sclerodermie

Description

Flashcards on sclerodermie, created by Marinescu Mircea on 19/06/2015.
Marinescu Mircea
Flashcards by Marinescu Mircea, updated more than 1 year ago
Marinescu Mircea
Created by Marinescu Mircea over 9 years ago
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Question Answer
SCLERODERMIA Caracteristici: • vasculopatie functionala si structurala • fibroza, lez. degenerative piele, org. interne
Epidemiologie • Prevalenta- • Incidenta • Frecventa >F 4 cazuri /1milion(1975) ; 126 cazuri/1milion dupa 1975 18-29 cazuri/1 milion/an F/B=3/1
• FACTORI MEDIU- uleiuri industriale hidrocarburi, pulberi siliciu medicamente, infectii
TERENUL GENETIC HLA DR2, DR3 anomalii cromozomiale gena fibrilina I
FACTORI IMUNI AAN, TCD4+, IL2 reactie grefa contra gazda (microchimerism fetal)
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