SANA WITH RASH AND EASY BRUISING

Bleeding causes
1. Other
  1. Brain trauma
2. Disorders
  1. Platelets
    1. Leukemia
    2. Thrombocytopenia.
  2. Coagulation factors
    1. Hemophilia
    2. Vitamin K deficiency
    3. Liver disease
Clinical Appearance
1. Petechiae
  1. red, brown or purple
  2. Flat
  3. Resemble rash
2. Purpura
  1. do not blanch on pressure
  2. palpable
  3. 0.3–1 cm
3. Ecchymosis
  1. subcutaneous spot
  2. larger than 1 cm
  3. bruise
Lab test
1. CBC
2. Blood Smear
3. Bone Marrow Tests
Thrombocytopenia
1. Risk factors
  1. Bone marrow cancer
  2. poisonous chemicals
  3. Viral infections
  4. chemo therapy
  5. drugs
  6. Spleenomegaly
2. Complications
  1. Excessive bleeding after minor injury
  2. brain stroke
  3. complications of lupus
  4. severe anemia
Pharmacology
1. Antiplatelet drugs
  1. Aspirin
  2. ADP inhibitors
    1. ticlopidine
    2. clopidogrel
    3. prasugrel
  3. Phosphodiesterase
2. THROMBOLYTIC AGENTS
  1. t-PA derivatives
  2. Streptokinase
3. Anticlotting drugs
4. Anticoagulants
  1. Heparin
  2. Direct factor Xa inhibitor
  3. Warfarin
  4. Direct thrombin inhibitor
bone marrow examination
1. biopsy
  1. a needle to draw solid
2. aspiration
  1. a needle to draw fluid

Resource summary

	Created by Dua Ga over 6 years ago