Human Brain midterm

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Chemistry Flashcards on Human Brain midterm, created by Henry Sokol on 16/03/2017.
Henry Sokol
Flashcards by Henry Sokol, updated more than 1 year ago
Henry Sokol
Created by Henry Sokol almost 9 years ago
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Resource summary

Question Answer
1 epidermis
2 neural plate
3 neural crest
4 mesoderm
The neural groove becomes the ________ plate of the neural tube. floor plate
The floor plate secretes __________. Shh (Sonic hedgehog)
The roof plate secretes _________. BMP
The neural crest gives rise to the _________. PNS
Sensory neurons in the dorsal root ganglia are part of the CNS (T/F). FALSE
Motor neurons in the ventral spinal cord are part of the CNS (T/F). TRUE
Vasoconstriction is monitored by which brain region? hypothalamus
Shivering is monitored by which brain region? hypothalamus
Burrowing under wood shavings is monitored by which brain region? cerebrum
Vasodilation is monitored by which brain region? hypothalamus
Water retention is monitored by which brain region? hypothalamus
Panting is monitored by which brain region? hypothalamus
Moving to a cooler part of the cage is monitored by which brain region? cerebrum
Where is ACTH made? anterior pituitary
Where is cortisol made? adrenal cortex
Where is corticotropin releasing hormone (CRH) made? hypothalamus
Orexigenic (hunger) or catabolic tone is monitored by which neuropeptide? alpha melanocyte-stimulating hormone
Which neuropeptide is released in childbirth? oxytocin
The PRIMARY AUDITORY CORTEX (A1) is in which lobe? temporal
The PRIMARY MOTOR CORTEX (M1) is in which lobe? frontal
The PRIMARY SOMATOSENSORY CORTEX (S1) is in which lobe? parietal
The PRIMARY VISUAL CORTEX (V1) is in which lobe? occipital
The HIGHER AREAS OF THE VENTRAL VISUAL STREAM (THE WHAT?) is in which lobe? temporal
The HIGHER AREAS OF DORSAL VISUAL STREAM (THE WHERE?) is in which lobe? parietal
Broca's area/speech production is in which lobe? frontal
Wernicke's area/speech comprehension is in which lobe? temporal
Gustatory area within lateral sulcus is in which lobe? insular
Border of the cerebral cortex is in which lobe? limbic
What structure connects the left and right hemispheres? corpus callosum
What structure separates the left and right hemispheres? sagittal fissure
What structure separates the allocortex and neocortex? cingulate sulcus
What structure separates the frontal and parietal lobes? central sulcus
What structure separates the temporal from the other lobes? lateral sulcus
Which type of cell is a type of myelinating neuroglia that is affected in multiple sclerosis? oligodendrocyte
Which type of cell is a type of myelinating neuroglia of the peripheral nervous system? Schwann cell
Which type of cell is a neuroepithelial cell forming the cerebral spinal fluid? ependymal cell
Which type of cell is a neuroepithelial cell that supports radial migrations? radial glia
Which type of cell are phagocytes of the central nervous system? microglia
Which type of cell is a star-shaped neuroglia that recycles transmitters of glutamate (L-glutamic acid and GABA)? astrocyte
Which molecule is the major EXCITATORY neurotransmitter in the brain? L-glutamic acid
Which molecule is the major INHIBITORY neurotransmitter in the brain? GABA
Which molecule is the neurotransmitter of pyramidal cells of cerebral cortex? L-glutamic acid
Which molecule is the neurotransmitter of Purkinje cells of the cerebral cortex? GABA
Which molecule is the enzyme that makes GABA? GAD
Which molecule is the enzyme that degrades GABA? GABA transaminase
Dendritic spines are presynaptic compartments (T/F). FALSE
Dendritic spines are found only on dendrites of glutaminergic neurons (T/F). FALSE
Dendrites integrate and propagate post-synaptic signals to the cell body (T/F). TRUE
The diameter of axons tapers going away from the neuron cell body (T/F). FALSE
Nodes of Ranvier on myelinated axons are sites of synaptic excitation (T/F). FALSE
Pyramidal cells that target the association to other areas of ipsilateral hemisphere? L2
Pyramidal cells that target commisure to like areas of contralateral hemisphere? L3
Pyramidal cells that target reciprocal modulator (READ) of thalamic input? L6
Pyramidal cells that targets the same as the "granular layer"? L4
Pyramidal cells that target the subcortical target and non-reciprocal driver (WRITE) of higher-order thalamic relays? L5
Where does FIRST-ORDER THALAMIC VISUAL RELAY occur? lateral geniculate nucleus (LGN)
Where does HIGHER-ORDER THALAMIC VISUAL RELAY occur? pulvinar
Where is the CORTICAL SITE OF COLOR BLINDNESS? V4
Where is the CORTICAL SITE OF FACE AGNOSIA? fusiform face area
Where is the CORTICAL SITE OF MOTION BLINDNESS? MT/V5
Where is the RETINAL SITE OF COLOR BLINDNESS? cone cell
Where is the RETINAL SITE OF NIGHT VISION? rod cell
9 roof
10 alar
11 basal
12 floor
15 forebrain
16 midbrain
17 hindbrain
18 spinal cord
19 lateral ventricles
20 third ventricle
21 cerebral aquadeuct
22 fourth ventricle
23 central canal
24 cerebral cortex
25 basal ganglia
26 thalamus
27 hypothalamus
28 tectum
29 tegmentum
30 pons
31 medulla
39 pineal gland
40 epithalamus
41 hypothalamus
42 posterior pituitary
43 optic chiasm
44 anterior pituitary
45 posterior pituitary
33 major axon
34 collateral axons
35 basal dendrites
36 apical dendrite
37 oblique branches
38 apical tuft
3 hippocampus
4 neocortex
5 striatal ridge
6 pallidal ridge
7 thalamic eminence
8 hypothalamus
Which nucleus is NOT part of the striatum? pallidum
Which projection neurons do NOT use GABA? thalamic
(Direct or Indirect paths) D1 dopamine receptors on striatal neurons direct
(Direct or Indirect paths) D2 dopamine receptors on striatal neurons indirect
(Direct or Indirect paths) Relays via the external segment of globus pallidus (GPe) indirect
(Direct or Indirect paths) Outputs via the internal segment of globus pallidus (GPi) both
15 cortex
16 striatum
17 pallidum
18 thalamus
Dominant mutation in Huntingtin gene. Huntington
Drug-induced choreoathetosis. dyskinesia
Drug stimulation of dopamine neurons in VTA or synapses in nucleus accumbens. drug addiction
Injury of subthalamic nucleus. hemiballismus
Loss of nigral dopamine neurons Parkinson
Loss of striatal neurons Huntington
Marche à petits pas, or festinating gait Parkinson
Micrographia, decreasing amplitude and slowing rate when handwriting Parkinson
Motor and vocal tics. Tourette
Recurrent intrusive thoughts and ritualistic behavior. OCD
Tremor while resting. Parkinson
Tremor during active movement. essential tremor
Chorea has graceful, dance-like movements (T/F) true
Chorea has stereotyped, repeated movements (T/F) false
Chorea has a premonitory urge and sense of relief on completion (T/F) false
Athetosis has writhing movement of the body or face. (T/F) true
Compulsions have a premonitory urge and sense of relief on completion (T/F) true
Tics are stereotyped, repeated movements and vocalizations. (T/F) true
Tics have a premonitory urge and sense of relief on completion. (T/F) true
38 L-tyrosine
39 L-dopa
40 dopamine
41 norepinephrine
42 epinephrine
43 tyrosine hydroxylase
44 DOPA decarboxylase
45 dopamine b-hydroxylase
Rate-limiting step in dopamine synthesis: tyrosine hydroxylase
L-DOPA acts on dopamine receptors in Parkinson disease (True/False) false
Knowing that reserpine depletes dopamine from synaptic vesicles, this drug should improve movement in Parkinson disease (True/False) false
Dopamine is inactivated by: (a) decarboxylation (b) hydrolysis (c) reuptake reuptake
Dopamine is optically active (True/False) false
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