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Slippery Path (Abused drugs)

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Mind Map on Slippery Path (Abused drugs), created by Abdelrahman Nouh on 08/10/2018.
Abdelrahman Nouh
Mind Map by Abdelrahman Nouh, updated more than 1 year ago
Abdelrahman Nouh
Created by Abdelrahman Nouh about 6 years ago
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Resource summary

Slippery Path (Abused drugs)
  1. classified into
    1. legal
      1. alcohol
        1. cigarettes
          1. caffeine
            1. inhalants
            2. over the counter
              1. codeine
                1. vitamins
                2. illegal
                  1. prohibited by UAE rules & laws
                    1. in 1995
                      1. death penalty for drug abusers
                      2. in 2016
                        1. rehabilitation rather than penalties
                          1. in centers
                            1. Ownak social
                              1. Erada
                                1. NRC
                                  1. sections
                                    1. psychiatric
                                      1. medical
                                        1. social work
                                          1. psychology
                                        2. provide services
                                          1. treatment
                                            1. education
                                      2. examples
                                        1. magic mushroom
                                          1. heroin
                                            1. cocaine and crack
                                              1. marijuana
                                            2. prescribed
                                              1. barbiturates
                                                1. stimulants
                                                  1. pain killers
                                                    1. anabolic steroids
                                                  2. mechanism of action
                                                    1. binding of the drug to the receptor
                                                      1. forming DR complex
                                                        1. produces effect
                                                        2. receptors can respond to
                                                          1. agonists
                                                            1. give the same effect of the natural drug
                                                              1. types
                                                                1. partial
                                                                  1. inverse
                                                                2. antagonists
                                                                  1. inhibits the binding of
                                                            2. demography
                                                              1. name: Ali
                                                                1. age: 26
                                                                  1. reason of death
                                                                    1. drug overdose
                                                                      1. accidentally
                                                                        1. intentionally
                                                                          1. intolerable dose of
                                                                        2. addiction type
                                                                          1. poly-drug use
                                                                            1. 2 or more drugs used at the same time or over a short period of time
                                                                              1. effects
                                                                                1. depend on
                                                                                  1. types of drugs combined
                                                                                    1. more dangerous if 2 or more drugs with the same physical effects are taken together
                                                                                      1. ex: 2 stimulants: cocaine & ecstasy
                                                                                      2. toxicity
                                                                                      3. setting
                                                                                        1. time
                                                                                          1. place
                                                                                          2. person
                                                                                            1. ex: mood
                                                                                  2. leads to
                                                                                    1. addiction
                                                                                      1. dependency
                                                                                        1. risk factors
                                                                                          1. addicted parents
                                                                                            1. peer pressure
                                                                                              1. easy access to drugs in the community
                                                                                                1. involving at young age
                                                                                                  1. puberty
                                                                                                    1. activation of hypothalamo-pituitary gonadal axis
                                                                                                      1. pulsatile GnRh
                                                                                                        1. age
                                                                                                          1. boys: 9-18
                                                                                                            1. secondary characteristics
                                                                                                              1. facial hair
                                                                                                                1. loud, deep voice
                                                                                                                  1. developed muscles
                                                                                                                    1. broad shoulders
                                                                                                                  2. girls: 8-16
                                                                                                                    1. secondary characteristics
                                                                                                                      1. high pitched voice
                                                                                                                        1. development of breasts
                                                                                                                          1. broad pelvis & narrow shoulders
                                                                                                                            1. pubic & axillary hair
                                                                                                                        2. psychological issues
                                                                                                                          1. males
                                                                                                                            1. more aggressive
                                                                                                                              1. more production
                                                                                                                              2. females
                                                                                                                                1. more emotional
                                                                                                                              3. abnormalities
                                                                                                                                1. delay
                                                                                                                                  1. boys: after 20
                                                                                                                                    1. girls: after 17
                                                                                                                                    2. precocious
                                                                                                                                      1. below the age of 8
                                                                                                                                        1. pseudo
                                                                                                                                          1. only secondary characteristics
                                                                                                                                          2. true
                                                                                                                                            1. secondary characteristics & gametogenesis
                                                                                                                                2. preventive factors
                                                                                                                                  1. employment
                                                                                                                                    1. good income
                                                                                                                                      1. parental education
                                                                                                                                      2. if drug use stopped abruptly
                                                                                                                                        1. withdrawal symptoms
                                                                                                                                          1. sweating
                                                                                                                                            1. depression
                                                                                                                                              1. decreased dopamine
                                                                                                                                                1. due to
                                                                                                                                              2. tremors
                                                                                                                                                1. nausea
                                                                                                                                                  1. insomnia
                                                                                                                                            2. examination & investigation
                                                                                                                                              1. abdomen
                                                                                                                                                1. hepatomegaly
                                                                                                                                                  1. overwhelmed from
                                                                                                                                                    1. detoxification
                                                                                                                                                      1. phase 1
                                                                                                                                                        1. Functionalization/Biotransformation
                                                                                                                                                          1. reduction
                                                                                                                                                            1. hydrolysis
                                                                                                                                                              1. oxidation/hydroxylation
                                                                                                                                                                1. adding OH
                                                                                                                                                                  1. by
                                                                                                                                                            2. phase 2
                                                                                                                                                              1. conjugation
                                                                                                                                                                1. adding conjugates to make the substance more polar and easily excreted
                                                                                                                                                                  1. 4G
                                                                                                                                                                    1. glaucouronic acid
                                                                                                                                                                      1. glycine
                                                                                                                                                                        1. glutamine
                                                                                                                                                                          1. glutathoion
                                                                                                                                                                          2. M
                                                                                                                                                                            1. methyl
                                                                                                                                                                            2. S
                                                                                                                                                                              1. sulfate
                                                                                                                                                                              2. A
                                                                                                                                                                                1. acetate
                                                                                                                                                                                2. T
                                                                                                                                                                                  1. thiosulfate
                                                                                                                                                                    2. cardiovascular
                                                                                                                                                                      1. tachycardia
                                                                                                                                                                        1. murmurs
                                                                                                                                                                        2. neurological
                                                                                                                                                                          1. cognitive impairment
                                                                                                                                                                            1. tremor
                                                                                                                                                                            2. blood test
                                                                                                                                                                              1. liver enzymes
                                                                                                                                                                                1. cytochrome P450
                                                                                                                                                                                2. CBC
                                                                                                                                                                                  1. urine & serum toxicology
                                                                                                                                                                                    1. HIV
                                                                                                                                                                                      1. amylase & lipase
                                                                                                                                                                                        1. blood alcohol
                                                                                                                                                                                        2. appearance
                                                                                                                                                                                          1. nasal irritation
                                                                                                                                                                                            1. skin
                                                                                                                                                                                              1. needle marks
                                                                                                                                                                                              2. conjuctival irritation
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