B-1 Adrenergic Receptor ANTAGONIST.
Acts on receptors in heart ONLY, not
lungs (asthma). Decreases HR, CO & BP.
POstural Hhypotension an issue. DONT
prescribe NSAIDS - Do the same thing so
will double up. Dont us Mepivicaine as
both metabolised by liver
Cilazapril
ACE Inhibitor
Stops ACE from
converting
Angiotensin1 -->
Angiotensin2
(Vasoconstrictor) = Net
Vasodialtion. Dry
cough common,
Angiodema 0.1-0.07%
MI, Stroke
Asprin
Atherosclerosis
Simvastatin
HMG-CoA
Reductase Inhibitor
Decreases Total Serum
Cholesterol. Prevents
plaques progressing.
Angiodema. Interactions
w AB's & AF's
Pain
Paracetamol
Cox-2 Inhibitor
Not antithrombotic as cox-2 selective. Good for
mild dental pain. Max dose 10x 500mg
tabs/24hrs. May cause liver toxicity
Ibuprofen
Asprin
Inflammation
Ibuprofen
NSAID
Anti-inflammatory, Anlagesic,
Antipyretic. Inhibits Prostaglandin
synthesis = Decreases pain, heat,
swelling etc. Careful not to OD.
Asprin
Cox Inhibitor
Anti-inflam, Anti-pyretic,
Anti-platelet. Increases bleeding
after exo, endo etc
Asthma
Salbutamol
B-2 Adrenergic
Receptor AGONIST
For Treatment of
Bronchospasms in Asthma.
"Reliever" Dry mouth, Oral
Candidosis. Careful with NSAID
interaction. B-1 agonsit NSAIDS
harmful in asthma attacks
GORD/ Gastric
Ulcers
Omeprazol
Proton Pump Inhibitor
Decreases Acid Production
in Stomach. Px may have ^^
Erosion in mouth - Occlusal
Max Molars. May interfere w
antifunglas
Contraception
OCP
Oestrogen + Progesterone
Some Antibiotics/ Antifungals may affect
OCP function. Usually decreases its
absorption & increases its secretion via
plasma binding protein.
Osteoperosis
Alendronate
Bisphosphonate
Decreases Bone turnover
How? osteoblast >
osteoclast activity Can cause
bisphosphonate ONJ
Painless necrosis usually
after exo or apical infection