She had itchy erythematous papules & plaques,
pus & yellowish crust, ulceration, irregular
cord-like palpable thickenings, and palpable
axillary lymph nodes
Differential Diagnosis
Leishmaniasis
Epidemiology
According to the Global Burden of Disease Study
from 2015, the leishmaniases are the third most
important vector-borne disease after malaria and
dengue, with an estimated 1.4 million all-age
disability-adjusted life years (a 3.8% increase
between 2005 and 2015). The leishmaniases are
endemic in more than 90 countries in the tropics,
neotropics, and southern Europe. An estimated 0.7 to
1 million cases are diagnosed each year, with 20,000
to 30,000 deaths. According to the World Health
Organization, over 1 billion people living in endemic
areas are at risk of infection.
Etiology & Life Cycle
Leishmaniasis is a localized or systemic
infectious disease, caused by the obligate
intramacrophage protozoa of the genus
Leishmania and transmitted to humans by the
bite of infected female phlebotomine sand flies.
Types
Cutaneous Types: Localized
cutaneous leishmaniasis,
Diffuse cutaneous
leishmaniasis, and Mucosal
leishmaniasis (sometimes
classified as a separate subtype
on its own)
Visceral Types: Visceral
leishmaniasis (also known
as kala-azar), and
Post-kala-azar dermal
leishmaniasis (PKDL)