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4308068
4.1 - Non Specific Defences
Description
Higher Human Biology Mind Map on 4.1 - Non Specific Defences, created by Calum Mooney on 14/01/2016.
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human biology
higher
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Calum Mooney
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Created by
Calum Mooney
almost 9 years ago
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Resource summary
4.1 - Non Specific Defences
Physical and Chemical Defences
Epithelial Cells
Form a physical barrier to prevent entry of pathogens
Skin
Produce secretions against infection
Mucus in trachea
Lysozyme in tears
Acid in the stomach
The immune system protects the body against pathogens, some toxins and cancer cells
Inflammatory Response
Caused by release of histamine by mast cells
Causes vasodilation of arterioles
Increases blood flow
Increased capillary permeability
Increased blood flow and secretion of cytokines
An accumulation of phagocytes
Delivery of antimicrobial proteins
Kill bacteria
Delivery of clotting elements
Form a clot to prevent microbes entering the bloodstream
Phagocytes and Natural Killer Cells
Phagocytes
Phagocytes and NK cells secrete cytokines
Stimulate the specific immune response
Phagocytes recognise surface antigen molecules on pathogens
Destroy the pathogen by phagocytosis
Natural Killer Cells
NK cells cause virally infected cells to destroy themselves by apoptosis
Cause the production of self-destructive/digestive enzymes within the virally infected cell
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