12194204
Description
Mind Map by fatima alkhateeb, updated more than 1 year ago
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Created by fatima alkhateeb
over 6 years ago
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Celiac disease
- Anatomy
- Duodenum
- Jejunum
- Ileum
- Duodenum
- Definition
- Immune mediated damage of small
bowel villi due to gluten exposure
- Immune mediated damage of small
bowel villi due to gluten exposure
- Causes
- Inappropriate T cell and IgA
mediated response against gluten
in genetically predisposed persons
- Gliadin is deaminated which is
then grabbed by APC’s and are
presented via MHC II to Th cells
which mediate tissue damage
- Gliadin is deaminated which is
then grabbed by APC’s and are
presented via MHC II to Th cells
which mediate tissue damage
- Inappropriate T cell and IgA
mediated response against gluten
in genetically predisposed persons
- Signs and
symptoms
- Steatorrhea
- Weight loss
- Failure to
thrive
- Vitamin
deficiency
- Failure to
thrive
- Pallor (anemia)
- Weight loss
- Steatorrhea
- Investigations
- Endoscopy
- Genetic testing
- Histology
- Endoscopy
- Pathology
- Management
- Gluten-free diet
- Gluten-free diet
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