Analgesia

Description

analgesia definitions and drugs
Sherry Grisham-Cushing
Flashcards by Sherry Grisham-Cushing, updated more than 1 year ago
Sherry Grisham-Cushing
Created by Sherry Grisham-Cushing over 8 years ago
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Resource summary

Question Answer
Unpleasant sensory or emotion experience pain
Pain that occurs after the initial tissue injury pathologic pain
Absence of pain in the presence of a painful stimulus analgesia
afferent nerve ending preferentially sensitive to noxious stimuli nocicepter
The physiologic process of transduction, transmission and modulation of nerve signals generated by nocicepters nociception
Pain resulting from a stimulus that isn't normally painful allodynia
Hyperexcitability of neurons in the spinal cord after repeated high-intensity nociceptive impulses Wind-up
Pain from internal organs Visceral Pain
Pain from skin, SQ muscles, bones and joints, and peritoneum Somatic Pain
Pain felt in a body part other than that in which it originates Referred Pain
Pain which has an abrupt onset and a relatively short duration, which ends when the tissue is healed Acute Pain
Pain which is present after the tissue has healed, with a long duration Chronic Pain
The use of 2 or more analgesic agents that differ in their mechanism of action to treat pain Multimodal or Balanced Analgesia
Establishment of analgesia before the onset of painful stimuli which can prevent windup Pre-emptive Analgesia
This is the most effective analgesic family, commonly used in veterinary hospitals Opioids
This drug is a pure opioid agonist which other opioids are measured against. The "gold standard" Morphine
This opioid drug treats severe pain and has many similarities to morphine with fewer side effects (especially hypotension) Hydromorphone
This potent opioid analgesic has a rapid onset and a short duration of action. Routes include IV, CRI, IM and transdermal Fentanyl
This drug is a partial mu agonist, is most effective in felines, and is now available in a drug lasting 24 hours Buprenorphine
This mixed agonist/antagonist provides short analgesia but longer sedation. Butorphanol
This opioid agonist/antagonist can act to reverse opioid drugs at the mu receptor Butorphanol
Name 2 Opioid Reversal agents and the receptor at which they work Naloxone, Butorphanol both work at the mu receptor
Oral synthetic opioid which inhibits reuptake of serotonin and norepinephrine, contributing to analgesia Tramdaol
This family of drug modifies the inflammatory response NSAID
The primary side effect of the NSAID family of drugs is GI Ulceration
This analgesic drug family should not be administered to patients who become hypotensive intra-operatively NSAIDs
Name several NSAIDs frequently prescribed in the veterinary office carprofen, deracoxib, meloxicam,firocoxib
This family of drugs is a reliable sedative in the preanesthetic time period, providing visceral and somatic analgesia alpha-2 agonists
This family of analgesic drugs acts synergistically with opioids and improves intensity and duration of analgesia alpha-2 agonists (xylazine and dexmedetomidine)
This family of analgesic drugs disrupts neural transmission of information Local Anesthetics
Name 2 drugs which have NMDA receptor antagonist action providing analgesia Ketamine, Amantadine
This drug was originally used as an anticonvulsant and acts by down-regulating calcium channels Gabapentin
This drug is used in humans to treat neuropathic and maladaptive pain Gabapentin
This tricyclic antidepressent can be used to treat neuropathic pain Amitriptyline
There is speculation that this drug's inhibition of substance P may play a role in analgesia Maropitant (Cerenia)
This drug is used to treat osteosarcoma pain Biphosphonate
This family of drugs treats pain by reducing inflammation and can be dangerous if administered with NSAID's Corticosteroids
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