BMS10-1017 - Blood Cells: RBC WBC and platelets

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Review of blood cell types: erythrocytes, lymphocytes, granulocytes, monocytes and platelets. Plasma as the fluid matrix of the formed elements of blood. Describe the different types of blood cells, their origin, lifespan and functions Briefly consider plasma as the fluid matrix of blood
Evian Chai
Flashcards by Evian Chai, updated more than 1 year ago
Evian Chai
Created by Evian Chai over 4 years ago
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Question Answer
What is the size and shape of a red blood cell? 7 uM Biconcave disc
RBCs can only undergo anaerobic metabolism of glucose because They have no organelles
...diffrentiates to.... after ejecting ...., which then becomes a RBC after.... Normocyte-->Reticulocyte after nucleus ejected Organelles lost
What do platelets (thrombocytes) look like and what do they do? What are they from and where? 1. Biconcave dark granules They play a role in haematostasis /maintaining blood vessels by forming clots 2. Formed from fragmentation of macrophages in bone marrow
What are the precursors of platelets and what do they look like? What fuses together to become vesicles that form platelets? 1. Macrophages Giant cells with a single irregular nucleus 3. Endoplasmic reticulum tubules
Eosinophils, Basophils and Neutrophils are what kind of leukocyte? Granulocytes (multi lobed)
Monocytes and Lymphocytes are what kind of leukocyte? Agranulocytes (one nuclues, no lobes)
Which leukocyte has many lobes, makes up 90% of the granulocytes, release granules for phagocytic activity, and die after a single burst of activity? Neutrophils
Which leukocyte is bi-lobed, stains blue, and releases inflammatory histamine? Basophil
Which leukocyte is bi-lobed, stains pink, releases antihistaminases in response to allergy/infection, and is phagocytic? Eosinophil
Which leukocyte is largest, has a horse shoe shaped nuclues, presents antigens, and does phagocytosis? Monocytes
What is the relationship between monocytes and macrophages? Monocytes become macrophages after leaving circulation
Which leukocyte stains purple, has a single large round nucleus, and primarily provides specific immunity? What are the three types? Lymphocytes 1. T cells flag 2. B cells release antibodies 3. Natural Killer cells
At 2-2.5 weeks in utero, where are RBCs? Outside embryo in extraembryonic membrane as blood islands
At 5 weeks, where do the blood islands migrate to? The liver, to start producing RBC and WBC
Where do RBC/WBC production move to 5 months in utero? Bone marrow, but can migrate to liver/spleen if needed
What is plasma? What is it made of? 1. Fluid component of blood 2. Aqueous composition of salts, nutrients, plasma protein
What are the three plasma proteins? 1. Albumin (transporters) 2. Fibrinogen (fibrin precursor) 3. Globulins (immunoglubulin-->antibodies)
Which cells have a lymphoid progenitor instead of myeoid? Small lymphocytes (B/T) Large lymphocytes (Natural killer)
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