PHAR 422 Midterm II - Heterocycles

Question	Answer
Oxirane Image: Image (binary/octet-stream)	Oxirane
Aziridine Image: Aziridine (binary/octet-stream)	Aziridine
Thiirane Image: Thiirane (binary/octet-stream)	Thiirane
Image: Oxetane (binary/octet-stream)	Oxetane
Image: Azetidine (binary/octet-stream)	Azetidine
Image: Thietane (binary/octet-stream)	Thietane
Image: 1,3 Dithietane (binary/octet-stream)	1,3-dithetane
Oxygen prefix	Oxa
Sulfur Prefix	Thia
Nitrogen Prefix	Aza
Unsaturated, Ring Size: 3 Suffix	irene
saturated, ring size: 3 suffix	irane
unsaturated, ring size: 4 suffix	ete
saturated, ring size: 4 suffix	etane
unsaturated, ring size: 5 suffix	ole
saturated, ring size: 5 suffix	olane
unsaturated, ring size: 6 suffix	ine
saturated, ring size: 6 suffix	inane
unsaturated, ring size: 7 suffix	epine
saturated, ring size: 7 suffix	epane
unsaturated, ring size: 8 suffix	ocine
saturated, ring size: 8 suffix	ocane
saturated, ring size: 3, Nitrogen suffix	iridine
saturated, ring size: 4, Nitrogen suffix	etidine
saturated, ring size: 5, Nitrogen suffix	olidine
Which heteroatom is numbered 1 when more than 1 is present?	The heteroatom with higher atomic number
Image: Penam (binary/octet-stream)	penam
Image: Carbapenam+Final (binary/octet-stream)	carbapenam
Image: Oxapenam (binary/octet-stream)	oxapenam
Image: Penem (binary/octet-stream)	penem
Image: Carbapenem (binary/octet-stream)	carbapenem
Image: Clavam (binary/octet-stream)	clavam
Image: Monobactam (binary/octet-stream)	monobactam
Image: Cephem (binary/octet-stream)	cephem
Image: Carbacephem (binary/octet-stream)	carbacephem
Image: Oxacephem (binary/octet-stream)	oxacephem
-penem drugs	antibacterial antibiotics
-cillin drugs	penicillins
-bactam drugs	beta-lactamase inhibitors
What type of inhibitors are beta-lactam antibiotics?	Covalent irreversible
Reactivity of beta-lactams order	(least) monobactams < cephems < penams < carbanpenems < clavams (most)
Image: Furan (binary/octet-stream)	furan
Image: Tetrahydrofuran (binary/octet-stream)	tetrahydrofuran
Image: Thiophen (binary/octet-stream)	thiophene
Image: Tetrahydrothiophene (binary/octet-stream)	tetrahydrothiophene
Image: Pyrrole (binary/octet-stream)	pyrrole
Image: Pyrrolidine (binary/octet-stream)	pyrrolidine
Image: Imidazole (binary/octet-stream)	imidazole
Image: Thiazole (binary/octet-stream)	thiazole
Image: Oxazole (binary/octet-stream)	oxazole
Image: Isoxazole (binary/octet-stream)	isoxazole
Image: Isothiazole (binary/octet-stream)	isothiazole
Image: 1,2,3 Triazole (binary/octet-stream)	1,2,3-triazole
Image: 1,2,4 Triazole (binary/octet-stream)	1,2,4-triazole
Image: Tetrazole (binary/octet-stream)	tetrazole
Image: Indole (binary/octet-stream)	indole
Image: Benzothiophene (binary/octet-stream)	benzothiaphene
Image: Benzoimidazole (binary/octet-stream)	benzoimidazole
Image: Benzothiazole (binary/octet-stream)	benzothiazole
Image: Benzoxazole (binary/octet-stream)	benzoxazole
Image: Benzotriazole (binary/octet-stream)	benzotriazole
Image: Piperidine (binary/octet-stream)	piperidine
Image: Morpholine (binary/octet-stream)	morpholine
Image: Pyridine (binary/octet-stream)	pyridine
Image: Pyridazine (binary/octet-stream)	pyridazine
Image: Pyrimidine (binary/octet-stream)	pyrimidine
Image: Pyrazine (binary/octet-stream)	pyrazine
Image: Cinnoline (binary/octet-stream)	cinnoline
Image: Quinoline (binary/octet-stream)	quinoline
Image: Isoquinoline (binary/octet-stream)	isoquinoline
Image: Quinazoline (binary/octet-stream)	quinazoline
Image: Quinoxaline (binary/octet-stream)	quinoxaline
Image: Napthalene (binary/octet-stream)	napthalene

Oxirane

Image: Image (binary/octet-stream)

Oxirane

Aziridine

Image: Aziridine (binary/octet-stream)

Aziridine

Thiirane

Image: Thiirane (binary/octet-stream)

Thiirane

Image: Oxetane (binary/octet-stream)

Oxetane

Image: Azetidine (binary/octet-stream)