PHRM 590 | Pharmacy Practice 1 | Top 200 Drugs

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PHRM 590 | Pharmacy Practice 1 | Top 200 Drugs
Austin Thomas
Flashcards by Austin Thomas, updated more than 1 year ago
Austin Thomas
Created by Austin Thomas about 8 years ago
59
1

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Question Answer
Clonazepam Klonopin Anti-Anxiety & Anti-Seizure Panic Disorders, Seizures (Lennox-Gastaut) 0.5mg - 2mg Dosage Benzodiazepines (Inhibit NT GABA) Tired, NO EtOH, PCP if severe ADR, HABIT FORMING, DON'T STOP ABRUPTLY
Gabapentin Neurontin Anti-Convulsant, & Anti-Neuralgic Seizures, Neuralgia 100mg - 600mg Dosage UNKOWN MOA, Related to GABA Tired, NO EtOH, PCP if severe ADR, w/o regards to food, DON'T STOP ABRUPTLY
Pregabalin Lyrica Anti-Convulsant & Anti-Neuralgic DM Neuropathy Pain, Seizures, Fibromyalgia 25 mg - 300 mg Dosage May relate to binding of α-2-δ sites at CNS Tired, NO EtOH, PCP if severe ADR, Unexplained Muscle Pain, w/o regards to food, Do not stop abruptly
Topiramate Topamax Anti-Epileptic Seizures & Prophylaxis of Migraines 15 mg - 100 mg Dosage UNKOWN MOA, May block Na Action Potentials, ↑ Gaba Activation to Induce Cl flux into Neuron, Antagonizes Kainate Tired, NO EtOH, PCP if severe ADR, Blurred Vision or Periorbital Pain, w/o regards to food, Hydrate to avoid Kidney Stones
Lamotrigine Lamictal Anti-Epileptic Seizures & Bipolar 1 Mood Episodes/Disorder 5 mg - 300 mg Dosage UNKOWN MOA, May inhibit Voltage sensitive Sodium Channels, modulating glutamate & other neurotransmitters Tired, PCP if severe ADR, hypersensitivity for rash, pregnancy, or lactation, Do not change dosage without PCP
Benztropine Cogentin Anti-Parkinsonism Parkinson's Disease 0.5 mg - 2 mg Inhibits Cholinergic & Histamine Receptors NO EtOH, PCP if severe ADR, Take w/ Food/Milk. Don't stop sudden, Avoid Hot Weather Exposure.
Ropinerole HCl Requip Anti-Parkinsonism Parkinson's & Restless Leg Syndrome 0.25-12mg Dosage DA Agonist, Stimulates DA Receptors Tired/Dizzy, NO EtOH, PCP if start/stop smoking, Take w/o regard to food. Don't stopsudden, Orthostatic Hypotension, Hallucinations possible.
Carbidopa/Levodopra Sinemet Anti-Parkinsonism Parkinson's Disease 10/100-50/200mg Dosage LDopa: Cross BBB, converts to DA CDopa: Inhibits COMT, ↑ L-Dopa Contact PCP if severe ADR, Take with food = avoid GI upset. Don't stop sudden, AVOID Vitamin B6
Pramipexole Mirapex Anti-Parkinsonism Parkinson's & Restless Leg Syndrome 0.125-4.5mg Dosage DA Receptor Agonist Tired/Dizzy. Contact PCP if severe ADR or Vision Problems, Take with food = avoid GI upset. Hallucinations possible, Orthostatic Hypotension
Memantine HCl Namenda Alzheimer's Agent Alzheimer's Disease 5-28mg Dosage May uncompetitively bind NMDA Receptors Contact PCP if severe ADR, Take with food = avoid GI upset. TAKE BEFORE BED
Donepezil HCl Aricept AD Agent Alzheimer's Disease 5-10mg Dosage AChE Inhibitor Contact PCP if severe ADR, w/o regards to meals. Take before bed
Diazepam Valium Anti-Anxiety Anxiety, EtOH Withdrawl, OCD, Pre-Op. 2-10mg Dosage & Rectal Gel Benzodiazepine, Facilitates Inhibit. NT Gaba Tired. No EtOH. Contact PCP if severe ADR, If dose missed, skip and return following day! Dilute Gel before using. HABIT FORMING
Lorazepam Ativan Anti-Anxiety Anxiety, Insomnia, Pre-OP Sedation 0.5-2mg Dosage Benzodiazepine, Facilitates Inhibit. NT Gaba Tired. No EtOH. Contact PCP if severe ADR, If dose missed, skip and return following day. HABIT FORMING
Quetiapine Seroquel Anti-Psychotic SZ. Major Depressive Disorder 25-400mg Dosage 5HT-1A & 5HT-2A Antagonists DA-1 & DA-2 Antagonists H1, α-1, α-2 Antagonists Tired. Contact PCP if severe ADR, If dose missed-skip and return following day. w/o regards to meals. DO NOT CHANGE DOSE OR CHEW TABLET
Ziprazidone HCl Geodon Anti-Psychotic SZ, Acute Agitation, Acute/Maintenance of Mania or Mixed Episodes 20-80mg Dosage 5HT-2 Antagonist & DA-2 Antagonist Tired. No EtOH. Contact PCP if severe ADR, Tell PCP of CV condition or other Meds. If dose missed-skip and return following day. Take with food. May take several weeks to work. Heat Exposure and Dehydration
Olanzapine Zyprexia Anti-Psychotic Psych Manifestation, Acute Mixed Manic Episodes, Agitation SZ 2.5-20mg Dosage 5HT-2 Antagonist & DA-2 Antagonist Tired. Contact PCP if severe ADR, If dose missed-skip and return following day. w/o regards to meals. Do not change dose
Ariprazole Abilify Anti-Psychotic SZ, Acute Mania/Mixed Episode 2.5-30mg dosage 5HT-2 Antagonist & DA-2 Partial Agonist Tired. No EtOH. Contact PCP if severe ADR, If dose missed-skip & return following day. Avoid Heat Exposure & Dehydration
Haloperidol Haldol Anti-Psychotic Psych Manifestations, Tics, Tourettes 0.5-20mg dosage Competitively blocks DA receptors Tired. No EtOH. Contact PCP if severe ADR, If dose missed-take ASAP. Do not d/c. Photosensitive/Heat Intolerant
Paliperidone Invega Anti-Psychotic SZ, Acute Mania/Mixed Episode 1.5-9mg Dosage Active Metabolite of Risperidone 5HT-2 Antagonist & DA-2 Antagonist Tired. No EtOH. Contact PCP if severe ADR, If dose missed-take ASAP. w/ food or milk for GI. Risk of fainting = care when sitting up Avoid Sun and High Temp
Risperidone Risperidal Anti-Psychotic SZ, Acute Mania/Mixed Episode, Autism 0.25-4mg dosage 5HT-2 Antagonist & DA-2 Partial Agonist No EtOH. Contact PCP if severe ADR, If dose missed-take ASAP. Food or Milk for GI. Risk of fainting = care when sitting up Avoid Sun and High Temp
Bupropion HCl Wellbutrin Anti-Depressant Depression & Smoking Cessation 75-450mg Dosage DNRI (DA & NE Reuptake Inhibitor) No EtOH. Contact PCP if severe ADR & OTC use, Risk of Seizures. If dose missed-take ASAP. Absolutely NO Doubling Dosage. weight gain, mood changes, suicidal thoughts, may take 2 weeks to improve
Amitriptyline HCl Elavil Anti-Depressant Depression ONLY 10-150mg Dosage TCA (NE & 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR, If dose missed-skip & return. Don't d/c
Duloxetine HCl Cymbalta Anti-Depressant Major depressive disorder, Neuropathic Pain, Generalized Anxiety, Chronic N.Musc. Pain 20-60mg Dosage Potent NE & 5HT Reuptake Inhibitor Slight inhibitor of DA Reuptake Tired, No EtOH. Contact PCP if severe ADR & OTC use. If dose missed-skip & return. May take up to 4 weeks to work. Don't d/c abruptly. Suicidal Thoughts
Venlafaxine HCl Effexor Anti-Depressant Depression, Gen. Anxiety, Social Anxiety 25-100mg Dosage Potent NE & 5HT Reuptake Inhibitor Slight inhibitor of DA Reuptake No EtOH. Contact PCP if severe ADR & OTC. Swallow capsules whole, no chewing. don't d/c without PCP. Mood changes, Suicidal thoughts. May take 2 weeks to work
Paroxetine HCl Paxil Anti-Depressant Depression/OCD/P. Disorder/Social Anxiety 10-40mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR & OTC. Don't d/c abruptly, be sure to take only once every 24 hours. Behavior & Mood changes, such as suicidal thoughts. May take 2 weeks to work. Swallow capsules whole
Trazodone HCl Desyrel Anti-Depressant Depression ONLY 50-300mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR. Don't d/c abruptly, be sure to take only once every 24 hours. Behavior & Mood changes, such as suicidal thoughts. If dose missed, skip and return. May take 2 weeks to work. Swallow capsules whole
Fluoxetine HCl Prozac Anti-Depressant Depression, OCD, Bulimia Nervosa, Panic DIsorder 10-60mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR. Don't d/c abruptly, Behavior & Mood changes, such as suicidal thoughts. If dose missed, take ASAP. May take 2 weeks to work. Swallow capsules whole. Don't stop abruptly
Escitalopram Oxalate Lexapro Anti-Depressant Depression, Generalized Anxiety Disorder 5-20mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR & OTC. Don't d/c abruptly, Behavior & Mood changes, such as suicidal thoughts. If dose missed, skip and return. May take 2 weeks to work. Swallow capsules whole. Don't stop abruptly
Sertraline HCl Zoloft Anti-Depressant Depression, OCD, Panic Disorder, Social Anxiety 25-100mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR & OTC. Don't d/c abruptly, Behavior & Mood changes, such as suicidal thoughts. If dose missed, skip and return. May take 2 weeks to work. Swallow capsules whole. Don't stop abruptly. Therapy must be continued to improve.
Citalopram HBr Celexa Anti-Depressant Depression 10-40mg Dosage Selective 5HT Reuptake Inhibitor Tired, No EtOH. Contact PCP if severe ADR & OTC. Don't d/c abruptly, Behavior & Mood changes, such as suicidal thoughts. If dose missed, skip and return. May take 2 weeks to work..
Methylphenidate HCl Ritalin, Methylin, Concerta, Metadate CD Immediate Release & Extended Release CNS Stimulant Attention Deficit Disorder 5-20mg Dosage Activates Brain stem and cortex Contact PCP if severe ADR. Missed dose, skip and return. Take early evening for insomnia. Habit forming
Amphetamine & Dextroamphetamine Salts Adderall XR CNS Stimulant Narcolepsy & ADHD 5-30mg Dosage Unknown Direct Action on Adrenergic Receptors, release of NE Dizzy, Contact PCP if severe ADR. Missed dose, skip and return. Do not exceed dosage. No refills and habit forming.
Mometasome Nasonex Anti-Allergy Preventative of Season Allergies Rhinitis 50mcg Dosage Adrenocorticoid; binding to receptors, stimulate transcription of DNA Contact PCP if severe ADR. Missed dose, take ASAP. If no improvement after 3 weeks, use at regular amounts to clear nasal passages first.
Fluticasone Flonase Anti-Allergy Preventative of Season Allergies Rhinitis 50mcg Dosage Adrenocorticoid; binding to receptors, stimulate transcription of DNA Contact PCP if severe ADR. Missed dose, take ASAP. If no improvement after 3 weeks, use at regular amounts to clear nasal passages first.
Psudoephedrine Sudafed
Iprotropium Atrovent Anti-Allergy & COPD Agent Bronchospasm, Rhinorrhea "Associated with Allergic Rhinitis" 17mcg Dosage Anti-Cholinergic Missed Dose, take ASAP No Double Dose
Iprotropium & Albuterol Combivent COPD Agent COPD & Asthma 18mcg Stimulates Adenylyl Cyclase = ↑ cAMP "Relaxation of Smooth Muscle Contact PCP for severe ADR. Don't exceed dose, avoid eye contact. Follow nebulizer instructions, at regular intervals
Budesonide Pulmicort COPD Agent COPD & Asthma 80mcg Corticosteroids; inhibiting MAST cells, eosinophils, neutrophils, macrophages, lymphocytes, and mediators (histamine, eicosanoids, leukotrienes, cytokines) Contact PCP is not working like it should or severe ADR. Don't exceed dose, avoid eye contact. Rinse mouth out after use. Follow inhalation direction. Missed dosage, skip and return. Not for immediate relief.
Fluticasone & Salmeterol Advair CODP Agent & Anti-Asthmatic Asthma & COPD 100/50-500/50 Corticosteroids; inhibiting MAST cells, eosinophils, neutrophils, macrophages, lymphocytes, and mediators (histamine, eicosanoids, leukotrienes, cytokines) Contact PCP for severe ADR or condition worsens. Missed dosage, skip and return. Avoid contact with eyes, rinse mouth. Use regularly (not for right-away relief) Be sure to follow directions.
Montelukast Singular Anti-Asthmatic & Anti-Allergy Prevention of Asthma Outbreaks, Allergic Season Rhinitis 4-10mg Dosage Binds to receptor, inhibits LTD4 Leukotrienes Contact PCP for severe ADR. Missed dosage-take ASAP. Use regularly (not for right-away relief). Contains Phenylalanine
Theophyline THEO-24 Anti-Asthmatic & Bronchodilator Bronchial Asthma 100-400mg Dosage Inhibits Phosphodiesterase, ↑ cAMP Contact PCP for severe ADR. Missed dosage-skip & return. Empty stomach. Taken at regular intervals, avoid xanthine consumption. Swallow whole
Albuterol Proventil HFA, Ventolin HFA, Proair HFA Bronchodilator Bronchospasms 90mcg Stimulates Adenylyl Cyclase, ↑ cAMP. Relaxation of smooth muscle Don't take more often than written. Contact PCP, if treatment becomes less effective, avoid contact with eyes, and shake medication. Follow directions, clean mouth piece once weekly
Methylprednisolone Medrol Anti-Inflammatory Various allergic & inflammation diseases 2-32mg Dosage Adrenocorticoids Contact PCP, if severe ADR, if dose missed-take ASAP. Take with food/milk for GI, and shake medication. Don't d/c medication, take as prescribed only
Prednisone Deltasone Anti-Inflammatory Various allergic & inflammation diseases 1-20mg Dosage Adrenocorticoids Contact PCP, if severe ADR, if dose missed-take ASAP. Don't d/c medication, take as prescribed only
Tamsulosin Flomax Prostate Anti-Inflammatory Agent BPH 0.4mg Dosage α-adrenergic receptor blocker for prostate Contact PCP, if severe ADR, if dose missed-skip and return. take 30 minutes after meal, don't d/c medication
Doxazosin Cardura Prostate Anti-Inflammatory Agent HTN, BPH 1-8mg Dosage α-1-adrenergic receptor antagonist Dilation of blood vessels, ↓ blood pressure Contact PCP, if severe ADR. Take first dosage at bedtime, risk of fainting. Avoid activities that require alertness 12 hours after admin. Avoid OTC, unless PCP
Atenolol Tenormin Anti-HTN HTN 25-100mg Dosage Block β-1-adrenergic receptors; ↓ HF ↓ BP, Inhibits Tachycardia Dizzy. Contact PCP if severe ADR. Missed dose-take ASAP. Take with food/milk for GI. Don't d/c. Masks hypoglycemia symptoms (DM).
Carvedilol Coreg Anti-HTN HTN, Heart Failure 3.125-25mg Dosage Block β-1-adrenergic receptors; ↓ Cardiac Output ↓ Tachycardia Dizzy. Contact PCP if severe ADR. Missed dose-take ASAP. Take with food to avoid Orthostatic Hypotension. Contact Lens wearing ↓ lacrimation. Don't d/c. Masks hypoglycemia symptoms (DM). Avoid Cough, Cold, Allergy, OTC Medications
Metoprolol Succinate Toprol XL Anti-HTN HTN, Angina Pectoris 25-200mg Dosage Block β-1-adrenergic receptors; ↓ HR ↓ Cardiac Output ↓ BP ↓ Tachycardia Dizzy. Contact PCP if severe ADR & HF Symptoms Worsen. Missed dose-take ASAP. Don't d/c. Masks hypoglycemia symptoms (DM). Swallow whole
Metoprolol Tartrate Lopressor Anti-HTN HTN, Acute Myocardial Infarction 25-100mg Dosage Block β-1-adrenergic receptors; ↓ HR ↓ Cardiac Output ↓ BP ↓ Tachycardia Dizzy. Contact PCP if severe ADR. Missed dose-take ASAP. Don't d/c. Masks hypoglycemia symptoms (DM)
Terazosin Hytrin Anti-HTN HTN, BPH 1-10mg Dosage α-1 adrenergic inhibitor, vasodilation Avoid Alert Activities 12 hours post admin. Contact PCP if severe ADR. Missed dose-take ASAP. Don't d/c, take at bedtime, avoid cough, cold, allergy OTC medcations
Propanolol Inderal-LA Anti-HTN HTN, Angina Pectoris, Migraines 10-160mg Dosage Block β-adrenergic receptors; ↓ HR ↓ Cardiac Output ↓ BP ↓ Tachycardia Tired. Contact PCP if severe ADR. Missed dose-take ASAP. Don't d/c, watch out for hypoglyemic symptoms (DM), Avoid Cough/Cold/Allergy OTC medications. Food/Milk for GI
Tizanidine Zanaflex Muscle Relaxant Spasticity 2.4-6mg Dosage α-2 agonist & Adrenergic Receptor Tired/Dizzy. Contact PCP if severe ADR. Missed dose-take ASAP. Food/Milk for GI
Celecoxib Celebrex NSAIDs Osteoarthritis & Acute Pain 50-400mg Dosage Cox inhibitor = decrease prostaglandins Contact PCP if serious ADR or signs of Hepatic failure. If dose missed-skip & return (no-double). 2 weeks to work. Take with food/milk for GI help
Diclofenac Voltaren NSAIDs Acute & Chronic Rheumatoid Arthritis 25-75mg Dosage Cox inhibitor = decrease prostaglandins EtOH increases ulcer effects. Contact PCP if serious ADR. If dose missed-take ASAP (no-double). Take with food/milk for GI help. Avoid Aspirin & Swallow whole
Nabumetone Ralafen NSAIDs Osteoarthritis & Acute Pain 500-750mg Dosage Cox inhibitor = decrease prostaglandins EtOH increases ulcer effects. Contact PCP if serious ADR. If dose missed-skip & return (no-double). 2 weeks to work. Take with food/milk for GI help
Ibuprofen Motrin NSAIDs Mild to Moderate Pain, Rheumatoid Arthritis 400-800mg Dosage Cox inhibitor = decrease prostaglandins EtOH increases ulcer effects. Contact PCP if serious ADR or rash. If dose missed-take ASAP (no-double). 2 weeks to work. AVOID ASPIRIN
Indomethacin Indocin NSAIDs Osteoarthritis & Acute Pain 25-50mg Dosage Cox inhibitor = decrease prostaglandins Tired, EtOH increases ulcer effects. Contact PCP if serious ADR. If dose missed-take ASAP (no-double). 2 weeks to work. AVOID ASPIRIN
Meloxicam Mobic NSAIDs Osteoarthritis & Rheumatoid Arthritis 7.5-15mg Dosage Cox inhibitor, decreasing prostaglandins EtOH increases ulcer effects. Contact PCP if serious ADR or signs of Hepatic failure. If dose missed-take ASAP (no-double). 2 weeks to work. AVOID ASPIRIN
Naproxen Naprosyn NSAIDs Mild-Moderate Pain Dymenorrhea. Rheumatoid Arthritis, Acute Gout 250-500mg Dosage Cox inhibitor, decreasing prostaglandins Tired, EtOH increases ulcer effects. Contact PCP if serious ADR. If dose missed-take ASAP (no-double). Take on empty stomach, 2 weeks to work
Varenicline Chantix Smoking Cessation Aid Smoking Cessation 0.1-1mg Dosage Partial Agonist at Nicotinic Receptors Caution while driving/mental tasks. Contact PCP for severe ADR. Take after food with water. Begin dose 1 week prior to smoking cessation taper
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