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NTDs

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Mind Map on NTDs, created by sam.hilton on 18/04/2013.
sam.hilton
Mind Map by sam.hilton, updated more than 1 year ago
sam.hilton
Created by sam.hilton over 11 years ago
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Resource summary

NTDs
  1. Formation of CNS
    1. Formation
      1. Shaping
        1. PCP pathway
          1. Cell fate
            1. Cytoskeletal changes
          2. Bending and fusion
            1. Hingepoints
          3. Types of NTD
            1. Spina bifida
              1. pathogenesis
                1. Hydroencephaly
                2. Enter text here
                3. Predisposing factors
                  1. Anti-epilepsy
                    1. Hyperthemia
                      1. Hypervitaminosia
                        1. Diabetes
                          1. Inositol
                          2. Fumanosin
                            1. Folic acid related
                              1. MTHFR
                                1. Autoantibodies against FR
                              2. Mouse models
                                1. Folate sensitive
                                  1. Cited2
                                    1. Splotch 2h
                                    2. Folate resistant
                                      1. ct/ct
                                        1. Eyelash
                                          1. grhl3 cDNA
                                            1. change cell prolif rates
                                              1. reduce NT
                                                1. cell division inhibitors
                                                2. Increase NC
                                                  1. Retinoic acid
                                                3. Inositol
                                                  1. Effects
                                                    1. in vivo
                                                      1. in vitro
                                                4. Diabetic
                                                  1. SELH/Bc
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