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Immunodeficiency

Description

Mind Map on Immunodeficiency, created by Marwa Alqassim on 14/11/2021.
Marwa Alqassim
Mind Map by Marwa Alqassim, updated more than 1 year ago
Marwa Alqassim
Created by Marwa Alqassim over 3 years ago
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Resource summary

Immunodeficiency
  1. lead to
    1. Recurrent Infections
      1. Antifungal Drugs
        1. caused by
          1. lack of sleep
            1. Hereditary factors
              1. smoking
          2. could be
            1. primary (congenital)
              1. 10% of cases
                1. Digeorge syndrome
                  1. SCID
                    1. Types
                      1. ADA
                        1. autosomal recessive
                          1. accumulation of Adenosine, deoxyadenosine, dATP
                          2. normal catabolisim
                          3. IL2RG
                            1. X-linked
                            2. RAG1/2
                            3. Signs and Symptoms
                              1. Increased infections
                                1. failure to thrive
                                  1. weight loss
                                  2. Treatment
                                    1. Bone Marrow Transplantation
                                      1. Organ Donation
                                        1. In UAE 12 deceased donors saved more than 40 lives
                                        2. Re-vaccination for Recipients
                                          1. Checking for Compatibility
                                            1. Blood typing
                                              1. HLA typing
                                              2. inserting new hematopoietic stem cells
                                                1. from
                                                  1. Posterior & anterior iliac crest
                                                    1. Tibia
                                                      1. Sternum
                                                2. Investigations & Tests
                                                  1. Candida Skin Test
                                                    1. positive: normal immune system reaction
                                                    2. X-ray
                                                      1. ADA level
                                                3. secondary (acquired)
                                                  1. 90% of cases
                                                    1. AIDS
                                                      1. Hodgkin's lymphoma
                                                  2. How it differs from hypersensitivity?
                                                    1. hypersensitivity types
                                                    2. Depression
                                                      1. mood disorder that causes a persistent feeling of sadness and loss of interest in things once enjoyed
                                                        1. S&S
                                                          1. Loss of interest
                                                            1. Trouble sleeping
                                                              1. Slowed movements
                                                                1. Increased fatigue
                                                          2. Types
                                                            1. Major Depression
                                                              1. Persistent Depressive Disorder
                                                                1. Postpartum Depression
                                                                  1. Premenstrual Dysphoric Disorder
                                                            2. Diagnosis
                                                              1. DSM-V
                                                                1. WHODAS
                                                                2. Trreatment
                                                                  1. Antidepressants
                                                                    1. SSRI
                                                                      1. 5HT, NERI
                                                                        1. 5HT2A Antagonist
                                                                          1. MAOI
                                                                    2. ECT
                                                                      1. Psychological Therapy
                                                                      2. Causes
                                                                        1. Genetics
                                                                          1. Stress , Trauma
                                                                            1. medications
                                                                              1. imbalance in neurotransmitters
                                                                      3. Somatization
                                                                        1. one or more unexplained somatic symptoms for more than 6 months

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