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Internal Organization of the cell

Membrane Structure
1. Plasma membrane
  1. Encloses cell, defines its boundaries and maintains the essencial differences between cytosol and extracellular environment
  2. Eucaryotic cells, membranes, endoplasmic reticulum, golgi apparatus, mitochondria, membrane-enclosed
    1. 4 phospholipids
      1. phosphatidylcholine
      2. phosphatidylethanolamine
      3. phosphatidylserine
        Translocation in apoptotic cell by two mechanism
        The phospholipid translocator is inactivated
        Scramblase that transfer phospholipids in both directions is activared
      4. sphingomyelin
2. Ion gradients
  1. Across membrane, activities of membrane proteins, synthesize ATP, movement of selected solute,produce electrical signals
3. thin film of lipid and protein molecules held by noncovalent interactions
4. Lipid Bilayer
  1. Fluid structure, impermeable barrier to water-solube molecules
    1. Lipid Molecules
      1. Amphipathics that have hydrophilic end and a hydrophobic end
      2. Phospholipids
        Have a polar head group and two hydrophobic hydrocarbon tails
        phospholipases
        activated by extracellular signals to cleave phospholipid
    2. depends on composition and temperature
      1. Cholesterol
        enhance the permeability-barrier
      2. glycolipids
  2. Liposomes
    1. spherical vesicles
  3. Black Membrane
    1. Planar billayers
  4. Phospholipid translocators
    1. Membrane-bound enzymes, catalyze the rapid flip-flop of phospholipids
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Internal Organization of the cell

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	Created by Cesar Corona Flores almost 9 years ago

	Copied by LCM almost 9 years ago