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Yasser is falling behind

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Mind Map on Yasser is falling behind, created by shahid alzaghari on 10/11/2017.
shahid alzaghari
Mind Map by shahid alzaghari, updated more than 1 year ago
shahid alzaghari
Created by shahid alzaghari over 6 years ago
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Yasser is falling behind
  1. Yasser 2 years 1 month old
    1. Main diagnosis
      1. Growth Hormone Deficiency
        1. Growth hormone
          1. Produced (somatotrophs) and secreted in
            1. exerts effects on almost all tissues
              1. Adipose tissue
                1. Cartilage
                  1. Bone
                    1. Liver
                      1. Muscles
                        1. Indirectly
                          1. Directly
                            2. 191 amino acids-polypeptide chain-2 internal disulfide bridges
                              2. The pituitary gland does not make enough growth hormone
                                1. Criteria to Initiate Evaluation for GHD
                                2. Clinical presentation:
                                  1. Congenital
                                    1. Exaggerated jaundice in the first days
                                      1. Growth failure
                                        1. Slower developmental milestones
                                          1. Reduced energy
                                            1. Impaired concentration
                                              1. Memory loss
                                      2. Acquired
                                        1. Delayed puberty
                                          1. Baldness in men
                                            1. Reduced bone mass and osteoperosis
                                              1. Reduced energy
                                                1. Increased body fats (around waist line)
                                      3. Epidemiology
                                        1. 3-10 in every 100 babies are born smaller than normal
                                        2. Investications:
                                          1. Growth chart
                                            1. Normal
                                              2. GHD
                                              3. Physical examination
                                                2. Tests:
                                                  1. Blood tests
                                                    1. GH
                                                      1. IGF-1
                                                        1. CBC
                                                          1. Serum protein
                                                          2. Karyotyping
                                                            1. X-ray
                                                              1. Left wrist
                                                          3. Treatment
                                                      2. Anatomy and histology of pituitary gland
                                                        1. Brain
                                                          1. Forebrain
                                                            1. Diencephalon
                                                              1. Ventral: hypothalamus
                                                                1. Pituitary gland
                                                                  1. Hypothalamic nuclei and neuroendocrine cells
                                                                    1. Adenohypophysis
                                                                      1. Pars distalis
                                                                        1. Pars intermedia
                                                                          1. Pars tuberalis
                                                                          2. Neurohypophysis
                                                                            1. Pars nervosa
                                                                              1. Infundibular stem
                                                                                1. Median eminence
                                                                          2. NORMAL growth rate
                                                                            1. Height
                                                                              1. Weight
                                                                                1. yasser was taken to the M&CH center (maternity hospital) where they get so many services and check the child health and normal growing
                                                                                  1. Services:
                                                                                    1. All pediatric services
                                                                                      1. Emergency services
                                                                                        1. and others....
                                                                                      2. Follow the patient up
                                                                                        1. To increase compliance
                                                                                          1. To adjust the doses

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