Losing weight

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Mind Map on Losing weight, created by Dana Ali on 25/11/2018.
Dana Ali
Mind Map by Dana Ali, updated more than 1 year ago
Dana Ali
Created by Dana Ali about 6 years ago
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Resource summary

Losing weight
  1. Anatomy of the thyroid
          1. Thyroid hormone
              1. TSH
                1. upregulates activity of iodide pump
                  1. Endocytosis of iodinated thyroglobulin
                    1. Upregulates TPO and thyroglobulin
                    2. thyroid follicles cells
                      1. Thyroxine (T4)
                        1. Tri-iodothyronine (T3)
                          1. Reverse,rT3
                          2. parafollicular cells
                            1. Calcitonin
                        2. Hyperthroidism
                          1. Causes
                            1. 2-Functioning adenoma and toxic multinodular goiter
                              1. Excessive intake of thyroid hormones
                                1. Abnormal secretion of TSH
                                  1. Graves Disease
                                    1. B-cell production of IgG antibodies
                                      1. Mutations in HLA-DR3 & HLA-B8
                                        1. Exophthalmos
                                          1. Pretibial Myxedema
                                            1. Thyroid Acropathy
                                        2. Signs and Symptoms
                                          1. Nervousness and irritability
                                            1. Increased resting heart rate
                                              1. Heat intolerance
                                                1. Tremors
                                                  1. Weight loss
                                                    1. Frequent bowel movements
                                                    2. Management
                                                      1. antithyroid drugs
                                                        1. radioactive iodine
                                                          1. surgical removal
                                                            1. Adjunctive therapy
                                                              1. Beta blockers
                                                                1. Iodine
                                                                  1. Steroids
                                                                  2. Adverse effects
                                                                    1. agranulocytosis
                                                                      1. congenital goiter
                                                                        1. Skin rash
                                                                          1. neutropenia
                                                                      2. Goiter
                                                                        1. Hoarseness
                                                                          1. Difficulty swallowing
                                                                            1. Difficulty breathing
                                                                              1. Risk Factors
                                                                                1. A lack of dietary iodine
                                                                                  1. female
                                                                                    1. autoimmune disease
                                                                                      1. Radiation exposure
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