paresthesia 10. Anemia 11. Hyposensitivity 12. purpura 13. rash 14. hyperglycemia |
| Furosemide counseling | 1. may be taken w/ food if GI upset occurs 2. Usually given in the morning bc of diuresis 3. Don't take OTC cough or cold med, antacids, laxatives or antidiarrheal, w/o talking to your prescriber 4. Avoid overexposure to sunlight 5. May cause orthostatic hypotension |
| Furosemide monitor | K |
| Furosemide prego category | Category C |
| HCTZ Brand | Microzide |
| HCTZ Dosage Form | Tablet: 12.5, 25, 50 mg Capsule: 12.5 mg [blue and white capsule] ** Take 25 -50 mg daily in a single dose or divided oral dose |
| HCTZ DDI | ****Same as Chlorthalidone**** 1. May increase lithium serum level 2. May decrease sulfonylurea hypoglycemia 3. Use w/ diazoxide may cause hyperglycemia 4. electrolyte disturbances may cause DIGITALIS-induced arrhythmias |
| HCTZ AE | 1. Dry mouth 2. Muscle cramps 3. Orthostatic Hypotension 4. dizziness 5. weakness 6. anorexia 7. Anemia 8. Nausea and Vomiting 9. Diarrhea and constipation 10. hyperglycemia 11. Photosensitivity 12. rash 13. transient blurred vision |
| HCTZ counseling | 1. May be taken w/ food or milk if GI upset occurs 2. Take early in the morning bc of diuresis 3. Avoid excessive exposure to Sunlight |
| HCTZ monitor | BP K |
| HCTZ prego category | Category B |
| Metolazone Brand | Zaroxolyn |
| Metolazone Dosage Form | Tablets: 2.5, 5, 10 mg * Give 5 - 20 mg QD |
| Metolazone DDI | 1. Avoid using w/ furosemide cus of potentially serious loss of fluid and electrolytes 2. Additive effects w/ antihypertensive meds 3. May decrease effectiveness of methenamine 4. Non steroidal anti-inflammatory agents may decrease Zaroxolyn effectiveness 5. May increase the effect of neuromuscular blocking agents 6. May increase lithium serum level 7. May decrease sulfonylurea hypoglycemia 8 Use w/ diazoxide may cause hyperglycemia 9. electrolyte disturbances may cause DIGITALIS-induced arrhythmias. |
| Metolazone AE | 1. Dry mouth 2. Muscle cramps 3. Orthostatic Hypotension 4. dizziness 5. weakness 6. anorexia 7. Anemia 8. Nausea and Vomiting 9. Diarrhea and constipation 10. hyperglycemia 11. Photosensitivity 12. rash 13. transient blurred vision 14. joint pain or gout attack |
| Metolazone counseling | 1. May take w/ food or milk if GI upset occurs 2. Take in the morning bc of diuresis 3. Avoid excessive exposure to sunlight |
| Metolazone monitor | Na K |
| Metolazone prego category | Category B |
| Spironolactone Brand | Aldactone |
| Spironolactone Dosage Form | Tablets 25, 50, 100 mg ** Give initially 100 mg QD w/ adjustment at 5 day intervals to a maintenance dose of 25 - 200 mg per day |
| Spironolactone DDI | 1. Use w/ captoril and other K-sparing could result in hyperkalemia |
| Spironolactone AE | 1. Paresthesia 2. Weakness 3. Mental confusion 4. Dry mouth 5. Muscle cramps 6. Drowsiness 7. Diarrhea 8. Headache 9. Amenorrhea 10. gynecomastia 11. nausea/vomiting |
| Spironolactone counseling | 1. May take w/ food or milk if GI upset occurs 2. Take in the morning bc of diuresis 3. May cause drowsiness, be careful when operating machinery or need mental alertness |
| Spironolactone monitor | Fluid and Electrolyte imbalance BEERs List >25mg/day |
| Spironolactone prego category | Category B |
| Torsemide Brand | Demadex |
| Torsemide Dosage Form | Tablets 5, 10, 20 100 mg * Give initial dose of 5 - 10 mg PO QD |
| Torsemide DDI | 1. Salicylate excretion may decrease 2. caution w/ pt taking non-steroidal inflammatory agents due to possible renal dysfunction. 3. Indomethacin and probenecid may decrease effectiveness of torsemide 4. Cholestyramine may decrease oral bioavailability if given at the same time 5. Other diuretics have been reported to increase the toxicity of lithium and Aminoglycosides |
| Torsemide AE | Excessive urination |
| Torsemide counseling | 1. May take w/ food or milk if GI upset occurs 2. Take in the morning bc of diuresis 3. Don't take OTC cough or cold med, antacids, laxatives or antidiarrheal, w/o talking to your prescriber |
| Torsemide monitor | K Electrolytes |
| Torsemide prego category | Category B |
| Isosorbide Mononitrate Brand | Imdur |
| Isosorbide Mononitrate Dosage Form | Tablets (ER) 30 (peach color), 60, 120 mg ** Normal daily dose is 30 -120 mg QD at A.M. |
| Isosorbide Mononitrate DDI | 1. Alcohol may increase hypotensive effects 2. Additive effects may occur w/ other vasodilators especially CCBs |
| Isosorbide Mononitrate AE | 1. Headache 2. dizziness 3. rash 4. cutaneous vasodilation w/ flushing, nausea, vomiting, dry mouth, tinnitus, blurred vision, acne or anxiety |
| Isosorbide Mononitrate counseling | 1. May cause flushing and dizziness 2. May cause headache = sign of effectiveness (use ASA or APAP to trt headache, prn) 3. Swallowed whole or halved, do not crush or chew 4. Avoid alcohol when taking Imdur |
| Isosorbide Mononitrate monitor | BP Volume depletion |
| Isosorbide Mononitrate prego category | Category B |
| Nitroglycerin Brand | Nitrosatat Nitroquick |
| Nitroglycerin Dosage Form | Sublingual and Injectable Tablets, sublingual: 0.3, 0.4, 0.6 mg Injection: 5 mg/mL |
| Nitroglycerin DDI | 1. Heparin effect may decrease 2. Sildenafil citrate may increase hypotensive effect 3. dihydorergotamine may have increased effect |
| Nitroglycerin AE | 1. Transient headache 2. nausea and vomiting 3. dizziness 4. Flushing of face or neck 5. rapid pulse |
| Nitroglycerin counseling | 1. Store away from sunlight in a glass or metal container 2. Avoid alcohol, it may aggravate angina 3. Pt shd sit down when taking sublingual nitrostat to avoid lightheadedness and fainting 4. To avoid leaching, dispense tablets in original container (glass) and counsel on keeping them in the original container (to avoid leaching) 5. Close container tightly after use 6. Tablet taste bitter (tingling sensation) upon use, if not replace w/ a new supply. 7. Dissolve tablet under the tongue (do not swallow) at the first sign of attach. Do not wait until angina is severe 8. After placing first tablet under tongue, if angina is not relieved w/n 5 minutes, dissolve the second tablet under tongue and then a third tablet if necessary. 9. If pain continues or increase, notify physician or go to ER |
| Nitroglycerin monitor | BP (hypotension) hypovolemia |
| Nitroglycerin prego category | Category C |
| Ranolazine Brand | Ranexa |
| Ranolazine Dosage Form | Tablets (ER) 500 and 1000 mg |
| Ranolazine DDI | *** Lots of drugs see the drug card |
| Ranolazine AE | 1. dizziness 2. headache 3. constipation 4. nausea |
| Ranolazine counseling | 1. May cause dizziness 2. May cause lightheadedness 3. May cause fainting spell 4. Swallow whole, do not crush, chew or break tablets 5. Inform your PCP if taking OTC medication |
| Ranolazine monitor | BP RFT QT interval prolongation |
| Ranolazine prego category | No data available for prego and lactation |
| Triamterene w/ HCTZ Brand | Dyazide Maxzide |
| Triamterene w/ HCTZ Dosage Form | Dyazide capsule = 37.5 triamterene, 25 mg HCTZ Maxzide-25 tablet = 37.5 mg triamterene, 25 mg HCTZ Maxzide tablet = 75 mg triamterene, 50 mg HCTZ **Take 1 - 2 doses twice a day |
| Triamterene w/ HCTZ DDI | 1. Toxic effects of cardiac glycosides, diazoxide and lithium may increase 2. Hyperkalemia may result from use of K-sparing diuretics, K supplement or ACEIs 3. Sulfonylureas may have decreased effects |
| Triamterene w/ HCTZ AE | 1. Dry mouth 2. MUSCLE CRAMPS 3. Orthostatic Hypotension 4. dizziness 5. WEAKNESS 6. Impotence 7. Nausea and Vomiting 8. Diarrhea and constipation 9. hyperglycemia 10. Photosensitivity 12. RASH 13. transient blurred vision |
| Triamterene w/ HCTZ counseling | 1. Use in the morning bc of diuresis 2. May take w/ food or milk if GI upset occurs 3. Avoid prolonged exposure to sunlight |
| Triamterene w/ HCTZ monitor | K |
| Triamterene w/ HCTZ prego category | Category C |
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