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Cáncer Colon

Description

Mind Map on Cáncer Colon, created by adahemy.tm on 04/05/2014.

Mind Map by adahemy.tm, updated more than 1 year ago

	Created by adahemy.tm over 10 years ago

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Resource summary

Cáncer Colon

Epidemiología
1. 3er lugar incidencia
2. Incidencia 46/100,000
  1. Media edad 69
Factores Riesgo
1. Demográfico
  1. Edad
2. Biológicos
  1. Anatómico
    1. >lado derecho
3. Ambientales
  1. Dieta carne roja
    1. Sedentarismo
      1. Alcoholismo
Patogenia
1. Vía clásica
  1. Mutación APC
    1. B catenina se acumula
    2. Activa KRAS
      1. p53 mutado
2. Inestabilidad
  1. Microsatelites
    1. Crecimiento no controlado
    2. Perdida BAX
      1. Supervivencia
        Clones anormales
Morfología
1. Colon proximal
  1. Masas polipoides
2. Colon distal
  1. Lesiones anulares
Clínica
1. Dolor
  1. Masa
2. Sangrado
  1. Diarrea
    1. Pérdida ponderal
  2. Obstrucción
Diagnóstico
1. Colonoscopia
2. Toma de biopsia
Tratamiento
1. Colectomía radical

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