null
US
Sign In
Sign Up for Free
Sign Up
We have detected that Javascript is not enabled in your browser. The dynamic nature of our site means that Javascript must be enabled to function properly. Please read our
terms and conditions
for more information.
Next up
Copy and Edit
You need to log in to complete this action!
Register for Free
29069493
A 36 yr old woman with Breast lump
Description
Mind Map on A 36 yr old woman with Breast lump, created by rania jumah on 25/02/2021.
Mind Map by
rania jumah
, updated more than 1 year ago
More
Less
Created by
rania jumah
over 3 years ago
16
0
0
Resource summary
A 36 yr old woman with Breast lump
Anatomy of breast
epithelial part
milk production
connective tissue part
cooopers ligament
blood supply
internal mammary artery
acromiothoracic artery & intercostal arteries
lateral thoracic artery
lymphatic drainge
lateral axillary node
pectoral nodes
subscapular nodes
central axillary nodes
infraclavicular nodes
parasternal nodes
supraclavicular nodes
apical axillary
ant./post. axillary
physiology of breast
estrogen
development of stromal tissue of breast
involved in ductal development
deposition of fat in breast
progesterone
responsible for lobular development & differentiation of epithelium
enlargement of alveolar cells which become secretory in nature
prolactin
most imp hormone for lactogenesis in late pregnancy and postpartum period
lactation
mammogenesis
process of growth & development of mammary gland
lactogenesis
initiation of milk secretion
galactopoiesis
maintenance of milk secretion
milk -let down reflex
oxytocin
contraction of myoepithelial cells
went for a routine health check
mammogram performed
lesions identified
history was taken
family history of breast cancer
risk factor for breast cancer
advancing age
female gender
ethnicity
white women
hormone replacement therapy
first child after age 30
overweight and obese women
alcohol/smoking
early period and late menopause
physical exam done
breast examination
no nipple discharge
no axillary lymphadenopathy
no palpable breast mass
wide local excision of breast lump performed
revealed infiltrating ductal breast carcinoma
Breast carcinoma
management
systemic
chemotherapy
cyclophosphamide
doxorubicin
methotrextate
hormonal therapy
ER positive
PR positive
targeted therapy
HER-2 targeted therapies
local
surgery
lumpectomy
advatage: preserve appearance and less invasive
disadvenatge: radical therpay may be needed after and chances of local reoccurance
contrainfications"
previous radiation/multiple masses/large tumors
mastectomy
subtypes
modified radical mastectomy/radical mastectomy/simple mastectomy/skin sparingmastectomy
indications
previous radiation/multiple masses/large tumor/ diffsue malignant carcionma
breast reconstruction
tissue expansion
flap reconstruction
indications
previous radiotheraphy, radical mastectomy, tight mastectomy scar
implant reconstruction
Follow up
measure level of blood tumor markers
pelvic exam
doctor visits
imaging tests
mammograma
prognosis
average 5 year survival rate ior people with breast cancer is 90%
average 10 year survival for breast cancer is 85%
if spread to regional lymph nodes 5 year survival is 83%
if cancer spreads to distant parts of body 5 year survival rate is 27%
classification
ductal
ductal carcinoma in situ
malignant proliferation of cells in duct
no invasion to basement membrane
it doesnt produce mass, detected as calcification
paget disease
DIC that extends up tp duct and invade skin of nipple
nipple ulceration and erythema
invasive ductal carcinoma
present as mass
has 4 subtypes
tubular
good progosis
tumor lacks myoepithelial cells
medullary
hih grade cells. lymphomas and plasma cells
good prognosis
mucinous
tubules in mucus pools
good prognosis
inflammatory
poor prognosis, in old woman, in dermal lympahtics, inflammed swollen breasts
tubular
lobular carcinoma in situ
multifocal & bilateral
no invasion, masses or calcifications
discovered by accident
malignant proliferation of cell in lobule
invasive lobular carcinoma
single file pattern
signet cell morphology
no duct formation
lacks f-cadherin
investigations
blood tests
tumor markers
tissue tumor markers
estrogen and progesterone receptors
human epidernal growth factor
serum tumor markers
CEA
CA 27.29
CA 15-3
biopsy
fine needle aspiration
core needle biopsy
surgical biopsy
mammogram
MRI
gather more information about area of suspicion
screen high risk women
moniter treatment
ultrasound
usuualy after mamogram
detect abnormality type
before mammogram to evaluate lump
molecular classification
Luminal A
ER+
luminal B
ER+ HER2+
her2 +ve
HER2-
basal like
PR-. ER- HER2-
screening guidelines
75+
every other year while life expectancy is 10+
50-74
every other year starting at 55
40s
45+ every year
disadventages
false negative results
overdiagnosis and overtreatment
false positive results
types of mammograms
screening mammography
diagnostic mammography
Show full summary
Hide full summary
Want to create your own
Mind Maps
for
free
with GoConqr?
Learn more
.
Similar
Unit 3.1: Marketing
nk_
A-Level Economics: Supply and Demand
cian.buckley+1
Great Expectations
Jodee Phillips
AS biology Exchange and transport flashcards
jenna.ridley
An Gnáthrud
xlauramartinx
English Placement Test
CoachDanielDixon
“The knower’s perspective is essential in the pursuit of knowledge.” To what extent do you agree with this statement?
Lucia Rocha Mejia
Science Unit 1 flashcards
bamoscato
Expertise in Project Management
tonesha_g
Types of Learning Environment
Brandon Tuyuc
Účto Fífa 3/6
Bára Drahošová
Browse Library