Copy and Edit

Alzheimer's disease

Description

Mind Map on Alzheimer's disease, created by H S on 18/10/2021.
H S
Mind Map by H S, updated more than 1 year ago
H S
Created by H S about 3 years ago
10
0
0

Resource summary

Alzheimer's disease
  1. Causes
    1. Genetic
      1. APP
        1. Chr 21
          1. Neuronal repair
          2. PSN-1/2
            1. Chr 1/14
              1. y-secretase
              2. APOE
                1. Lipid metabolism
                  1. Chr 12/19
                  2. Tau
                    1. Chr 17
                      1. Microtubule associated
                  3. Signs and symptoms
                    1. Memory loss
                      1. Limbic system
                        1. Cortical structures
                          1. Limbic lobe
                            1. Subcallosal area
                              1. Cingulate gyrus
                                1. Isthmus of limbic lobe
                                  1. Parahippocampal gyrus
                                    1. Uncus
                                    2. Hippocampal formation
                                      1. Hippocampus proper
                                        1. Subiculum
                                          1. Dentate gyrus
                                            1. Entorhinal cortex
                                            2. Septa area
                                              1. Orbito-frontal cortex
                                              2. Subcortical structures
                                                1. Anterior nucleus of thalamus
                                                  1. Hypothalamus
                                                    1. Mammillary bodies
                                                    2. Amygdala
                                                    3. Connecting pathways
                                                      1. Fornix
                                                        1. Mammilothalamic tract
                                                          1. Stria temrinalis
                                                            1. Cingulum
                                                              1. Longitudinal stria
                                                                1. Medial forebrain bundle (MFB)
                                                                  1. Anterior commisure
                                                                2. Types of memory
                                                                  1. Short term memory
                                                                    1. Intermediate memory
                                                                      1. Long term memory
                                                                        1. Sensory memory
                                                                        2. Physiology of memory
                                                                          1. Habituation
                                                                            1. Inhibition of pathways
                                                                              1. Inhibiton of presynaptic Ca2+ influx
                                                                                1. Less release of neurotransmitters
                                                                                2. Sensitization
                                                                                  1. Facilitation of pathways
                                                                                    1. Stimulation of presynaptic Ca2+ influx
                                                                                      1. Increased release of neurotransmitters
                                                                                3. Dementia
                                                                                  1. Vascular dementia
                                                                                    1. Lewy body dementia
                                                                                      1. Frontotemporal dementia
                                                                                        1. Mixed dementia
                                                                                          1. Al cohol related dementia
                                                                                          2. Pathophysiology
                                                                                            1. Formation of plaques
                                                                                              1. Formation of neurofibrillary tangles
                                                                                                1. Plaques and tangles
                                                                                                  1. Inflammation (neuronal injury)
                                                                                                    1. Neuronal death
                                                                                                      1. Disrupt neuronal signalling
                                                                                                    2. Investigations
                                                                                                      1. Mini-mental state examination (MMSE)
                                                                                                        1. Assess
                                                                                                          1. Orientation
                                                                                                            1. Registeration
                                                                                                              1. Attention and calculation
                                                                                                                1. Recall
                                                                                                                  1. Language
                                                                                                                    1. Copying
                                                                                                                  2. Blood tests
                                                                                                                    1. CBC
                                                                                                                      1. ESR
                                                                                                                        1. Liver/kidney function tests
                                                                                                                          1. Blood glucose
                                                                                                                            1. Thyroid function tests
                                                                                                                              1. Blood culture
                                                                                                                                1. HIV test
                                                                                                                                2. Imaging
                                                                                                                                  1. PET
                                                                                                                                    1. CT/MRI
                                                                                                                                    2. Genetic testing
                                                                                                                                    3. Management
                                                                                                                                      1. Drugs
                                                                                                                                        1. Selective cholinesterase inhibitors
                                                                                                                                          1. Rivastigmine, Galantamine, Donepezil
                                                                                                                                            1. Side effects
                                                                                                                                              1. DUMBELSS
                                                                                                                                                1. Diarrhea
                                                                                                                                                  1. Urination
                                                                                                                                                    1. Myosis
                                                                                                                                                      1. Bronchospasm
                                                                                                                                                        1. Emesis
                                                                                                                                                          1. Lacrimation
                                                                                                                                                            1. Salivation/sweating
                                                                                                                                                        2. NMDA antagonist
                                                                                                                                                          1. Memantine
                                                                                                                                                            1. Side effects
                                                                                                                                                              1. Dizziness
                                                                                                                                                                1. Confusion
                                                                                                                                                                  1. Hallucinations
                                                                                                                                                            2. Risk factors
                                                                                                                                                              1. Non-Modifiable
                                                                                                                                                                1. Age
                                                                                                                                                                  1. Family history
                                                                                                                                                                    1. Down syndrome
                                                                                                                                                                      1. Head injuries
                                                                                                                                                                      2. Modifiable
                                                                                                                                                                        1. Cardiovascular disease
                                                                                                                                                                          1. Smoking/Alcohol
                                                                                                                                                                            1. Obesity
                                                                                                                                                                              1. Diabetes
                                                                                                                                                                                1. Hypertension
                                                                                                                                                                                  1. Lack of sleep
                                                                                                                                                                                    1. Sedentary lifestyle
                                                                                                                                                                                      1. Lack of education
                                                                                                                                                                                        1. Seizure
                                                                                                                                                                                          1. Strokes

                                                                                                                                                                                        Media attachments

                                                                                                                                                                                        Show full summary Hide full summary

                                                                                                                                                                                        Want to create your own Mind Maps for free with GoConqr? Learn more.

                                                                                                                                                                                        Similar

                                                                                                                                                                                        Alzheimer's disease
                                                                                                                                                                                        Vaibhav Khanna
                                                                                                                                                                                        alzheimer's disease
                                                                                                                                                                                        um10ks
                                                                                                                                                                                        Weimar Germany 1919: The Spartacists and the constitution
                                                                                                                                                                                        Chris Clayton
                                                                                                                                                                                        French Vocab - Higher French
                                                                                                                                                                                        Moira Shepherd
                                                                                                                                                                                        An Inspector Calls - Themes
                                                                                                                                                                                        mhancoc3
                                                                                                                                                                                        Girls' and Boys' Education - A Mind Map
                                                                                                                                                                                        nikkifulps
                                                                                                                                                                                        CHEMISTRY C1 7
                                                                                                                                                                                        x_clairey_x
                                                                                                                                                                                        Edexcel Biology chapter 1
                                                                                                                                                                                        Anna Bowring
                                                                                                                                                                                        GCSE Chemistry C4 (OCR)
                                                                                                                                                                                        Usman Rauf
                                                                                                                                                                                        GCSE REVISION TIMETABLE
                                                                                                                                                                                        nimraa422
                                                                                                                                                                                        CUBAN MISSILE CRISIS
                                                                                                                                                                                        Olivia Andrews
                                                                                                                                                                                        Browse Library